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Therapy: Immunotherapy

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Total 6127 results found since Jan 2013.

Home-Based Up-Dosing in Build-Up Phase of Oral Immunotherapy of Egg Allergy Is Safe and Feasible in Real-World Practice
Allergy Asthma Immunol Res. 2021 Sep;13(5):791-798. doi: 10.4168/aair.2021.13.5.791.ABSTRACTOral immunotherapy (OIT) has emerged to build sustained unresponsiveness or tolerance in patients with egg allergy. However, it is important to increase compliance and ensure safety because OIT requires an extended period of time and has a risk of side effects like anaphylaxis. We aimed to show the feasibility and safety of OIT during the build-up phase using a home-based, up-dosing method in children with egg allergy. Sixteen patients aged 4 to 12 years with egg allergy were enrolled. Patients increased the dose of boiled egg white...
Source: Allergy, Asthma and Immunology Research - September 6, 2021 Category: Allergy & Immunology Authors: Hye-In Jeong Bora Lee Sukyung Kim Yechan Kyung Minyoung Jung Minji Kim Ji Young Lee Kevin Kim Kangmo Ahn Jihyun Kim Source Type: research

Study protocol of a phase 2, dual-centre, randomised, controlled trial evaluating the effectiveness of probiotic and egg oral immunotherapy at inducing desensitisation or sustained unresponsiveness (remission) in participants with egg allergy compared with placebo (Probiotic Egg Allergen Oral Immunotherapy for Treatment of Egg Allergy: PEAT study)
This study has been approved by the Human Research Ethics Committees at the Royal Children’s Hospital (HREC 2019.082) and the National Healthcare Group Domain Specific Review Board (2019/00029). Results will be published in peer-reviewed journals and disseminated via presentations at international conferences. Trial registration number ACTRN12619000480189.
Source: BMJ Open - July 7, 2021 Category: General Medicine Authors: Loke, P., Chebar Lozinsky, A., Orsini, F., Wong, L. S.-Y., Leung, A. S.-Y., Tham, E. H., Lopata, A. L., Shek, L. P.-C., Tang, M. L., PEAT study team, Su, Robinson, Tey, Belousoff, Pitkin, Axelrad, Mitra, Chan, Yi, Ng Tags: Open access, Immunology (including allergy) Source Type: research

The Economic Burden of Food Allergy: What We Know and What We Need to Learn
AbstractPurpose of ReviewFood allergy management and treatment require dietary modification, are associated with significant burdens, and affect food choices and behaviours. Emerging therapies, such as oral immunotherapy (OIT), provide a glimmer of hope for those living with the condition. Some burdens have received substantial focus, whereas many knowledge gaps on the significance of other impacts, including economic burden, remain.Recent FindingsEvidence from many countries, but disproportionately from the United States, supports that food allergy carries significant healthcare and societal costs. Early introduction for ...
Source: Current Treatment Options in Allergy - April 28, 2022 Category: Allergy & Immunology Source Type: research

Anti-IgE for food allergy
CONCLUSIONS: Over the past 20 years, significant progress has been made in understanding the potential role of anti-IgE therapies for food allergy. Anti-IgE therapies appear to be a promising option that may increase reaction dose thresholds and decrease time to reach OIT maintenance and OIT dosing related reactions. Two Phase III trials are currently in progress studying anti-IgE potential monotherapy for the treatment of peanut and multi-food allergies. It is important for clinicians to be aware of these emerging treatment options.PMID:37031775 | DOI:10.1016/j.anai.2023.03.030
Source: Annals of Allergy, Asthma and Immunology - April 9, 2023 Category: Allergy & Immunology Authors: Jennifer A Dantzer Robert A Wood Source Type: research