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Drug: Acetic Acid
Procedure: MRI Scan
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Total 43 results found since Jan 2013.
Unexpected Ocular Manifestations Due to Exposure to Highly Concentrated Peracetic Acid: A Case Report
CONCLUSIONS Until now, there have been no published studies demonstrating neuritis caused by direct contact of peracetic acid into the eyes. Therefore, this is the first report in the world literature of this manifestation of ocular exposure to peracetic acid. This is a chemical formulation that is widely useful and prevents the growth of various pathogens. Further investigation and studies on the subject should be encouraged to improve its management and use.PMID:37287216 | DOI:10.12659/AJCR.940114
Source: Herpes - June 8, 2023 Category: Infectious Diseases Authors: Luiz William L S Cavalcanti Antonio Brunno V Nepomuceno Juliana de Lucena Martins Ferreira Source Type: research
Acute hydrogen sulfide-induced neurochemical and morphological changes in the brainstem
Toxicology. 2023 Jan 4:153424. doi: 10.1016/j.tox.2023.153424. Online ahead of print.ABSTRACTHydrogen sulfide (H2S) is a toxin affecting the cardiovascular, respiratory, and central nervous systems. Acute H2S exposure is associated with a high rate of mortality and morbidity. The precise pathophysiology of H2S-induced death is a controversial topic; however, inhibition of the respiratory center in the brainstem is commonly cited as a cause of death. There is a knowledge gap on toxicity and toxic mechanisms of acute H2S poisoning on the brainstem, a brain region responsible for regulating many reflective and vital functions...
Source: Toxicology - January 7, 2023 Category: Toxicology Authors: Cristina M Santana Maldonado Dong-Suk Kim Benton Purnell Rui Li Gordon F Buchanan Jodi Smith Daniel R Thedens Phillip Gauger Wilson K Rumbeiha Source Type: research
An activatable Mn(II) MRI probe for detecting peroxidase activity in vitro and in vivo
In this study, an activatable Mn(II) chelate-based magnetic resonance imaging (MRI) contrast agent (CA), Mn-TyEDTA (TyEDTA = tyrosine derived ethylenediaminetetraacetic acid) structurally featuring a phenol group as the electron-donor, was developed to sense the activity of peroxidase in vitro and in vivo. Mn-TyEDTA demonstrated a peroxidase activity-dependent relaxivity in the presence of horseradish peroxidase (HRP)/H2O2 with more than a 2.6-fold increase in water proton relaxivity produced (HRP, 500 U; H2O2, 4.5 eq). A mechanism of peroxidase-mediated Mn(II) monomer radical polymerization was confirmed with those oligom...
Source: Journal of Inorganic Biochemistry - September 10, 2022 Category: Biochemistry Authors: Yunhe Li Qian Xia Chunrong Zhu Weidong Cao Zhiyang Xia Xinxin Liu Bin Xiao Keyu Chen Yun Liu Lei Zhong Bangxian Tan Jun Lei Jiang Zhu Source Type: research
Mapping single nephron filtration in the isolated, perfused rat kidney using magnetic resonance imaging
Am J Physiol Renal Physiol. 2022 Sep 1. doi: 10.1152/ajprenal.00103.2022. Online ahead of print.ABSTRACTThe kidney has an extraordinary ability to maintain glomerular filtration despite natural fluctuations in blood pressure or nephron loss. This is partly due to local coordination between single nephron filtration and vascular perfusion. An improved understanding of the three-dimensional functional coordination between nephrons and the vasculature may provide a new perspective of the heterogeneity of kidney function and could inform targeted therapies and timed interventions to slow or prevent the progression of kidney di...
Source: American Journal of Physiology. Renal Physiology - September 1, 2022 Category: Physiology Authors: Edwin J Baldelomar Jennifer R Charlton Kevin M Bennett Source Type: research
