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Nephrogenic Calciphylaxis Arising After Bariatric Surgery: A Case Series
We report a case series of five bariatric patients from a single institution who developed nephrogenic calciphylaxis between 2012-2018. These patients had a history of bariatric surgery and at the time of calciphylaxis diagnosis, demonstrated laboratory abnormalities associated with surgery including hypercalcemia (n=3), hyperparathyroidism (n=2), hypoalbuminemia (n=5), and vitamin D deficiency (n=5), in addition to other medication exposures such as vitamin D supplementation (n=2), calcium supplementation (n=4), warfarin (n=2), and intravenous iron (n=1). Despite the multifactorial etiology of calciphylaxis and the many r...
Source: American Journal of Nephrology - July 24, 2023 Category: Urology & Nephrology Authors: Joyce Xia Alice J Tan Bianca Biglione Bethany Cucka Lauren Ko Emily Nguyen Charbel C Khoury Malcolm Robinson Sagar U Nigwekar Daniela Kroshinsky Source Type: research

Quantitative Determination of Plasma Free and Total Concentrations of Antivitamin K Drugs Using a New Sensitive and Rapid LC-MS/MS Method: Application in Hemodialysis Patients
CONCLUSION: This opens the door to further studies to understand the factors involved in their variability.PMID:37482192 | DOI:10.1016/j.cca.2023.117498
Source: International Journal of Clinical Chemistry - July 23, 2023 Category: Chemistry Authors: Touria Mernissi Julien Demagny Mailys Le Guyader Marianne Renou Gabriel Choukroun Sa ïd Kamel Sophie Liabeuf Sandra Bodeau Source Type: research

Atypical Warfarin-Induced Calciphylaxis Outside a Typical Presentation of End-Stage Renal Disease on Hemodialysis
We present a case report highlighting a 47-year-old woman who developed warfarin-induced calciphylaxis. She initially developed bilateral leg wounds secondary to restraint straps from helicopter transportation to a higher level of care for treatment of critical aortic stenosis. She was started on warfarin following surgical implantation of a mechanical aortic valve. After her wounds failed to heal, a punch biopsy of the wounds demonstrated ulceration, altered vasculature, and soft tissue calcification. The pathology confirmed the clinical concern for calciphylaxis, which is most often diagnosed in patients with a history o...
Source: WMJ - March 20, 2023 Category: General Medicine Authors: Thomas Licata Jacob Elliot Ross Trecartin Adam Clements Source Type: research

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