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Infectious Disease: Adenoviruses
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Total 599 results found since Jan 2013.
DJ-1 alleviates oxidative stress injury by activating the Nrf2 pathway in rats with cerebral ischemia-reperfusion injury
Nan Fang Yi Ke Da Xue Xue Bao. 2021 May 20;41(5):679-686. doi: 10.12122/j.issn.1673-4254.2021.05.07.ABSTRACTOBJECTIVE: To investigate the antioxidant effect of DJ-1 (Park7) in rats with cerebral ischemia/reperfusion (IR) injury and its potential mechanism.OBJECTIVE: A total of 108 SD rats were randomly divided into sham-operated group, middle cerebral artery occlusion (MCAO) group, Scramble group, DJ-1 siRNA group, negative control (NC) group and DJ-1 overexpression group. Except for those in the sham group, all the rats were subjected to MCAO to establish models of cerebral IR injury. In DJ-1 siRNA and DJ-1 overexpression...
Source: Journal of Southern Medical University - June 17, 2021 Category: Universities & Medical Training Authors: L Li L Peng J Zhu J Wu Y Zhao Source Type: research
Runx2 overexpression promotes bone repair of osteonecrosis of the femoral head (ONFH)
CONCLUSIONS: Overexpression of Runx2 can improve osteoblastic phenotype maintenance of MSCs and promote necrotic bone repair of ONFH.PMID:37029290 | DOI:10.1007/s11033-023-08411-7
Source: Molecular Biology Reports - April 7, 2023 Category: Molecular Biology Authors: Hai-Jia Xu Xiang-Zhong Liu Lu Yang Yu Ning Liang-Liang Xu Da-Ming Sun Wen Liao Yi Yang Zhang-Hua Li Source Type: research
Evaluation of Adenovirus-Mediated Down-Regulation of Connective Tissue Growth Factor on Postoperative Wound Healing After Experimental Glaucoma Surgery.
CONCLUSIONS: Down-regulation of CTGF is effective in inhibiting postoperative scarring in vivo. This suggests that RNAi with CTGF siRNA may potentially pave the road for a novel therapeutic strategy to improve glaucoma surgery results.
PMID: 26554857 [PubMed - as supplied by publisher]
Source: Current Eye Research - November 10, 2015 Category: Opthalmology Authors: Lim DH, Kim TE, Kee C Tags: Curr Eye Res Source Type: research
