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Total 203 results found since Jan 2013.

Amino Acid Profile in 18 Patients with Rheumatic Diseases Treated with Glucocorticoids and BCAAs
J Nutr Sci Vitaminol (Tokyo). 2021;67(3):180-188. doi: 10.3177/jnsv.67.180.ABSTRACTThe administration of glucocorticoids to patients with rheumatic diseases often results in glucocorticoid-induced myopathy. We previously found that administration of branched-chain amino acids (BCAA) to such patients improves the loss of skeletal muscle, however, their individual differences were often observed. The present study, therefore, aims to identify specific parameters associated with BCAA-induced increases in skeletal muscle mass. Eighteen patients with rheumatic diseases treated with prednisolone were randomly assigned to receive...
Source: Journal of Nutritional Science and Vitaminology - July 1, 2021 Category: Nutrition Authors: Noritada Yoshikawa Motohisa Yamamoto Akiko Kuribara-Souta Masaaki Uehara Hiroki Yamazaki Hirotoshi Tanaka Source Type: research

Case Report: Mitochondrial Encephalomyopathy Presents as Epilepsy, Ataxia, and Dystonia With a Rare Mutation in MT-TW
Mitochondrial diseases are a group of common inherited disorders caused by mutations in nuclear DNA or mitochondrial DNA (mtDNA); the clinical phenotype of diseases caused by mutant mtDNA is challenging owing to heteroplasmy of mtDNA and may delay diagnosis and treatment. Herein, we report the case of an adult male who slowly developed epilepsy, ataxia, dystonia, impaired cognition, and hearing impairment over 14 years in the absence of clinical myopathy. His lactate level was normal. Brain computed tomography showed calcifications of the bilateral basal ganglia, thalamus, and cerebellar dentate nuclei. Magnetic resonance ...
Source: Frontiers in Neurology - July 1, 2021 Category: Neurology Source Type: research

A Case of Pathological Complete Response and Resolution of Dermatomyositis Following Neoadjuvant Chemotherapy in HER2-Positive Early Breast Cancer
Discussion and conclusion. Similar cases in literature are commonly referred to a first-line surgery and the role of neoadjuvant chemotherapy is debatable.PMID:34073827 | PMC:PMC8161769 | DOI:10.3390/curroncol28030182
Source: Current Oncology - June 2, 2021 Category: Cancer & Oncology Authors: Marta Piras Martina Panebianco Matteo Garibaldi Michela Roberto Gioia Merlonghi Patrizia Pellegrini Paolo Marchetti Source Type: research