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Total 5273 results found since Jan 2013.

Electrolytes Play a Role in Detecting Cisplatin-Induced Kidney Complications and May Even Prevent Them-Retrospective Analysis
Conclusions: We report that an average of 15% of patients with electrolyte abnormalities develop renal toxicity and reduced function. Moreover, electrolytes may serve as an early indicator for renal damage as part of chemotherapy complication. This indication represents 15% of renal toxicity cases. Changes in electrolyte levels have been reported with cisplatin. Specifically, it has been linked to hypomagnesemia, hypocalcemia and hypokalemia. This study will help reduce the risk of dialysis or the need for kidney transplant. It is also important to manage any underlying conditions and control patients' intake of electrolyt...
Source: Cancer Control - May 27, 2023 Category: Cancer & Oncology Authors: Bahauddeen M Alrfaei Abdulaziz O Almutairi Alaa A Aljohani Hajar Alammar Abdulaziz Asiri Yahya Bokhari Feda S Aljaser Manal Abudawood Majed Halwani Source Type: research

Acute kidney injury in Coronavirus disease-19 related pneumonia in the intensive care unit: a retrospective multicenter study, Saudi Arabia
CONCLUSION: AKI is common in adults admitted to the ICU with COVID-19 and is associated with an increased risk of death. Early detection of AKI and appropriate treatment can positively impact COVID-19 outcome. CRRT is the preferred dialysis method in critically ill ICU patients with AKI.PMID:36936197 | PMC:PMC10015944 | DOI:10.4081/mrm.2023.895
Source: Respiratory Care - March 20, 2023 Category: Respiratory Medicine Authors: Safwat A M Eldaboosy Amgad Awad Abdullah Farouk Waheed Mahdy Eman Abdelsalam Sameh O Nour Ahmed Kabil Ahmad Taha Sameh Makled Ahmed Lotfi Usama Nabway Hatem Kanany Source Type: research

Outsourcing Dialysis Program: Implementation and Challenges
Saudi J Kidney Dis Transpl. 2022 Jan-Feb;33(1):160-167. doi: 10.4103/1319-2442.367809.ABSTRACTThe demand for dialysis treatment has exceeded supply over the last decade in Saudi Arabia in line with other countries in the region and hence the Ministry of Health (MOH) to outsource dialysis care on a fee-for-service basis. The main objective of this review article is to examine and understand the challenges and strategies devised for the successful implementation, the good operation, and the guaranteed efficiency of outsourcing dialysis program in order to achieve the set clinical performance indicators and quality standards....
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Ali Alharbi Imed Helal Mohammed Alhomrany Fayez Alhejaili Dujanah Mousa Source Type: research

Living Experiences with Maintenance Hemodialysis: A Qualitative Content Analysis
In this study, a dual face was seen in HD in the eyes of these patients. Therefore, "dual face HD therapy" was identified as the essence of the experiences of HD patients. Health-care providers should try to eliminate the bad and unpleasant face of HD.PMID:36647982 | DOI:10.4103/1319-2442.367829
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Hosnieh Miri Mozhgan Rahnama Mahin Naderifar Source Type: research

Hepatocyte Growth Factor in Predialysis and Hemodialysis Chronic Kidney Disease Patients
Saudi J Kidney Dis Transpl. 2022 Jan-Feb;33(1):58-65. doi: 10.4103/1319-2442.367826.ABSTRACTChronic kidney disease (CKD) which is characterized by progressive loss of renal function and renal fibrosis is a worldwide public health problem. Hepatocyte growth factor (HGF) is a polypeptide that exhibits multiple functions including antifibrotic effects on kidneys. The present study was aimed at evaluating HGF levels and studying its association with markers of inflammation and oxidative stress in patients of predialysis and dialysis CKD. A total of 80 subjects including 20 healthy controls, 40 patients of CKD stage 1 to stage ...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Sarat Chandra Vulugundam Vinapamula S Kiranmayi P V L N Srinivasa Rao Siva Kumar Vishnubhotla Source Type: research

Does the Prolonged Duration of Continuous Ambulatory Peritoneal Dialysis Affect the Serum Levels of Endothelin-1 and Nitric Oxide?
This study included 23 uremic patients [10 males, mean age: 56.3 (±16.2) years] treated with CAPD. All studied patients were further divided into subgroups, groups A and B. Group A included patients on treatment with CAPD <5 years, and group B included those on treatment longer than five years. Our results showed that serum levels of these vasoactive substances are significantly higher among patients treated with CAPD longer than five years (ET-1: 51.24 ± 32.11 vs. 139.53 ± 42.42; NO: 15.50 ± 2.57 vs. 26.57 ± 5.96, respectively). We concluded that imbalance in production of vasoactive substances is present in long-...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Pedja Kovacevic Sasa Dragic Tijana Kovacevic Biljana Zlojutro Milka Jandric Danica Momcicevic Source Type: research

Clinical Characteristics and Outcomes of Coronavirus Disease 2019 Infection of In-center Hemodialysis Patients: An Experience of a Dialysis Center from Pakistan
Saudi J Kidney Dis Transpl. 2022 Jan-Feb;33(1):16-30. doi: 10.4103/1319-2442.367808.ABSTRACTMuch has now been learned about the coronavirus disease 2019 (COVID-19) in the general population, but data for hemodialysis (HD) patients are limited. This is the first study of COVID-19 disease in patients undergoing maintenance HD in Pakistan. We studied the epidemiological, clinical, laboratory, radiological characteristics, and outcomes of a cohort of HD patients that contracted COVID-19 in our HD center from the first confirmed case on May 12, 2020, until September 9, 2020. Out of the total 423 patients being dialyzed in our c...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Shabana Rahim Murtaza F Dhrolia Kiran Nasir Ruqaya Qureshi Aasim Ahmed Source Type: research

Study of Exogenous Melatonin as a Treatment Modality for Sleep and Psychiatric Disorders in Hemodialysis Patients
This study showed a significant improvement in serum calcium, low-density lipoprotein level (P ≤0.005), and scores of HDRS, HARS, and total QLI in the melatonintreated group (P ≤0.001, 0.001, and 0.002, respectively). Moreover, there was a highly significant improvement in sleep disorders in melatonin-treated patients regarding total score of PSQI, ISI, subjective sleep quality, and daytime dysfunction (P ≤0.001), also regarding sleep duration, latency, and disturbances (P ≤0.05). However, there was no significant difference in sleep efficiency and ESS scores. Exogenous melatonin treatment was well-tolerated, safe,...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Elshahat Ali Yousef Mahmoud Ahmed El Wasify Aya Atef Baddor Mohammed Abd-Elkader Sobh Source Type: research

Outsourcing Dialysis Program: Implementation and Challenges
Saudi J Kidney Dis Transpl. 2022 Jan-Feb;33(1):160-167. doi: 10.4103/1319-2442.367809.ABSTRACTThe demand for dialysis treatment has exceeded supply over the last decade in Saudi Arabia in line with other countries in the region and hence the Ministry of Health (MOH) to outsource dialysis care on a fee-for-service basis. The main objective of this review article is to examine and understand the challenges and strategies devised for the successful implementation, the good operation, and the guaranteed efficiency of outsourcing dialysis program in order to achieve the set clinical performance indicators and quality standards....
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Ali Alharbi Imed Helal Mohammed Alhomrany Fayez Alhejaili Dujanah Mousa Source Type: research

Living Experiences with Maintenance Hemodialysis: A Qualitative Content Analysis
In this study, a dual face was seen in HD in the eyes of these patients. Therefore, "dual face HD therapy" was identified as the essence of the experiences of HD patients. Health-care providers should try to eliminate the bad and unpleasant face of HD.PMID:36647982 | DOI:10.4103/1319-2442.367829
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Hosnieh Miri Mozhgan Rahnama Mahin Naderifar Source Type: research

Hepatocyte Growth Factor in Predialysis and Hemodialysis Chronic Kidney Disease Patients
Saudi J Kidney Dis Transpl. 2022 Jan-Feb;33(1):58-65. doi: 10.4103/1319-2442.367826.ABSTRACTChronic kidney disease (CKD) which is characterized by progressive loss of renal function and renal fibrosis is a worldwide public health problem. Hepatocyte growth factor (HGF) is a polypeptide that exhibits multiple functions including antifibrotic effects on kidneys. The present study was aimed at evaluating HGF levels and studying its association with markers of inflammation and oxidative stress in patients of predialysis and dialysis CKD. A total of 80 subjects including 20 healthy controls, 40 patients of CKD stage 1 to stage ...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Sarat Chandra Vulugundam Vinapamula S Kiranmayi P V L N Srinivasa Rao Siva Kumar Vishnubhotla Source Type: research

Does the Prolonged Duration of Continuous Ambulatory Peritoneal Dialysis Affect the Serum Levels of Endothelin-1 and Nitric Oxide?
This study included 23 uremic patients [10 males, mean age: 56.3 (±16.2) years] treated with CAPD. All studied patients were further divided into subgroups, groups A and B. Group A included patients on treatment with CAPD <5 years, and group B included those on treatment longer than five years. Our results showed that serum levels of these vasoactive substances are significantly higher among patients treated with CAPD longer than five years (ET-1: 51.24 ± 32.11 vs. 139.53 ± 42.42; NO: 15.50 ± 2.57 vs. 26.57 ± 5.96, respectively). We concluded that imbalance in production of vasoactive substances is present in long-...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Pedja Kovacevic Sasa Dragic Tijana Kovacevic Biljana Zlojutro Milka Jandric Danica Momcicevic Source Type: research

Clinical Characteristics and Outcomes of Coronavirus Disease 2019 Infection of In-center Hemodialysis Patients: An Experience of a Dialysis Center from Pakistan
Saudi J Kidney Dis Transpl. 2022 Jan-Feb;33(1):16-30. doi: 10.4103/1319-2442.367808.ABSTRACTMuch has now been learned about the coronavirus disease 2019 (COVID-19) in the general population, but data for hemodialysis (HD) patients are limited. This is the first study of COVID-19 disease in patients undergoing maintenance HD in Pakistan. We studied the epidemiological, clinical, laboratory, radiological characteristics, and outcomes of a cohort of HD patients that contracted COVID-19 in our HD center from the first confirmed case on May 12, 2020, until September 9, 2020. Out of the total 423 patients being dialyzed in our c...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Shabana Rahim Murtaza F Dhrolia Kiran Nasir Ruqaya Qureshi Aasim Ahmed Source Type: research

Study of Exogenous Melatonin as a Treatment Modality for Sleep and Psychiatric Disorders in Hemodialysis Patients
This study showed a significant improvement in serum calcium, low-density lipoprotein level (P ≤0.005), and scores of HDRS, HARS, and total QLI in the melatonintreated group (P ≤0.001, 0.001, and 0.002, respectively). Moreover, there was a highly significant improvement in sleep disorders in melatonin-treated patients regarding total score of PSQI, ISI, subjective sleep quality, and daytime dysfunction (P ≤0.001), also regarding sleep duration, latency, and disturbances (P ≤0.05). However, there was no significant difference in sleep efficiency and ESS scores. Exogenous melatonin treatment was well-tolerated, safe,...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Elshahat Ali Yousef Mahmoud Ahmed El Wasify Aya Atef Baddor Mohammed Abd-Elkader Sobh Source Type: research