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Factors associated with depressive mood at the onset of multiple sclerosis - an analysis of 781 patients of the German NationMS cohort
CONCLUSION: Depressive symptoms need to be assessed in early MS. Patients during relapse seem especially vulnerable to depressive symptoms. Contributing factors such as fatigue, vitamin D deficiency and smoking, could specifically be targeted in future interventions and should be investigated in prospective studies.PMID:37692259 | PMC:PMC10492471 | DOI:10.1177/17562864231197309
Source: Adv Data - September 11, 2023 Category: Epidemiology Authors: Anke Salmen Robert Hoepner Vinzenz Fleischer Milena Heldt Barbara Gisevius Jeremias Motte Klemens Ruprecht Ruth Schneider Anna Lena Fisse Thomas Gr üter Carsten Lukas Achim Berthele Katrin Giglhuber Martina Flaskamp Mark M ühlau Jan Kirschke Stefan Bitt Source Type: research

Consensus recommendations on regional interdisciplinary standardization of MRI diagnostics for multiple sclerosis in the metropolitan area of Essen
Nervenarzt. 2023 Aug 18. doi: 10.1007/s00115-023-01531-2. Online ahead of print.ABSTRACTMagnetic resonance imaging (MRI) is of exceptional importance in the diagnostics and monitoring of multiple sclerosis (MS); however, a close interdisciplinary cooperation between neurologists in private practice, (neuro)radiological practices, hospitals or specialized MS centers is only rarely established. In particular, there is a lack of standardized MRI protocols for image acquisition as well as established quality parameters, which guarantee the comparability of MRI records; however, this is a fundamental prerequisite for an effecti...
Source: Der Nervenarzt - August 18, 2023 Category: Neurology Authors: Mark Stettner Mike P Wattjes Karlgeorg Kr üger Refik Pul Michael Fleischer Ute Achnitz Heike Agne Kathlen Bach Ralf Berkenfeld Ulrike Bongartz Anja Br üggemann Lars Burgsm üller Joseph Cohnen Cornelius Deuschl Anke Friedrich Patrizia Graziano Jana Hack Source Type: research

Assessment of hepatic function employing hepatocyte specific contrast agent concentrations to multifactorially evaluate fibrotic remodeling
CONCLUSIONS: T1 mapping-based quantification of hepatic Gd-EOB-DTPA concentrations performed in a multiparametric model shows promising diagnostic accuracy for the detection of fibrotic changes. Liver biopsy might be replaced by imaging examinations.PMID:37456296 | PMC:PMC10347321 | DOI:10.21037/qims-22-884
Source: Molecular Medicine - July 17, 2023 Category: Molecular Biology Authors: Hanns-Christian Breit Jan Vosshenrich Tobias Heye Julian Gehweiler David Jean Winkel Silke Potthast Elmar Max Merkle Daniel Tobias Boll Source Type: research

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