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Total 2168 results found since Jan 2013.

Stroke Mimics and Accuracy of Referrals Made by Emergency Department Doctors in Japan for Patients with Suspected Stroke
Background: Stroke mimics (SMs)are medical conditions that are at first considered to be of cerebrovascular etiology but turn out to be a condition other than stroke. While many reports on SMs have been published, there have been none from Japan. Thus, we sought to assess the current state of SMs in a Japanese population. Methods: We collected data of patients referred with suspicion of stroke to neurosurgeons by emergency department (ED) doctors, and we retrospectively evaluated the diagnosis concordance rate between the ED doctors and the neurosurgeons.
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2019 Category: Neurology Authors: Narushi Sugii, Alexander Zaboronok, Hiroyuki Fujimori, Naoaki Sato, Keishi Fujita, Eiichi Ishikawa, Akira Matsumura Source Type: research

Association between Angiotensin-Converting Enzyme Inhibitors and Post-Stroke Aspiration Pneumonia
This study aimed to re-evaluate the preventive effect of ACEIs on post-stroke AP, compared with that of angiotensin II receptor blockers (ARBs).
Source: Journal of Stroke and Cerebrovascular Diseases - October 17, 2019 Category: Neurology Authors: Ryosuke Kumazawa, Taisuke Jo, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga Source Type: research

Stroke Systems of Care during the COVID-19 Epidemic in Kobe City
The novel coronavirus disease 2019  (COVID-19), first reported in Wuhan, China, in December 2019, spread worldwide in 2020. As of June 1, 2020, the estimated number of global cases and deaths has exceeded 6 million and 370,000, respectively.1 In Japan, the number of reported cases increased sharply in March 2020, with community tran smission presenting at the highest rate in urban areas, leading to a state of emergency being declared by the Japanese government on April 7. Subsequently, on April 9, the Japan Stroke Society and the Japanese Circulation Society issued a joint statement on the importance of maintaining high-q...
Source: Journal of Stroke and Cerebrovascular Diseases - September 29, 2020 Category: Neurology Authors: Nobuyuki Ohara, Hirotoshi Imamura, Hidemitsu Adachi, Yoshie Hara, Kohkichi Hosoda, Hidehito Kimura, Kazuyuki Kuwayama, Takashi Mizowaki, Yasuhiko Motooka, Kazuya Nakashima, Narihide Shinoda, Takeshi Takamoto, Yasushi Ueno, Ikuya Yamaura, Chie Yanagihara, Source Type: research

Clinical Features for Identifying the Possibility of Toileting Independence after Convalescent Inpatient Rehabilitation in Severe Stroke Patients: A Decision Tree Analysis Based on a Nationwide Japan Rehabilitation Database
This study aimed to identify the factors affecting toileting independence in severe stroke patients using ML.
Source: Journal of Stroke and Cerebrovascular Diseases - November 27, 2020 Category: Neurology Authors: Takeshi Imura, Yu Inoue, Ryo Tanaka, Junji Matsuba, Yasutaka Umayahara Source Type: research

Cost-Effectiveness Analysis of Percutaneous Patent Foramen Ovale Closure Preventing Secondary Ischemic Stroke in Japan
Cryptogenic ischemic stroke is a type of ischemic stroke for which the mechanism of onset and etiology cannot be explained or specified by any known mechanisms/factors. The possible involvement of patent foramen ovale (PFO) in the etiology of cryptogenic ischemic stroke has been reported.1 It was previously reported that occult atrial fibrillation and PFO were embolic sources that caused cryptogenic ischemic stroke.2 PFO is an opening formed during the course of fetal atrial septum development. Usually, it closes spontaneously after birth; however, PFO remains patent after maturation to adulthood.
Source: Journal of Stroke and Cerebrovascular Diseases - June 18, 2021 Category: Neurology Authors: Sachie Inoue, Ataru Igarashi, Yasuyuki Iguchi, Teiji Akagi Source Type: research

Association Between Oral Anticoagulants and Stroke Severity at Onset in Elderly Patients with Cardioembolic Stroke Due to Non-Valvular Atrial Fibrillation
The prevention of cardioembolic stroke is an important public health priority in Japan due to its high prevalence in elderly individuals. Compared to their younger counterparts, elderly patients with cardioembolic stroke are more likely to have multiple comorbidities, a higher risk of serious complications, such as pneumonia and heart failure, and cognitive impairments (e.g., dementia or delirium), which may adversely affect their ability to participate in active rehabilitation. These factors negatively affect clinical outcomes, and many elderly stroke survivors require long-term care despite the early implementation of intensive therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - December 25, 2021 Category: Neurology Authors: Ichiro Deguchi, Takashi Osada, Shinichi Takahashi Source Type: research

Relationship between Alcohol Intake and Stroke Severity in Japanese Patients: a Sex- and Subtype-Stratified Analysis
Stroke is a severe disease that causes disability in many patients, warranting the urgent development of treatment options.1-4 Previous studies have reported that the risk of hemorrhagic stroke (HS) linearly increases with increasing alcohol intake.5-12 Furthermore, moderate alcohol intake has been shown to lower the risk of ischemic stroke (IS), and a J-curve association has been observed between alcohol consumption and morbidity rate of IS.7-14 These reports were similar in that they considered alcohol intake as a risk factor for stroke development.
Source: Journal of Stroke and Cerebrovascular Diseases - April 26, 2022 Category: Neurology Authors: Hiroyuki Shiotsuki, Yasuaki Saijo, Yoichi Ogushi, Shotai Kobayashi Source Type: research

Screening for Fabry Disease in Japanese Patients with Young-Onset Stroke by Measuring α-Galactosidase A and Globotriaosylsphingosine
Fabry disease is an X-linked lysosomal storage disorder caused by mutations in GLA, which encodes the enzyme α-galactosidase A (α-Gal A). Although the prevalence of Fabry disease in patients with stroke has been reported to range from 0% to 4%, few cohort studies have examined Japanese stroke patients. We aimed to clarify the prevalence of Fabry disease and the frequency of GLA mutations among patients w ith young-onset stroke in Japan.
Source: Journal of Stroke and Cerebrovascular Diseases - September 7, 2018 Category: Neurology Authors: Naoto Kinoshita, Naohisa Hosomi, Hayato Matsushima, Masahiro Nakamori, Yoshiki Yagita, Takemori Yamawaki, Tsuyoshi Torii, Takeshi Kitamura, Yoshimasa Sueda, Ryo Shimomura, Mutsuko Araki, Tomohisa Nezu, Shiro Aoki, Satoshi Ishii, Hiroki Maruyama, Masayasu Source Type: research

Cost Effectiveness of Drive and Retrieve System in Hokkaido for Acute Ischemic Stroke Patient Treatment Using Geographic Information System
This study aims to simulate the cost effectiveness of the drive and retrieve system, which can be a method to enhance equality and cost effectiveness of treatments for acute ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - June 11, 2019 Category: Neurology Authors: Yasuhiro Morii, Toshiya Osanai, Tomoki Ishikawa, Kensuke Fujiwara, Takumi Tanikawa, Kiyohiro Houkin, Eiichi Kobayashi, Katsuhiko Ogasawara Source Type: research

Dabigatran for Japanese Patients with Atrial Fibrillation and Prior Stroke: A Subgroup Analysis of the J-Dabigatran Surveillance Program
Background: The study objective was to evaluate long-term safety and effectiveness of dabigatran 110 mg and 150 mg twice daily (bid) in patients with nonvalvular atrial fibrillation (NVAF) with a focus on secondary stroke prevention. Methods: In J-Dabigatran Surveillance, 6772 patients newly initiated on dabigatran to prevent ischemic stroke and systemic embolism were enrolled in Japan (1042 sites, December 2011 to November 2013). This subgroup analysis included patients with (1302) and without (5071) previous stroke/transient ischemic attack (TIA).
Source: Journal of Stroke and Cerebrovascular Diseases - February 25, 2020 Category: Neurology Authors: Masahiro Yasaka, Shinichiro Uchiyama, Hirotsugu Atarashi, Ken Okumura, Yukihiro Koretsune, Takeshi Yamashita, Atsushi Taniguchi, Taku Fukaya, Hiroshi Inoue, for the J-Dabigatran Surveillance Investigators Tags: Original article Source Type: research

A Nationwide Multi-Center Questionnaire Survey on the Real-World State and Issues Regarding Post-Stroke Complications in Japan
Post-stroke complications affect stroke survivors across the world, although data on them are limited. We conducted a questionnaire survey to examine the real-world state and issues regarding post-stroke complications in Japan, which represents a super-aged society.
Source: Journal of Stroke and Cerebrovascular Diseases - February 9, 2021 Category: Neurology Authors: Shuhei Ikeda, Kazuo Washida, Tomotaka Tanaka, Erika Kitajima, Tetsuya Chiba, Kazuki Fukuma, Takeshi Yoshimoto, Satoshi Saito, Yorito Hattori, Masafumi Ihara Source Type: research

Development of Machine Learning Models to Predict Probabilities and Types of Stroke at Prehospital Stage: the Japan Urgent Stroke Triage Score Using Machine Learning (JUST-ML)
AbstractIn conjunction with recent advancements in machine learning (ML), such technologies have been applied in various fields owing to their high predictive performance. We tried to develop prehospital stroke scale with ML. We conducted multi-center retrospective and prospective cohort study. The training cohort had eight centers in Japan from June 2015 to March 2018, and the test cohort had 13 centers from April 2019 to March 2020. We use the three different ML algorithms (logistic regression, random forests, XGBoost) to develop models. Main outcomes were large vessel occlusion (LVO), intracranial hemorrhage (ICH), suba...
Source: Translational Stroke Research - August 14, 2021 Category: Neurology Source Type: research

Association between Serum Uric Acid Level and Activity of Daily Living in Japanese Patients with Ischemic Stroke
An association between serum uric acid and outcomes of ischemic stroke has been reported, but the results are controversial. The aim of this study is to clarify how uric acid may affect activities of daily living after acute ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - July 6, 2017 Category: Neurology Authors: Shinya Kawase, Hisanori Kowa, Yutaka Suto, Hiroki Fukuda, Masayoshi Kusumi, Hiroyuki Nakayasu, Kenji Nakashima Source Type: research

Retrospective Analysis of Argatroban in 353 Patients with Acute Noncardioembolic Stroke
Argatroban is a thrombin inhibitor agent for acute noncardioembolic ischemic stroke in Japan. We studied the prognosis in patients with acute stroke treated by argatroban in comparison with the control group with ozagrel in our hospital.
Source: Journal of Stroke and Cerebrovascular Diseases - April 26, 2018 Category: Neurology Authors: Hiroaki Oguro, Shingo Mitaki, Hiroyuki Takayoshi, Satoshi Abe, Keiichi Onoda, Shuhei Yamaguchi Source Type: research

Impact of angiotensin-converting enzyme inhibition on platelet tissue factor expression in stroke-prone rats
Conclusion: The current study shows for the first time that in hypertension the number of TF-positive megakaryocytes increases thus releasing in the circulation more platelets carrying a functionally active TF. AngII stimulates platelets to express TF.
Source: Journal of Hypertension - May 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research