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Infectious Disease: Tuberculosis

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Total 482 results found since Jan 2013.

BCG vaccine ’s off-target effects on allergic, inflammatory, and autoimmune diseases: Worth another shot?
Allergy is an exaggerated immune response to foreign antigens resulting from a combination of genetic, epigenetic and environmental interactions. Immune responses misdirected against intrinsic antigens can lead to autoimmunity. The incidence of allergic and autoimmune diseases is rising, constituting a global public health challenge with broad socioeconomic implications. The Bacille Calmette-Gu érin (BCG) vaccine is a live attenuated Mycobacterium bovis vaccine given to millions of newborns worldwide to prevent tuberculosis.
Source: Journal of Allergy and Clinical Immunology - October 18, 2021 Category: Allergy & Immunology Authors: Asimenia Angelidou, Laure F. Pittet, Denise Faustman, Nigel Curtis, Ofer Levy Tags: Paradigms and perspectives Source Type: research

Indoor Urban Environment and Conventional Risk Factors for Pediatric Tuberculosis Among 1 –12 Years Old Children in a Megacity in Pakistan: A Matched Case–Control Study
Pediatric Allergy, Immunology, and Pulmonology,Volume 35, Issue 4, Page 158-165, December 2022.
Source: Pediatric, Allergy, Immunology, and Pulmonology - December 15, 2022 Category: Respiratory Medicine Authors: Ambreen Sahito Zafar Fatmi Muhammad Masood Kadir Fehmina Arif Source Type: research

Drug Patch Testing in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: A Systematic Review
CONCLUSION: Published reports suggest that PT in SJS/TEN is useful and safe. AEDs have been tested most frequently and show the highest positivity rate. There is a critical need for large-scale studies with standardized methodology to obtain reproducible data on PT in SJS/TEN.PMID:36649833 | DOI:10.1016/j.anai.2023.01.006
Source: Annals of Allergy, Asthma and Immunology - January 17, 2023 Category: Allergy & Immunology Authors: Danielle E Novack Melinda Braskett Scott D Worswick Brandon L Adler Source Type: research

Dysregulation of Immunity in Pulmonary Fibrosis is Associated with Increased Myeloid-specific Triggering Receptor-1 and Transforming Growth Factor-beta1 Expression
In this study, the expression of triggering receptor expressed on myeloid cells-1 (TREM-1) as a stimulator for the production of TGF-β1 and also CD4+CD25+Foxp3+ regulatory cells were investigted in FP patients. Sixteen UIP, 14 NSIP and 4 pulmonary fibrosis following Mycobacterium tuberculosis (TB) infection patients, were compared with 12 healthy controls. The frequency of blood CD14+TGF-β1+ and CD14+TREM1+-gated monocytes and CD4+CD25+Foxp3+ regulatory T cells (Treg), as well as the plasma levels of TGF-β1 and IL‑10 were measured. Fibrosis patients compared to healthy controls had a greater frequency of CD14+TGF-β1+...
Source: Iranian Journal of Allergy, Asthma and Immunology - April 1, 2023 Category: Allergy & Immunology Authors: Shima Rasouli Jalal Heshmatnia Nariman Mosaffa Majid Marjani Esmaeil Mortaz Source Type: research