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Therapy: Neoadjuvant Chemotherapy Therapy
Countries: UK Health
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Total 195 results found since Jan 2013.
Neoadjuvant chemotherapy for advanced colonic cancer: standard of care or is the jury still out?
Br J Surg. 2023 Sep 19:znad281. doi: 10.1093/bjs/znad281. Online ahead of print.NO ABSTRACTPMID:37724780 | DOI:10.1093/bjs/znad281
Source: The British Journal of Surgery - September 19, 2023 Category: Surgery Authors: Peter G Vaughan-Shaw Martyn D Evans Source Type: research
The assessment of pathological response to neoadjuvant chemotherapy in muscle-invasive bladder cancer patients with DCE-MRI and DWI: a systematic review and meta-analysis
CONCLUSION: This meta-analysis demonstrated high diagnostic performance of both DCE-MRI and DWI in predicting the pathological response to NAC in MIBC. DWI might be a potential substitute for DCE-MRI, with no significant difference in diagnostic performance between the two. However, caution should be taken when applying our results, as our results were based on indirect comparison.ADVANCES IN KNOWLEDGE: No previous studies have comprehensively analysed the value of DCE-MRI and DWI in evaluating the pathological response to NAC in MIBC. According to the current study, both DCE-MRI and DWI yielded high diagnostic performance...
Source: The British Journal of Radiology - September 3, 2023 Category: Radiology Authors: Ruilong Zong Xijuan Ma Yibing Shi Li Geng Source Type: research
Targeting carcinoma-associated mesothelial cells with antibody-drug conjugates in ovarian carcinomatosis
J Pathol. 2023 Aug 9. doi: 10.1002/path.6170. Online ahead of print.ABSTRACTOvarian carcinomatosis is characterized by the accumulation of carcinoma-associated mesothelial cells (CAMs) in the peritoneal stroma and mainly originates through a mesothelial-to-mesenchymal transition (MMT) process. MMT has been proposed as a therapeutic target for peritoneal metastasis. Most ovarian cancer (OC) patients present at diagnosis with peritoneal seeding, which makes tumor progression control difficult by MMT modulation. An alternative approach is to use antibody-drug conjugates (ADCs) targeted directly to attack CAMs. This strategy c...
Source: Cancer Control - August 9, 2023 Category: Cancer & Oncology Authors: Luc ía Pascual-Antón Pilar Sandoval Guadalupe T Gonz ález-Mateo Valeria Kopytina Henar Tomero-Sanz Eva Mar ía Arriero-País Jos é Antonio Jiménez-Heffernan Myriam Fabre Isabel Ega ña Cristina Ferrer Laureano Sim ón Luc ía González-Cortijo Ricard Source Type: research
Predictive value of baseline serum carbohydrate antigen 19-9 level on treatment effect of neoadjuvant chemoradiotherapy in patients with resectable and borderline resectable pancreatic cancer in two randomized trials
CONCLUSION: Baseline serum CA19-9 level defined as either high or low has prognostic value, but was not associated with the treatment effect of neoadjuvant CRT in patients with resectable and borderline resectable pancreatic cancers, in contrast with current guideline advice.PMID:37440421 | DOI:10.1093/bjs/znad210
Source: The British Journal of Surgery - July 13, 2023 Category: Surgery Authors: Deesje Doppenberg Jacob L van Dam Youngmin Han Bert A Bonsing Olivier R Busch Sebastiaan Festen Erwin van der Harst Ignace H de Hingh Marjolein Y V Homs Wooil Kwon Mirang Lee Daan J Lips Vincent E de Meijer I Quintus Molenaar Joost J Nuyttens Gijs A Patij Source Type: research
Active surveillance of oesophageal cancer after response to neoadjuvant chemoradiotherapy: dysphagia is uncommon
CONCLUSION: Dysphagia and clinically relevant stenosis are uncommon during active surveillance.PMID:37418342 | DOI:10.1093/bjs/znad211
Source: The British Journal of Surgery - July 7, 2023 Category: Surgery Authors: Maria J Valkema Manon C W Spaander Jurjen J Boonstra Jolanda M van Dieren Wouter L Hazen G Willemien Erkelens I Lisanne Holster Andries van der Linden Klaas van der Linde Liekele E Oostenbrug Rutger Quispel Erik J Schoon Peter D Siersema Michail Doukas Be Source Type: research
Locally recurrent rectal cancer: oncological outcomes of neoadjuvant chemoradiotherapy with or without induction chemotherapy
Br J Surg. 2023 Jul 5:znad214. doi: 10.1093/bjs/znad214. Online ahead of print.NO ABSTRACTPMID:37406084 | DOI:10.1093/bjs/znad214
Source: The British Journal of Surgery - July 5, 2023 Category: Surgery Authors: Stefi Nordkamp Jan M van Rees Kim van den Berg David M Mens Davy M J Creemers Heike M U Peulen Geert-Jan Creemers Grard A P Nieuwenhuijzen Jip L Tolenaar Johanne G Bloemen Joost Rothbarth Harm J T Rutten Cornelis Verhoef Jacobus W A Burger Source Type: research
Predicting the response to neoadjuvant chemotherapy. Can the addition of tomosynthesis improve the accuracy of contrast-enhanced spectral mammography? A comparison with breast MRI
CONCLUSIONS: CESM is similar to MRI for predicting residual disease post-NACT. Size of enhancement alone demonstrates best concordance with invasive disease. Inclusion of residual microcalcification improves concordance with ductal carcinoma in situ. The addition of DBT to CESM does not improve accuracy.ADVANCES IN KNOWLEDGE: The addition ofDBT to CESM does not improve NACT response prediction.CESM enhancement has greatest accuracy for residual invasive disease, CESM+calcification has greater accuracy for residual in situ disease.PMID:37399083 | DOI:10.1259/bjr.20220921
Source: The British Journal of Radiology - July 3, 2023 Category: Radiology Authors: Sarah L Savaridas Sarah J Vinnicombe Violet Warwick Andrew Evans Source Type: research
Total neoadjuvant therapy versus standard neoadjuvant treatment strategies for the management of locally advanced rectal cancer: network meta-analysis of randomized clinical trials
CONCLUSION: This study provides further evidence that TNT has improved survival and recurrence benefits compared with current standards of care, and may increase the number of patients suitable for organ preservation, without negatively influencing treatment toxicity or compliance.PMID:37330950 | DOI:10.1093/bjs/znad177
Source: The British Journal of Surgery - June 18, 2023 Category: Surgery Authors: Mark Donnelly Odhr án K Ryan Éanna J Ryan Ben Creavin Mary O'Reilly Ray McDermott Rory Kennelly Ann Hanly Se án T Martin Des C Winter Source Type: research
