• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Eosinophilic inflammation of the digestive tract
Ann Pathol. 2023 May 10:S0242-6498(23)00091-3. doi: 10.1016/j.annpat.2023.04.007. Online ahead of print.ABSTRACTEosinophilic inflammation of the digestive tract is an inflammatory disease characterized by extensive infiltration of eosinophils into the gastrointestinal tract. It can be either a primary disorder of the digestive tract or be secondary to another cause of tissue eosinophilia. Primary disorders include eosinophilic esophagitis (OE) and eosinophilic gastroenteritis (GEEo). These are 2 rare pathologies considered to be diseases related to a Th2-mediated food allergy. The role of the pathologist is twofold: (1) he...
Source: Annales de Pathologie - May 12, 2023 Category: Pathology Authors: Nathalie Guedj Dominique Cazals-Hatem Source Type: research

A rare and unusual cause of mammographic calcification in the breast
Discussion Answer: C Histologically, there are focal collections of dilated ducts and microcysts lined by vacuolated epithelium showing lactational change. Many rounded concentric calcifications of various sizes are seen within the ductal lumina. These show characteristic appearances of Liesegang rings. In some ducts, the rings surround amorphous material with histologically identifiable calcific deposits. A mild chronic inflammatory infiltrate is seen in-between ducts. Liesegang rings are spherical, ring-like structures that show a characteristic appearance of concentric laminations...
Source: Journal of Clinical Pathology - December 13, 2016 Category: Pathology Authors: Robinson, A., Shaaban, A. M. Tags: Immunology (including allergy), Breast cancer, Inflammation, Clinical diagnostic tests Virtual case of the month Source Type: research

Basophil-derived IL-4 plays versatile roles in immunity
Abstract Recent studies demonstrated that basophils play crucial and non-redundant roles in the immune system, in spite of the fact that they are the rarest granulocytes and represent less than 1 % of peripheral blood leukocytes. In response to various stimuli, basophils release effector molecules stored in their cytoplasmic granules, including chemical mediators and proteases, and also secrete cytokines and chemokines. In this review, we will focus on the physiological and pathological roles of basophil-derived IL-4. Basophils can readily produce large quantities of IL-4 and are therefore the important source of...
Source: Seminars in Immunopathology - May 9, 2016 Category: Pathology Source Type: research

Self‐limited coeliac‐like enteropathy: a series of 18 cases highlighting another coeliac disease mimic
ConclusionsHistopathologists need to be aware that a coeliac disease‐like enteropathy may occur in the setting of an acute gastrointestinal illness and resolve without sequelae.
Source: Histopathology - July 28, 2015 Category: Pathology Authors: Ian S Brown, Andrew Bettington, Mark Bettington, Christophe Rosty Tags: Original Article Source Type: research

Self‐limited coeliac like enteropathy: a series of 18 cases highlighting another coeliac disease mimic
ConclusionsHistopathologists need to be aware that a coeliac disease like enteropathy may occur in the setting of an acute gastrointestinal illness and resolve without sequelae.This article is protected by copyright. All rights reserved.
Source: Histopathology - June 4, 2015 Category: Pathology Authors: Ian S. Brown, Andrew Bettington, Mark Bettington, Christophe Rosty Tags: Original Article Source Type: research

A critical assessment of two real-time PCR assays targeting the (SSU) rRNA and gdh genes for the molecular identification of Giardia intestinalis in a clinical laboratory
Conclusions The Verweij real-time PCR was robust and the most sensitive assay suited for use as a first-line diagnostic test for giardiasis.
Source: Journal of Clinical Pathology - August 18, 2014 Category: Pathology Authors: Boadi, S., Polley, S. D., Kilburn, S., Mills, G. A., Chiodini, P. L. Tags: Immunology (including allergy), Tropical medicine (infectious diseases), Clinical diagnostic tests Original article Source Type: research