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Total 432 results found since Jan 2013.
UDP-Glucose Ceramide Glycosyltransferase Contributes to the Proliferation and Glycolysis of Cervical Cancer Cells by Regulating the PI3K/AKT Pathway
CONCLUSION: The knockdown of UGCG exerted an anti-tumor effect against cervical cancer through the inactivation of the PI3K/AKT pathway.PMID:34686508
Source: Annals of Clinical and Laboratory Science - October 23, 2021 Category: Laboratory Medicine Authors: Fenyun Zhang Hao Zhang Source Type: research
Phactr1 negatively regulates bone mass by inhibiting osteogenesis and promoting adipogenesis of BMSCs via RhoA/ROCK2
AbstractThe imbalance between osteogenic and adipogenic differentiation of Bone marrow-derived mesenchymal stem cells (BMSCs) is involved in the occurrence and development of osteoporosis (OP). Previous studies have indicated the potential of phosphatase and actin regulator 1 (Phactr1) in regulating osteogenic and adipogenic differentiation of BMSCs. The present study aims to investigate the function and mechanism of Phactr1 in regulating osteogenic and adipogenic differentiation of BMSCs. Herein, the expression of Phactr1 in bone and adipose tissue of OP rats was determined by immunohistochemical. BMSCs were subjected to ...
Source: Journal of Molecular Histology - October 28, 2021 Category: Laboratory Medicine Source Type: research
UDP-Glucose Ceramide Glycosyltransferase Contributes to the Proliferation and Glycolysis of Cervical Cancer Cells by Regulating the PI3K/AKT Pathway
CONCLUSION: The knockdown of UGCG exerted an anti-tumor effect against cervical cancer through the inactivation of the PI3K/AKT pathway.PMID:34686508
Source: Annals of Clinical and Laboratory Science - October 23, 2021 Category: Laboratory Medicine Authors: Fenyun Zhang Hao Zhang Source Type: research
Identification and Validation of a Proliferation-Associated Score Model Predicting Survival in Lung Adenocarcinomas
CONCLUSION: The proposed score model may function as a promising risk prediction tool for patients with lung adenocarcinoma and provide insights into the molecular regulation mechanism of lung adenocarcinoma.PMID:34721732 | PMC:PMC8554523 | DOI:10.1155/2021/3219594
Source: Disease Markers - November 1, 2021 Category: Laboratory Medicine Authors: Yunyi Bian Qihai Sui Guoshu Bi Yuansheng Zheng Mengnan Zhao Guangyu Yao Liang Xue Yi Zhang Hong Fan Source Type: research
UDP-Glucose Ceramide Glycosyltransferase Contributes to the Proliferation and Glycolysis of Cervical Cancer Cells by Regulating the PI3K/AKT Pathway
CONCLUSION: The knockdown of UGCG exerted an anti-tumor effect against cervical cancer through the inactivation of the PI3K/AKT pathway.PMID:34686508
Source: Annals of Clinical and Laboratory Science - October 23, 2021 Category: Laboratory Medicine Authors: Fenyun Zhang Hao Zhang Source Type: research
Identification and Validation of a Proliferation-Associated Score Model Predicting Survival in Lung Adenocarcinomas
CONCLUSION: The proposed score model may function as a promising risk prediction tool for patients with lung adenocarcinoma and provide insights into the molecular regulation mechanism of lung adenocarcinoma.PMID:34721732 | PMC:PMC8554523 | DOI:10.1155/2021/3219594
Source: Disease Markers - November 1, 2021 Category: Laboratory Medicine Authors: Yunyi Bian Qihai Sui Guoshu Bi Yuansheng Zheng Mengnan Zhao Guangyu Yao Liang Xue Yi Zhang Hong Fan Source Type: research
UDP-Glucose Ceramide Glycosyltransferase Contributes to the Proliferation and Glycolysis of Cervical Cancer Cells by Regulating the PI3K/AKT Pathway
CONCLUSION: The knockdown of UGCG exerted an anti-tumor effect against cervical cancer through the inactivation of the PI3K/AKT pathway.PMID:34686508
Source: Annals of Clinical and Laboratory Science - October 23, 2021 Category: Laboratory Medicine Authors: Fenyun Zhang Hao Zhang Source Type: research
