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Total 95915 results found since Jan 2013.

Designing potential siRNA molecules for silencing the gene of the nucleocapsid protein of Nipah virus: A computational investigation
Infect Genet Evol. 2022 May 27:105310. doi: 10.1016/j.meegid.2022.105310. Online ahead of print.ABSTRACTNipah virus (NiV), a zoonotic virus, engenders severe infections with noticeable complications and deaths in humans and animals. Since its emergence, it is frightening that this virus has been causing regular outbreaks in various countries, particularly Bangladesh, India, and Malaysia. Unfortunately, no efficient vaccine or drug is available to combat this baneful virus. It employs the nucleocapsid protein in its genetic material encapsidation, which is a crucial for viral replication. The small interfering RNAs (siRNAs)...
Source: Infection, Genetics and Evolution - May 31, 2022 Category: Genetics & Stem Cells Authors: A M U B Mahfuz Md Arif Khan Emran Hossain Sajib Anamika Deb Shafi Mahmud Mahmudul Hasan Otun Saha Ariful Islam M Mizanur Rahaman Source Type: research

Masks versus prongs as interfaces for nasal continuous positive airway pressure in preterm infants
CONCLUSIONS: The available trial data provide low-certainty evidence that use of masks compared with prongs as the nasal CPAP interface may reduce treatment failure and nasal injury, and may have little or no effect on mortality or the risk of pneumothorax in newborn preterm infants with or at risk of respiratory distress. The effect on bronchopulmonary dysplasia is very uncertain. Large, high-quality trials would be needed to provide evidence of sufficient validity and applicability to inform policy and practice.PMID:36374241 | PMC:PMC9662142 | DOI:10.1002/14651858.CD015129
Source: Cochrane Database of Systematic Reviews - November 14, 2022 Category: General Medicine Authors: Raj Prakash Antonio G De Paoli Sam J Oddie Peter G Davis William McGuire Source Type: research

Yoga for chronic non-specific low back pain
CONCLUSIONS: There is low- to moderate-certainty evidence that yoga compared to no exercise results in small and clinically unimportant improvements in back-related function and pain. There is probably little or no difference between yoga and other back-related exercise for back-related function at three months, although it remains uncertain whether there is any difference between yoga and other exercise for pain and quality of life. Yoga is associated with more adverse events than no exercise, but may have the same risk of adverse events as other exercise. In light of these results, decisions to use yoga instead of no exe...
Source: Cochrane Database of Systematic Reviews - November 18, 2022 Category: General Medicine Authors: L Susan Wieland Nicole Skoetz Karen Pilkington Shireen Harbin Ramaprabhu Vempati Brian M Berman Source Type: research

Australian Authorities Regret the ‘Unacceptable’ End to MH370 Search
(SYDNEY) – Australian authorities said they deeply regret not finding missing Malaysia Airlines Flight MH370 and the ongoing mystery is “unacceptable,” in their final report on the unsuccessful search which was published on Tuesday. “The reasons for the loss of MH370 cannot be established with certainty until the aircraft is found,” the Australian Transport Safety Bureau (ATSB) said in the report. “It is almost inconceivable and certainly societally unacceptable in the modern aviation era… for a large commercial aircraft to be missing and for the world not to know with certainty wh...
Source: TIME.com: Top Science and Health Stories - October 3, 2017 Category: Consumer Health News Authors: Reuters Tags: Uncategorized Aviation MH370 onetime World Source Type: news

How Search Engine Data Enhance the Understanding of Determinants of Suicide in India and Inform Prevention: Observational Study
Conclusions: In this work, we used search data and demographics to model suicide rates. In this way, search data serve as a proxy for unmeasured (hidden) factors corresponding to suicide rates. Moreover, our procedure for outlier rejection serves to single out states where the suicide rates have substantially different correlations with demographic factors and query rates.
Source: Journal of Medical Internet Research - January 4, 2019 Category: General Medicine Authors: Natalia Adler Ciro Cattuto Kyriaki Kalimeri Daniela Paolotti Michele Tizzoni Stefaan Verhulst Elad Yom-Tov Andrew Young Source Type: research

Celebrity drug use reporting in Indian media and its impact on drug-related online search behavior: An infodemiology study
CONCLUSION: Media discussions on celebrity drug use may impact the online search behavior of the general public adversely. There is an need to develop and adhere to drug use reporting guidelines by media professionals.PMID:34456353 | PMC:PMC8363902 | DOI:10.4103/indianjpsychiatry.indianjpsychiatry_1329_20
Source: Indian Journal of Psychiatry - August 30, 2021 Category: Psychiatry Authors: Swarndeep Singh Gayatri Bhatia Pawan Sharma Arpit Parmar Source Type: research