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Top 20 Research Studies of 2020 for Primary Care Physicians
This article summarizes the top 20 research studies of 2020 identified as POEMs (patient-oriented evidence that matters), including the two most highly rated guidelines of the year on gout and chronic obstructive pulmonary disease (COPD). Regarding COVID-19, handwashing and social distancing through stay-at-home orders or quarantine measures are effective at slowing the spread of illness. Use of proper face masks (not gaiters or bandanas) is also effective at preventing trans- mission. This is important because the virus can infect others during the presymptomatic phase. Aspirin can no longer be recommended for the primary...
Source: Pain Physician - July 15, 2021 Category: Anesthesiology Authors: Roland Grad Mark H Ebell Source Type: research
What to Know About a Fourth COVID-19 Vaccine Dose
Most people ages 12 and older are considered “up to date” with their COVID-19 vaccines if they received either three doses of the mRNA shots from Pfizer-BioNTech or Moderna, or two doses of Johnson & Johnson’s Janssen vaccine. But some public health experts say another dose might be needed in the coming months.
The Washington Post reports today that Pfizer and BioNTech soon plan to request authorization from the U.S. Food and Drug Administration (FDA) for a fourth dose of their vaccine in people ages 65 and older. In the past few days, Albert Bourla, Pfizer’s CEO, has said that he believes every...
Source: TIME: Health - March 15, 2022 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news
Vaccines against SARS ‐CoV‐2 are safe to administer in patients with antibodies to pegaspargase
ConclusionSARS-CoV-2 vaccination is safe in this population.
Source: Cancer Medicine - July 15, 2022 Category: Cancer & Oncology Authors: Hope D. Swanson,
Hana Hakim,
Diego R. Hijano,
Ted Morton,
Shane Cross,
Hiroto Inaba,
Sima Jeha,
Ching ‐Hon Pui,
Seth E. Karol Tags: BRIEF COMMUNICATION Source Type: research
Finding On Killer Cells Opens New Avenue For Combating AIDS, Cancer And Other Diseases
A research team led by the La Jolla Institute for Allergy & Immunology has discovered the mechanism that enables CD4 helper T cells to assume the more aggressive role of killer T cells in mounting an immune attack against viruses, cancerous tumors and other damaged or infected cells. The finding, made in collaboration with researchers from the RIKEN Institute in Japan, could enable the development of more potent drugs for AIDS, cancer and many other diseases based on using this mechanism to trigger larger armies of killer T cells against infected or damaged cells...
Source: Health News from Medical News Today - January 22, 2013 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news
La Jolla Institute Identifies Molecular SwitchEnabling Immune Cells To Better Fight Disease
Finding on Killer Cells Opens New Avenue for Combating AIDS, Cancer and other Diseases A research team led by the La Jolla Institute for Allergy & Immunology has discovered the mechanism that enables CD4 helper T cells to assume the more aggressive role of killer T cells in mounting an immune attack against viruses, cancerous tumors and other damaged or infected cells...
Source: Health News from Medical News Today - January 24, 2013 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news
RNA: The new revolution in nucleic acid vaccines.
Abstract
Nucleic acid vaccines have the potential to address issues of safety and effectiveness sometimes associated with vaccines based on live attenuated viruses and recombinant viral vectors. In addition, methods to manufacture nucleic acid vaccines are suitable as generic platforms and for rapid response, both of which will be very important for addressing newly emerging pathogens in a timely fashion. Plasmid DNA is the more widely studied form of nucleic acid vaccine and proof of principle in humans has been demonstrated, although no licensed human products have yet emerged. The RNA vaccine approach, based on...
Source: Seminars in Immunology - June 1, 2013 Category: Allergy & Immunology Authors: Geall AJ, Mandl CW, Ulmer JB Tags: Semin Immunol Source Type: research
New HIV vaccine hope?
Conclusion
This fascinating research has looked into the effects of a vaccine against the monkey equivalent of the HIV virus (called SIV). The vaccine previously showed the ability to protect about half of the monkeys vaccinated against infection, and the current study wanted to investigate this effect further. The results suggest that the vaccine can protect the monkeys against SIV infection from various routes. They also suggest that in monkeys that show vaccine protection after an initial period where the virus lingers, they eventually seem able to clear the infection from their body.
The authors cautiously note that...
Source: NHS News Feed - September 13, 2013 Category: Consumer Health News Tags: Medication Source Type: news
Measles numbers multiply, myths linger
Measles. Many adults associate it with mild illness and relatively harmless red spots. Not quite, says Ronald Samuels, MD, MPH, associate medical director of Boston Children’s Primary Care Center. “Measles is different from chicken pox. A mild case of measles doesn’t exist.” That message takes on a new urgency in light of data released by the Centers for Diseases Control and Prevention (CDC), which tallied 159 reported cases of measles from January 1-August 24 of this year.
The U.S. declared measles eliminated with no cases of continuous transmission for 12 months or longer in 2000. Since then, the number of annual...
Source: Thrive, Children's Hospital Boston - October 9, 2013 Category: Pediatrics Authors: Lisa Fratt Tags: All posts Diseases & conditions Vaccines measles MMR vaccination Source Type: news
