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The Effect of the ABCB1(MDR-1) C3435T Polymorphism in Turkish Patients with Aspirin Resistance in Acute Ischemic Stroke
This study aimed to investigate the rate of AR, the factors influencing AR in patients with acute ischemic stroke under regular aspirin use, and the relationship between AR and ABCB1 (MDR-1) C3435T (rs1045642) polymorphism. Throughout this multicenter prospective study, 174 patients with acute ischemic stroke who had been prescribed aspirin for at least one month due to the risk of vascular disease, along with 106 healthy volunteers, were included as part of the study group. The results of our study indicate that AR was detected in 21.3% of the patient group. According to the results of an analysis of the polymorphism of t...
Source: Translational Stroke Research - July 11, 2023 Category: Neurology Source Type: research

Baseline characteristics predicting clinical outcomes and serious adverse events in middle-aged hypertensive women: a sub-analysis of the SPRINT in women aged < 65 years.
CONCLUSION: Smoking, aspirin, CKD, black race, and age seemed as important baseline characteristics in follow-up of <65-year-old hypertensive women, also depending on therapeutic strategy. Clinicians are expected to consider these critical parameters for effective antihypertensive management that promotes better outcomes in this middle-aged female population. PMID: 32490642 [PubMed - as supplied by publisher]
Source: Turkish Journal of Medical Sciences - June 4, 2020 Category: General Medicine Tags: Turk J Med Sci Source Type: research

Global Trends in Aspirin Resistance ‐Related Research from 1990 to 2015: A Bibliometric Analysis
This study presents the results of the first bibliometric study (including quantitative and qualitative analysis) of scientific publications in the field of aspirin renitence at global level. Aspirin resistance‐related researches have notably increased in the last years, especially from 2000 to 2015. The USA is the most prolific country, not only in research quantity but also in quality. Furthermore, Turkey and European countries provided more research related to aspirin resistance than other regions such as the developing countries. This article is protected by copyright. All rights reserved.
Source: Basic and Clinical Pharmacology and Toxicology - June 1, 2017 Category: Drugs & Pharmacology Authors: Samah W. Al ‐Jabi Tags: Original Article Source Type: research

Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study.
Conclusion: These results demonstrate the necessity for improved quality of physician care of patients with AF, especially with regards to antithrombotic therapy. PMID: 23666295 [PubMed - in process]
Source: Turk Kardiyoloji Dernegi arsivi - March 1, 2013 Category: Cardiology Authors: Ertaş F, Kaya H, Kaya Z, Bulur S, Köse N, Gül M, Kahya Eren N, Cağlıyan CE, Köroğlu B, Vatan B, Acar G, Yüksel M, Bilik MZ, Gedik S, Simşek Z, Akıl MA, Yılmaz R, Oylumlu M, Arıbaş A, Yıldız A, Aydın M, Yeter E, Kanadaşı M, Ergene O, Ozha Tags: Turk Kardiyol Dern Ars Source Type: research