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Specialty: Cytology
Drug: Acetic Acid

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Total 57 results found since Jan 2013.

Weissella koreensis and Pediococcus pentosaceus bacterial ghosts induce inflammatory responses as immunostimulants
In this study, bacterial ghosts (BGs) were generated from Weissella koreensis LKS42 (WKorGs) and Pediococcus pentosacues KA94 (PPGs) by chemically inducing lysis using substances such as hydrochloric acid (HCl), sulfuric acid (H2SO4), nitric acid (HNO3), acetic acid (CH3COOH), sodium hydroxide (NaOH), potassium hydroxide (KOH), sodium carbonate (Na2CO3), n-butanol, and C6H8O7. HCl-induced WKorGs and PPGs exhibited complete removal of DNA and displayed transverse membrane dissolution tunnel structures under scanning electron microscopy (SEM). Cell viability assays showed high viability of RAW 264.7 cells exposed to HCl-indu...
Source: Cell Research - August 19, 2023 Category: Cytology Authors: Jieun Lee Kwang-Su Lee Junwon Lee Ki-Sung Lee Shin-Young Park Source Type: research

< em > In vitro < /em > fermentation of glycosaminoglycans from mackerel fish waste and its role in modulating the antioxidant status and gut microbiota of high fat diet-fed C57BL/6 mice
Food Funct. 2023 Jul 18. doi: 10.1039/d2fo03603g. Online ahead of print.ABSTRACTBioactive polysaccharides such as glycosaminoglycans (GAGs) exhibit potential health benefits for several health complications including obesity. The gut microbiota plays a key role in regulating host metabolism, nutrition and immunity. The present work assessed the potential of extracted GAGs (e-GAGs) in maintaining the gut microbiota and ameliorating the effects of high fat diet in in vitro and in vivo models. The in vitro fermentability of e-GAGs extracted from mackerel fish waste was analyzed with Lactobacillus plantarum (LP) and Bifidobact...
Source: Cell Research - July 18, 2023 Category: Cytology Authors: Geetha V Chathur K N Smita Ramkumar Prakash M Halami Suresh Kumar G Source Type: research

Liuwei Anxiao San protects gastric mucosa from gastric ulcer in rats by regulating the JAK2/STAT3 pathway
In conclusion, LAS protects against gastric mucosal injury in GU rats through inhibition of oxidative stress and inflammation by suppressing the JAK2/STAT3 pathway.PMID:37437331 | DOI:10.1016/j.tice.2023.102145
Source: Tissue and Cell - July 12, 2023 Category: Cytology Authors: Ze Qu Dong Jiang Yan Liu Mingxing Hou Source Type: research

Regular Consumption of Biovalorized Okara-Containing Biscuit Improves Circulating Short-Chain Fatty Acids and Fecal Bile Acids Concentrations by Modulating the Gut Microbiome: A Randomized Controlled Crossover Trial
CONCLUSION: Okara consumption improved serum SCFA regardless of fermentation while biovalorised okara further enhanced gut metabolites by modulating gut microbiome. This article is protected by copyright. All rights reserved.PMID:37118978 | DOI:10.1002/mnfr.202200756
Source: Cell Research - April 29, 2023 Category: Cytology Authors: Delia Pei Shan Lee Alicia Xinli Gan Xue Juan Xia Kate Qi Xuan Toh Gregory Chan Sangyong Jung Jung Eun Kim Source Type: research

Inactivation of Listeria monocytogenes through the synergistic interaction between plasma-activated water and organic acid
This study observed that when plasma-activated water (PAW) was combined with organic acid, it showed a synergistic inactivation effect on Listeria monocytogenes, which is highly resistant to PAW. When comparing various organic acids, lactic acid (LA) showed the greatest synergistic effect, followed by malic acid (MA), citric acid (CA), and acetic acid (AA), whereas propionic acid (PA) did not show a synergistic effect. Organic acid lowered the activity of ROS defense enzymes (catalase, superoxide dismutase) by reducing intracellular pH (pHi), which induced the increase in the accumulation of ROS of PAW within the cell. In ...
Source: Cell Research - April 23, 2023 Category: Cytology Authors: Sunna Jyung Jun-Won Kang Dong-Hyun Kang Source Type: research

Chemical pancreatectomy in non-human primates ablates the acini and ducts and enhances beta-cell function
Res Sq. 2023 Mar 8:rs.3.rs-2618133. doi: 10.21203/rs.3.rs-2618133/v1. Preprint.ABSTRACTChronic pancreatitis is a debilitating disease affecting millions worldwide. These patients suffer from bouts of severe pain that are minimally relieved by pain medications and may necessitate major surgeries with high morbidity and mortality. Previously, we demonstrated that "chemical pancreatectomy," a pancreatic intraductal infusion of dilute acetic acid solution, ablated the exocrine pancreas while preserving the endocrine pancreas. Notably, chemical pancreatectomy resolved chronic inflammation, alleviated allodynia in the cerulein p...
Source: Cell Research - March 22, 2023 Category: Cytology Authors: Ranjeet S Kalsi Alexander M Kreger Mohamed Saleh Shiho Yoshida Kartikeya Sharma Joseph Fusco Jami L Saloman Ting Zhang Madison Thomas Anuradha Sehrawat Yan Wang Jason Reif Juliana Mills Sarah Raad Bugra Zengin Ana Gomez Aatur Singhi Sameh Tadros Adam Sliv Source Type: research

Characterization of procyanidin extracts from hawthorn (Crataegus pinnatifida) in human colorectal adenocarcinoma cell line Caco-2, simulated Digestion, and fermentation identified unique and novel prebiotic properties
This study aims to explore the dynamic changes of HPCs during in vitro digestion and fermentation, as well as their Caco-2 permeability, focusing mainly on the interaction between gut microbiota and HPCs. The results showed that the digested HPC samples had characteristic absorption peaks at 280 nm, and there were absorption peaks in the stretching vibration zone, including OH and CC on the benzene ring, which suggested that procyanidins were the main components in HPCs after in vitro digestion. Meanwhile, HPCs had the highest stability in the oral phase. However, the total procyanidin content of HPCs decreased during gast...
Source: Cell Research - March 4, 2023 Category: Cytology Authors: Xue Han Qian Zhou Zhe Gao Guanying Bianca Xu Hong Chen Bimal Chitrakar Yasai Sun Wen Zhao Xuan Lin Kaixuan Zhou Zhisheng Zhang Source Type: research

Effects of free fatty acid receptor-2 (FFAR2)-mediated signaling on the regulation of cellular functions in osteosarcoma cells
This study aimed to evaluate the roles of FFAR2 in the regulation of cellular functions in osteosarcoma HOS cells, using acetic acid and propanoic acid as FFAR2 and FFAR3 agonists. FFAR2 and FFAR3 genes were expressed in HOS cells. The cell motile activity of HOS cells was significantly stimulated by acetic acid and propanoic acid. In contrast, acetic acid and propanoic acid had no impact on the activation of matrix metalloproteinase-2 (MMP-2) and MMP-9. In cell survival assay, the cell survival rate to cisplatin (CDDP) of HOS cells was elevated by acetic acid and propanoic acid. To assess the effects of FFAR2 on cellular ...
Source: Cell Research - January 27, 2023 Category: Cytology Authors: Rio Kurisu Miwa Takai Miyu Takamoto Toshifumi Tsujiuchi Source Type: research

Tuning photosynthetic oxygen for hydrogen evolution in synergistically integrated, sulfur deprived consortia of Coccomyxa chodatii and Rhodobium gokarnense at dim and high light
Photosynth Res. 2022 Nov 23. doi: 10.1007/s11120-022-00961-4. Online ahead of print.ABSTRACTIn this work, tuning oxygen tension was targeted to improve hydrogen evolution. To achieve such target, various consortia of the chlorophyte Coccomyxa chodatii with a newly isolated photosynthetic purple non-sulfur bacterium (PNSB) strain Rhodobium gokarnense were set up, sulfur replete/deprived, malate/acetate fed, bicarbonate/sulfur added at dim/high light. C. chodatii and R. gokarnense are newly introduced to biohydrogen studies for the first time. Dim light was applied to avoid the inhibitory drawbacks of photosynthetic oxygen e...
Source: Cell Research - November 23, 2022 Category: Cytology Authors: Amal W Danial R Abdel-Basset Huwida A A Abdel-Kader Source Type: research

< em > VvSUN < /em > may act in the auxin pathway to regulate fruit shape in grape
Hortic Res. 2022 Sep 6;9:uhac200. doi: 10.1093/hr/uhac200. eCollection 2022.ABSTRACTFruit shape is an essential agronomic feature in many crops. We identified and functionally characterized an auxin pathway-related gene, VvSUN. VvSUN, which belongs to the SUN/IQ67-DOMAIN (IQD) family, localizes to the plasma membrane and chloroplast and may be involved in controlling fruit shape through auxin. It is highly expressed in the ovary, and the expression level 1 week before the anthesis stage is positively correlated with the fruit shape index. Functional analyses illustrated that VvSUN gene overexpression in tomato and tobacco ...
Source: Cell Research - November 16, 2022 Category: Cytology Authors: Huan Zheng Yang Dong Huilan Nong Liyuan Huang Jing Liu Xin Yu Yaguan Zhang Lina Yang Ben Hong Wu Wang Jianmin Tao Source Type: research

Indole-3-acetic acid improves the hepatic mitochondrial respiration defects by PGC1a up-regulation
In conclusion, our findings uncovered that I3A increased hepatic PGC1a expression, contributing to mitochondrial respiration improvement in NAFLD.PMID:35988807 | DOI:10.1016/j.cellsig.2022.110442
Source: Cellular Signalling - August 21, 2022 Category: Cytology Authors: Chen Zhang Qingsong Fu Kai Shao Limin Liu Xiaotian Ma Fengyi Zhang Xiaodong Zhang Liying Meng ChuanZhu Yan Xiaoyun Zhao Source Type: research

Multiscale modelling of mixotrophic algal growth in pilot-scale photobioreactors and its application to microalgal cultivation using wastewater
Environ Res. 2022 Aug 4:113952. doi: 10.1016/j.envres.2022.113952. Online ahead of print.ABSTRACTThis multiscale model quantifies transport and reaction processes in mixotrophic microalgal growth at three characteristic length scales, namely, macro (photobioreactor), meso (algal cell), micro (organelles). The macro and the meso scale equations capture the temporal dynamics of the transport of CO2, O2, H+, organic carbon and nitrogen sources in the photobioreactor and the cell, respectively, while the micro scale quantifies the reaction rates of CO2 fixation and photorespiration in the chloroplast, and mitochondrial respira...
Source: Cell Research - August 7, 2022 Category: Cytology Authors: Arun Kumar Mehta Saikat Chakraborty Source Type: research