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Flow, Reflected by Stroke Volume Index, is a Risk Marker in High Gradient Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Replacement
ConclusionsSVi can further characterise patients with HG-AS and may help to identify those who are at increased risk following TAVR.
Source: Canadian Journal of Cardiology - August 30, 2019 Category: Cardiology Source Type: research

Flow, Reflected by Stroke Volume Index, Is a Risk Marker in High-Gradient Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Replacement
ConclusionsSVi can further characterize patients with HG-AS and may help to identify those who are at increased risk after TAVR.RésuméContexteDes outils sont nécessaires pour dépister les patients exposés à un risque accru à la suite d’un remplacement valvulaire aortique par cathéter (RVAC). Le volume systolique indexé (VSI) est une mesure échocardiographique utilisée dans les cas de sténose aortique à faible gradient. Nous avons vérifié si un faible VSI était un marqueur de risque accru chez les patients présentant une sténose aortique à gradient élevé et avons évalué comment la relation entre le ...
Source: Canadian Journal of Cardiology - December 24, 2019 Category: Cardiology Source Type: research

Sex-Related Differences in Patients Undergoing Thoracic Aortic Surgery: Evidence from the Canadian Thoracic Aortic Collaborative.
CONCLUSIONS: Women experience worse outcomes following thoracic aortic surgery with hypothermic circulatory arrest. Further investigation is required to better delineate which measures may reduce sex-related outcome differences following complex aortic surgery. PMID: 30755026 [PubMed - as supplied by publisher]
Source: Circulation - February 13, 2019 Category: Cardiology Authors: Chung J, Stevens LM, Ouzounian M, El-Hamamsy I, Bouhout I, Dagenais F, Cartier A, Peterson M, Boodhwani M, Guo MH, Bozinovski J, Yamashita MH, Lodewyks C, Atoui R, Bittira B, Payne D, Tarola C, Chu MWA, Canadian Thoracic Aortic Collaborative Tags: Circulation Source Type: research

Sex-specific differences in outcome of transcatheter or surgical aortic valve replacement
Conclusions This nation-wide analysis of sex-specific outcomes after aortic-valve replacement procedures showed that women are higher-risk for bleeding, but lower-risk for stroke, mechanical ventilation, and TF-TAVR mortality. Understanding these differences and their basis may help improve outcomes. Teaser We analyzed baseline characteristics and outcomes of all isolated TAVR or SAVR procedures performed in Germany between 2011 and 2014. In comparison to male patients, females were preferentially treated with TF-TAVR rather than SAVR due to their generally older age and higher EuroSCORE. Females suffered from more relevan...
Source: Canadian Journal of Cardiology - April 13, 2018 Category: Cardiology Source Type: research

Antithrombotic Management After Transcatheter Aortic Valve Replacement: A Survey of Canadian Physicians
Publication date: November 2019Source: Canadian Journal of Cardiology, Volume 35, Issue 11Author(s): Seleman Reza, Natalia Pinilla, Emilie P. Belley-Côté, Kevin J. Um, Serena Sibilio, Madhu K. Natarajan, Richard P. WhitlockAbstractOptimal postprocedural antithrombotic regimen is uncertain after transcatheter aortic valve replacement (TAVR). We developed an online questionnaire on post-TAVR antithrombotic management. After research ethics board approval, we distributed the survey to TAVR implanters across Canada. A total of 24 TAVR implanters from 17 centres responded to the survey for a response rate of 75%. Dual antipla...
Source: Canadian Journal of Cardiology - November 2, 2019 Category: Cardiology Source Type: research

Sex-Specific Differences in Outcome of Transcatheter or Surgical Aortic Valve Replacement
ConclusionsThis nation-wide analysis of sex-specific outcomes after aortic-valve replacement procedures showed that women are higher-risk for bleeding, but lower-risk for stroke, mechanical ventilation, and TF-TAVR mortality. Understanding these differences and their basis may help improve outcomes.RésuméContexteLes différences anatomiques et celles au niveau des caractéristiques initiales entre patients de sexe masculin et féminin présentant une sténose valvulaire aortique pourraient influencer l’issue après un remplacement valvulaire aortique par voie chirurgicale et transcathéter. Nous avons évalué l’effe...
Source: Canadian Journal of Cardiology - July 24, 2018 Category: Cardiology Source Type: research

Transcatheter vs Surgical Aortic Valve Replacement for Aortic Stenosis in Low-Intermediate Risk Patients: A Meta-analysis
Conclusions Although there was no difference in 30-day and late mortality, the rate of complications differed between TAVR and SAVR in the low-intermediate surgical risk population.
Source: Canadian Journal of Cardiology - August 25, 2017 Category: Cardiology Source Type: research

Impact of Discharge Location After Transcatheter Aortic Valve Replacement On 1-Year Outcomes In Women: Results From The WIN-TAVI Registry
ConclusionsIn women undergoing contemporary TAVR, discharge disposition significantly affects 1-year risk of outcomes even after adjustment for recorded baseline differences. This might suggest the necessity of considering additional factors beyond comorbidities in the TAVR decision-making process.
Source: Canadian Journal of Cardiology - December 12, 2018 Category: Cardiology Source Type: research

Aortic root enlargement is safe and reduces the incidence of patient-prosthesis mismatch: A Meta-analysis of early and late outcomes
ConclusionsSurgical ARE is a safe adjunct to AVR in selected patients that does not increase early adverse events and results in less patient-prosthesis mismatch. This strategy allows for a larger valve size at the time of implantation – an important consideration for potential future valve-in-valve procedures in the era of TAVR.
Source: Canadian Journal of Cardiology - February 13, 2019 Category: Cardiology Source Type: research

Outcome Of Patients Undergoing Transcatheter Implantation Of Aortic Valve With Previous Mitral Valve Prosthesis (OPTIMAL STUDY)
ConclusionsTAVR in patients with a previous mitral prosthesis appears safe and feasible, with good hemodynamic results at 30-day and at longer term follow-up.
Source: Canadian Journal of Cardiology - April 16, 2019 Category: Cardiology Source Type: research

Arrhythmias in Adults with Congenital Heart Disease: What the Practicing Cardiologist Needs to Know
Publication date: Available online 16 July 2019Source: Canadian Journal of CardiologyAuthor(s): Paul KhairyAbstractThe expanding population of adults with congenital heart disease (CHD) combined with the pervasiveness of arrhythmias has resulted in the rapid growth of a dedicated sector of cardiology at the intersection between two subspecialties: electrophysiology and adult CHD. Herein, practical considerations are offered regarding urgent referral for catheter ablation of atrial arrhythmias, anticoagulation, and primary prevention implantable cardioverter-defibrillators (ICDs). Patients with Ebstein anomaly and ventricul...
Source: Canadian Journal of Cardiology - July 17, 2019 Category: Cardiology Source Type: research

Antithrombotic Management Following Transcatheter Aortic Valve Replacement: A Survey of Canadian Physicians
Publication date: Available online 22 August 2019Source: Canadian Journal of CardiologyAuthor(s): Seleman Reza Bsc, Natalia Pinilla, Emilie P. Belley-Côté, Kevin J. Um, Serena Sibilio, Madhu K. Natarajan, Richard P. WhitlockAbstractOptimal post-procedural antithrombotic regimen is uncertain after transcatheter aortic valve replacement (TAVR). We developed an online questionnaire on post-TAVR antithrombotic management. After research ethics board approval, we distributed the survey to TAVR implanters across Canada. A total of 24 TAVR implanters from 17 centres responded to the survey for a response rate of 75%. Dual antip...
Source: Canadian Journal of Cardiology - August 22, 2019 Category: Cardiology Source Type: research

Comparison of a Complete Percutaneous versus Surgical Approach to Aortic Valve Replacement and Revascularization in Patients at Intermediate Surgical Risk: Results from the Randomized SURTAVI Trial.
CONCLUSIONS: For patients at intermediate surgical risk with severe AS and non-complex CAD (SYNTAX score ≤ 22), a complete percutaneous approach of TAVR and PCI is a reasonable alternative to SAVR and CABG. CLINICAL TRIAL REGISTRATION: URL: www.clinicaltrials.gov Unique Identifier: NCT01586910. PMID: 31476897 [PubMed - as supplied by publisher]
Source: Circulation - September 2, 2019 Category: Cardiology Authors: Søndergaard L, Popma JJ, Reardon MJ, Van Mieghem NM, Deeb GM, Kodali S, George I, Williams MR, Yakubov SJ, Kappetein AP, Serruys PW, Grube E, Schiltgen MB, Chang Y, Engstrøm T, SURTAVI Trial Investigators Tags: Circulation Source Type: research

Predictors of Cumulative Health Care Costs Associated with Transcatheter Aortic Valve Replacement in Severe Aortic Stenosis
ConclusionsThis analysis shows that there are 3 distinct phases of cost accumulation from referral to post-TAVR with some potentially modifiable cost drivers in each phase.
Source: Canadian Journal of Cardiology - December 18, 2019 Category: Cardiology Source Type: research