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Vaccination: Cancer Vaccines
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Total 176 results found since Jan 2013.
Nationwide Prevalence and Genotype Distribution of High-Risk Human Papillomavirus Infection in China
CONCLUSIONS: Nationwide hrHPV genotyping results from KingMed laboratories offer a baseline for measuring the future impact of large-scale HPV vaccination. High hrHPV infection rates in older (≥50 years) Chinese women likely reflect the limited extent of cervical screening in China. High rates of hrHPV infection and variable regional hrHPV genotype distribution may represent limiting factors for cost-effective implementation of hrHPV-based cervical screening in China.PMID:34724029 | DOI:10.1093/ajcp/aqab181
Source: American Journal of Clinical Pathology - November 1, 2021 Category: Pathology Authors: Zhengyu Zeng R Marshall Austin Lin Wang Xiaolei Guo Qiuqiong Zeng Baowen Zheng Chengquan Zhao Source Type: research
Genetic characteristics of human papillomavirus type 16, 18, 52 and 58 in southern China
Genomics. 2021 Sep 20:S0888-7543(21)00348-7. doi: 10.1016/j.ygeno.2021.09.006. Online ahead of print.ABSTRACTPersistent infections of high-risk human papillomaviruses (HPVs) are the leading cause of cervical cancers. We collected cervical exfoliated cell samples from females in Changsha city, Hunan Province and obtained 358 viral genomes of four major HPV types, including HPV 16 (n = 82), 18 (n = 35), 52 (n = 121) and 58 (n = 100). The lineage/sublineage distribution of the four HPVs confirmed previous epidemiological reports, with the predominant prevailing sublineage as A4 (50%), A1 (37%) and A3 (13%) for HPV16, A1 (83%)...
Source: Genomics - September 23, 2021 Category: Genetics & Stem Cells Authors: Yuee Zu Zhihua Ou Dan Wu Wei Liu Liwen Liu Di Wu Yanping Zhao Peidi Ren Yanqing Zhang Wangsheng Li Shujin Fu Yongchun Wen Xianchu Cai Wenbo Liao Chunyu Geng Hongcheng Zhou Xiaman Wang Haorong Lu Huanhuan Peng Na Liu Shida Zhu Jiyang Liu Dongbo Wang Junhua Source Type: research
Quercetin as an antiviral agent inhibits the Pseudorabies virus in vitro and in vivo
This study involved quercetin for studying the anti-PRV function in vitro and in vivo. Quercetin was found to significantly decrease the PRV virulent strain HNX at a half-maximal inhibitory concentration (IC50) of 2.618 μM and selectivity index 229. This anti-PRV activity of quercetin was found to be dose-dependent. Furthermore, quercetin also inhibited a wide the infections by a spectrum of PRV strains like HNX, Ea, Bartha and Fa strain. These virucidal effects of quercetin suggest the interaction between these molecules and viral particles, and quercetin is responsible for inhibiting the adsorption of PRV infections. Th...
Source: Virus Research - September 7, 2021 Category: Virology Authors: Yumei Sun Chang Li Zhonghua Li Aishao Shangguan Jinhe Jiang Wei Zeng Shujun Zhang Qigai He Source Type: research
