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Specialty: Cardiology
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Total 500 results found since Jan 2013.

Red Meat Consumption and Risk of Cardio-Cerebrovascular Disease in Chinese Older Adults
Int Heart J. 2023;64(4):654-662. doi: 10.1536/ihj.23-138.ABSTRACTAssociations between red meat consumption and cardio-cerebrovascular diseases (CCVDs) are mostly studied in Western populations but not in Chinese or elderly. This prospective study investigated adults ≥65 years from the China Kadoorie Biobank (CKB). Associations between red meat consumption and CCVD, ischemic stroke/transient ischemic attack (TIA), CCVD mortality, and all-cause mortality were determined by Cox regression. A total of 59,980 participants were analyzed, 14,715 (24.53%) of whom ate red meat daily, 9,843 (16.41%) ate red meat 4-6 days/week, 23,...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Xiaojia Sun Ruihong Sun Liming Zhang Source Type: research

Based on network pharmacology and molecular docking to predict the mechanism of TMDZ capsule in the treatment of IS
CONCLUSIONS: This study reveals the molecular mechanism of TMDZ capsules in the treatment of IS by integrating molecular docking with a network pharmacological strategy, which not only confirmed the clinical efficacy of TMDZ capsule, but also laid the foundation for further experimental research.PMID:37505183 | DOI:10.1097/MD.0000000000034424
Source: Atherosclerosis - July 28, 2023 Category: Cardiology Authors: Fengjiao Yang Yun Gu Ya Yan Guangming Wang Source Type: research

Statins influence the relationship between ATP-binding cassette A1 membrane transporter-mediated cholesterol efflux capacity and coronary atherosclerosis in rheumatoid arthritis
CONCLUSION: In patients with RA, higher ABCA1-CEC may reflect a proatherogenic state, associated with enhanced cardiovascular risk. Statin use may unmask the protective impact of ABCA1-mediated cholesterol efflux on plaque formation, progression and cardiovascular risk.PMID:37484708 | PMC:PMC10362327 | DOI:10.1016/j.jtauto.2023.100206
Source: Atherosclerosis - July 24, 2023 Category: Cardiology Authors: George A Karpouzas Bianca Papotti Sarah R Ormseth Marcella Palumbo Elizabeth Hernandez Maria Pia Adorni Francesca Zimetti Matthew J Budoff Nicoletta Ronda Source Type: research

The value of serum Lp-PLA2 combined with MPO in the diagnosis of cerebral infarction caused by large artery atherosclerosis
CONCLUSION: Serum Lp-PLA2 combined with MPO could be valued as a predictor of acute cerebral infarction caused by large artery atherosclerosis.PMID:37467579 | DOI:10.1016/j.clineuro.2023.107899
Source: Atherosclerosis - July 19, 2023 Category: Cardiology Authors: Min Hua Wen-Ya Chen Li-Hui Wang Xiao-Hua Zou Lun-Lin Mao Source Type: research

Dengyinnaotong attenuates atherosclerotic lesions, gut dysbiosis and intestinal epithelial barrier impairment in the high fat diet-fed ApoE < sup > -/- < /sup > mice
CONCLUSIONS: Our work provides novel preclinical evidence that underpins the multifaceted effects of DYNT in the control of atherosclerosis.PMID:37453620 | DOI:10.1016/j.jep.2023.116916
Source: Atherosclerosis - July 15, 2023 Category: Cardiology Authors: Minqi Xiong Zilong Zhang Jingang Cui Xiaoye Du Yu Chen Teng Zhang Source Type: research

Association between remnant cholesterol and subclinical carotid atherosclerosis among Chinese general population in health examination
CONCLUSION: Elevated serum RC levels were significantly associated with CAS and increased CIMT among Chinese general population, independent of LDL-C and HDL-C. RC evaluation could be applied for the risk management of early stage of subclinical carotid atherosclerosis in health examination.PMID:37392486 | DOI:10.1016/j.jstrokecerebrovasdis.2023.107234
Source: Atherosclerosis - July 1, 2023 Category: Cardiology Authors: Nimei Zeng Yu'e Shen Yuan Li Yun Wang Source Type: research

Epigenome-wide association study identifies novel genes associated with ischemic stroke
CONCLUSIONS: Altered DNA methylation of the TRIM6, TLN2, and FLRT2 genes may play a functional role in ischemic stroke in Chinese populations.PMID:37370144 | DOI:10.1186/s13148-023-01520-x
Source: Atherosclerosis - June 27, 2023 Category: Cardiology Authors: Hao Peng Helena Palma-Gudiel Carolina Soriano-Tarraga Jordi Jimenez-Conde Mingzhi Zhang Yonghong Zhang Jinying Zhao Source Type: research

Neuroprotective effect of Astragali Radix on cerebral infarction based on proteomics
Conclusion: This study found that AR can significantly recover the clinical symptoms of CI. Serum proteomics research results show that AR may act on IL-6, TNF-α, VCAM-1, MCP-1, and ICAM-1, and play anti-atherosclerosis and neuroprotective roles. Clinical Trial Registration: [clinicaltrials.gov], identifier [NCT02846207].PMID:37361203 | PMC:PMC10289882 | DOI:10.3389/fphar.2023.1162134
Source: Atherosclerosis - June 26, 2023 Category: Cardiology Authors: Ying Li Daoping Wang Rongjuan Guo Bo Ma Lan Miao Mingqian Sun Lijuan He Li Lin Yinghong Pan Junguo Ren Jianxun Liu Source Type: research

Association of Homocysteine with Acute Stroke and Its Subtypes in the Chinese Population
CONCLUSION: Plasma Hcy levels were found to be positively correlated with the risk of stroke, particularly in the context of LAA, SAO stroke, and HICH. Additionally, Hcy levels demonstrated a positive correlation with stroke severity in patients presenting with SAO stroke. These findings suggest potential clinical implications in stroke prevention, particularly for ischemic stroke (LAA, SAO subtypes) and HICH by employing homocysteine-lowering therapies. Future investigations are warranted to fully elucidate these associations.PMID:37342757 | PMC:PMC10278861 | DOI:10.2147/NDT.S409591
Source: Atherosclerosis - June 21, 2023 Category: Cardiology Authors: Panpan Zhang Yurong Zhang Source Type: research

Determinants of self-rated health among elderly patients with hypertension: a cross-sectional analysis based on the Chinese longitudinal healthy longevity survey
CONCLUSION: The findings of this study provide evidence for the need to develop effective health promotion programs for the well-being of hypertensive patients.PMID:37337961 | DOI:10.1080/10641963.2023.2224942
Source: Clinical and Experimental Hypertension - June 20, 2023 Category: Cardiology Authors: Yang Zhou Yanjing Huang Aohua Zhang Guige Yin Hongjuan Hu Source Type: research