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Drug: Methotrexate
Therapy: Corticosteroid Therapy
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Total 858 results found since Jan 2013.
Inflammation and immunomodulatory therapies influence the relationship between ATP-binding cassette A1 membrane transporter-mediated cholesterol efflux capacity and coronary atherosclerosis in rheumatoid arthritis
CONCLUSION: ABCA1-CEC associated with decreased atherosclerosis in patients with below-median baseline and time-averaged CRP and bDMARD use. Conversely, ABCA1-CEC associated with increased plaque in those with higher CRP, corticosteroid users, methotrexate nonusers, and bDMARD nonusers. While in well-treated and controlled disease ABCA1-CEC appears atheroprotective, in uncontrolled RA its action may be masked or fail to counteract the inflammation-driven proatherogenic state.PMID:37520890 | PMC:PMC10371792 | DOI:10.1016/j.jtauto.2023.100209
Source: Atherosclerosis - July 31, 2023 Category: Cardiology Authors: George A Karpouzas Bianca Papotti Sarah R Ormseth Marcella Palumbo Elizabeth Hernandez Maria Pia Adorni Francesca Zimetti Matthew J Budoff Nicoletta Ronda Source Type: research
Substitution of calcineurin inhibitors with corticosteroids after allogeneic hematopoietic cell transplantation
In conclusion, CIs were switched to corticosteroids in patients with severe clinical conditions. The incidence of acute GVHD was acceptable. Although the short-term mortality rate was high, improvement of renal function or fluid overload was observed in a certain proportion of the patients.PMID:37480446 | DOI:10.1007/s12185-023-03645-4
Source: International Journal of Hematology - July 22, 2023 Category: Hematology Authors: Shimpei Matsumi Shun-Ichi Kimura Yuhei Nakamura Masakatsu Kawamura Junko Takeshita Shunto Kawamura Nozomu Yoshino Yukiko Misaki Kazuki Yoshimura Ayumi Gomyo Yosuke Okada Yu Akahoshi Masaharu Tamaki Machiko Kusuda Kazuaki Kameda Hidenori Wada Aki Tanihara Source Type: research
Baricitinib retention rate: 'real-life' data from a mono-centric cohort of patients affected by rheumatoid arthritis
CONCLUSION: Our data show a good baricitinib retention rate after 12 and 24 months of observation (75.1 and 69.3%, respectively). In our cohort, concomitant treatment with methotrexate did not influence treatment persistence while retention was reduced in patients undergoing a steroidal treatment and/or in multi-failure subjects.PMID:37448804 | PMC:PMC10336222 | DOI:10.3389/fmed.2023.1176613
Source: Herpes - July 14, 2023 Category: Infectious Diseases Authors: Caterina Baldi Virginia Berlengiero Paolo Falsetti Alessandra Cartocci Edoardo Conticini Roberto D'Alessandro Emilio D'Ignazio Marco Bardelli Marta Fabbroni Luca Cantarini Bruno Frediani Stefano Gentileschi Source Type: research
Juvenile Dermatomyositis and Infantile Cerebral Palsy: Aicardi-Gouteres Syndrome, Type 5, with a Novel Mutation in SAMHD1-A Case Report
CONCLUSIONS: Early diagnosis of AGS is highly important as it allows starting treatment in a timely manner. Timely treatment, in return, can help avoid the development/progression of end-organ damage, including severe neurological complications and early death. It is necessary to spread information about AGS among neurologists, neonatologists, infectious disease specialists, and pediatricians. A multidisciplinary team approach is required.PMID:37371788 | DOI:10.3390/biomedicines11061693
Source: Herpes - June 28, 2023 Category: Infectious Diseases Authors: Lubov S Sorokina Rinat K Raupov Mikhail M Kostik Source Type: research
Psoriasis/Psoriatic Arthritis Patients' Long-term Treatment Patterns and Adherence to Systemic Treatments Monitoring Recommendations
Acta Derm Venereol. 2023 Jun 15;103:adv6505. doi: 10.2340/actadv.v103.6505.ABSTRACTLimited information exists regarding treatment of patients with psoriasis/psoriatic arthritis in primary care. The aim of this study is to assess treatment patterns, adherence, persistence, and compliance in newly diagnosed patients with psoriasis/psoriatic arthritis from 2012 to 2018 in Stockholm, Sweden. In addition, laboratory monitoring before initiation of treatment and at recommended intervals was quantified for patients prescribed methotrexate or biologics. A total of 51,639 individuals were included, with 39% initiating treatment wit...
Source: Acta Derm Venereol A... - June 15, 2023 Category: Dermatology Authors: Åsa Krantz Juan Jesus Carrero Yuanhang Yang Lovisa Schalin Josefin Lysell Faizan Mazhar Source Type: research
