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Drug: Aspirin
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Total 81 results found since Jan 2013.
Compliance-adjusted estimates of aspirin effects in older persons in the ASPREE randomized trial
Am J Epidemiol. 2023 Aug 8:kwad168. doi: 10.1093/aje/kwad168. Online ahead of print.ABSTRACTThe ASPirin in Reducing Events in the Elderly (ASPREE) trial recruited 19,114 participants across Australia and the United States during 2010-14. Participants were randomized to receive either 100mg aspirin daily or matching placebo, with disability-free survival as the primary outcome. During a median 4.7 years of follow-up, 37% of participants in the aspirin group permanently ceased taking their study medication and 10% commenced open label aspirin (OLA). In the placebo group, 35% and 11% ceased study medication and commenced OLA,...
Source: Am J Epidemiol - August 8, 2023 Category: Epidemiology Authors: C L Smith J Kasza R L Woods J E Lockery B Kirpach C M Reid E Storey M R Nelson R C Shah S G Orchard M E Ernst A M Tonkin A M Murray J J McNeil R Wolfe Source Type: research
Effect of Low-Dose Aspirin Versus Placebo on Incidence of Anemia in the Elderly : A Secondary Analysis of the Aspirin in Reducing Events in the Elderly Trial
CONCLUSION: Low-dose aspirin increased incident anemia and decline in ferritin in otherwise healthy older adults, independent of major bleeding. Periodic monitoring of hemoglobin should be considered in older persons on aspirin.PRIMARY FUNDING SOURCE: National Institutes of Health and Australian National Health and Medical Research Council.PMID:37335992 | DOI:10.7326/M23-0675
Source: Annals of Internal Medicine - June 19, 2023 Category: Internal Medicine Authors: Zoe K McQuilten Le Thi Phuong Thao Sant-Rayn Pasricha Andrew S Artz Michael Bailey Andrew T Chan Harvey Jay Cohen Jessica E Lockery Anne M Murray Mark R Nelson Hans G Schneider Rory Wolfe Robyn L Woods Erica M Wood John J McNeil Source Type: research
Contemporary Antiplatelet and Anticoagulant Therapies for Secondary Stroke Prevention: A Narrative Review of Current Literature and Guidelines
Curr Neurol Neurosci Rep. 2023 Apr 11. doi: 10.1007/s11910-023-01266-2. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Stroke is a leading cause of death and disability worldwide. The annual incidence of new or recurrent stroke is approximately 795,000 cases per year in the United States, of which 87% are ischemic in nature. In addition to the management of modifiable high-risk factors to reduce the risk of recurrent stroke, antithrombotic agents (antiplatelets and anticoagulants) play an important role in secondary stroke prevention. This review will discuss the published literature on the use of antiplatelets and antic...
Source: Atherosclerosis - April 10, 2023 Category: Cardiology Authors: Kunal Bhatia Lindsey M Ladd Kelsey H Carr Mario Di Napoli Jeffrey L Saver Louise D McCullough Maryam Hosseini Farahabadi Diana L Alsbrook Archana Hinduja Jorge G Ortiz Garcia Sara Y Sabbagh Alibay Jafarli Afshin A Divani Source Type: research
Effect of Antiplatelet and Anticoagulant Agents on Outcomes Following Emergent Surgery for Traumatic Brain Injuries
CONCLUSION: Patients on AP/AC who experience a TBI requiring an emergent operation do not have an increased risk of mortality compared to patients not on AP/AC.PMID:36786276 | DOI:10.1177/00031348231157412
Source: The American Surgeon - February 14, 2023 Category: Surgery Authors: Rola Bazzi Victoria Sharp Jason Hecht Source Type: research
Appropriateness of aspirin use among diabetic patients in primary prevention of atherosclerotic cardiovascular diseases: an analysis of the ASSOS study
CONCLUSIONS: Inappropriate aspirin use was common among diabetic patients, according to clinical practice guideline recommendations. In addition, the differences between the indications for the use of aspirin in diabetic patients according to the guidelines were remarkable. Guidelines that minimize these differences are needed for clinicians, and compliance with these guidelines in clinical practice could reduce inappropriate aspirin use.PMID:36647878 | DOI:10.26355/eurrev_202301_30877
Source: Pharmacological Reviews - January 17, 2023 Category: Drugs & Pharmacology Authors: E Demirci O Celik C Cil V O Tan ık K Memic Sancar O Orscelik M M Resulzade C Kaya T K ırıs V Dogan O Basaran Source Type: research
