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Metal Allergy Testing in Patients Listed for Temporomandibular Joint Replacement at Massachusetts General Hospital
Patients with temporomandibular joint (TMJ) arthropathies (i.e end-stage degeneration, invasive pathology, or developmental anomalies) may be candidates for total joint replacement (TJR). There is only one FDA-approved manufacturer of patient-specific alloplasts of the TMJ, Stryker-TMJ Concepts. Stryker can fabricate a custom prosthesis composed of a cobalt-chromium-molybdenum alloy, with a maximum of 1% nickel present in the condylar component. However, metal hypersensitivity can occur, which may cause failure in up to 3% of TMJ replacements.
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Hadley Johnson, Briana Burris, Joseph McCain, JiaDe Yu Source Type: research

Re: Prospective study of five-year outcomes and postoperative complications after total temporomandibular joint replacement with two stock prosthetic systems
Gonzalez-Perez et al state that an epicutaneous patch test for metal allergy ( “chrome cobalt molybdenum Co-Cr-Mb” – the correct chemical symbol for molybdenum is “Mo”), T.R.U.E. test® (SmartPractice Denmark ApS) was administered preoperatively.1 Presumably, but not stated clearly, this testing was administered to all patients before they had initial temporomandibul ar joint (TMJ) replacements using either the Christensen (CS), or the Biomet® systems (BS).
Source: The British Journal of Oral and Maxillofacial Surgery - March 4, 2020 Category: ENT & OMF Authors: L.G. Mercuri Tags: Letter to the Editor Source Type: research

Allergic reaction to Nickel and Titanium In patients with TMJ replacements: 2 case reports
Introduction Previous retropsective and prospective studies in the TMJ and orthopaedic literature have shown a high incidence (38-42%)12,3 of allergy to metals found in implant alloys in particular Nickel, Chrome and Cobalt. Incidence of metal allergy appears to be higher in patients who have had previous prostheses especially if a metal on metal prosthesis was used 3 Patch testing has been recommended in the UK before TMJ replacement and Titianium implants advised where allergy exists.
Source: The British Journal of Oral and Maxillofacial Surgery - November 30, 2019 Category: ENT & OMF Authors: Kapil Java, Martin Dodd Tags: P205 Source Type: research

Allergic reactions in oral and perioral diseases—what do allergy skin test results show?
ConclusionsAllergy skin tests are reliable and justified for diagnosing allergies in cases of persistent or recurrent oral diseases. This is the only way to confirm allergies and is the basis for consequent allergen avoidance for the benefit of the patient.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - September 16, 2018 Category: ENT & OMF Source Type: research

Allergic reactions in oral and perioral diseases - what do allergy skin test results show?
ConclusionAllergy skin tests are reliable and justified for diagnosing allergies in cases of persistent or recurrent oral diseases. This is the only way to confirm allergies and is the basis for consequent allergen avoidance for the benefit of the patient.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - August 18, 2018 Category: ENT & OMF Source Type: research

A prospective comparison study of 1 year outcomes for all-titanium versus cobalt–chromium total temporomandibular joint replacement in metal-allergic patients
Aim: To ascertain whether there are any early differences in outcome using all-Ti TMJ prostheses in metal allergic patients compared to standard cobalt-chromium prostheses in patients with no metal allergy.
Source: The British Journal of Oral and Maxillofacial Surgery - August 7, 2013 Category: ENT & OMF Authors: Omar Hussain, A.J. Sidebottom Tags: Abstracts Source Type: research