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A Copernican Approach to Brain Advancement: The Paradigm of Allostatic Orchestration
The objective of this presentation is to explore historical, scientific, interventional, and other differences between the two paradigms, so that innovators, researchers, practitioners, policy-makers, patients, end-users, and others can gain clarity with respect to both the explicit and implicit assumptions associated with brain advancement agendas of any kind. Over the course of three decades, a series of brain-centric, evolution-inspired insights have been articulated with increasing refinement, as principles of allostasis (Sterling and Eyer, 1988; Sterling, 2004, 2012, 2014). Allostasis recognizes that the role of the ...
Source: Frontiers in Human Neuroscience - April 25, 2019 Category: Neuroscience Source Type: research

< em > Angelica gigas < /em > : Signature Compounds, < em > In Vivo < /em > Anticancer, Analgesic, Neuroprotective and Other Activities, and the Clinical Translation Challenges
Am J Chin Med. 2022 Jul 23:1-53. doi: 10.1142/S0192415X2250063X. Online ahead of print.ABSTRACTAngelica gigas Nakai (AGN) root is a medicinal herbal widely used in traditional medicine in Korea. AGN root ethanolic extract dietary supplements are marketed in the United States for memory health and pain management. We comprehensively reviewed the anticancer, analgesic, pro-memory and other bio-activities of AGN extract and its signature phytochemicals decursin, decursinol angelate, and decursinol a decade ago in 2012 and updated their anticancer activities in 2015. In the last decade, significant progress has been made for u...
Source: The American Journal of Chinese Medicine - July 25, 2022 Category: Complementary Medicine Authors: Junxuan L ü Cheng Jiang Todd D Schell Monika Joshi Jay D Raman Chengguo Xing Source Type: research