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Infectious Disease: Coronavirus

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Total 2650 results found since Jan 2013.

The role of Pannexin-1 channels, ATP, and purinergic receptors in the pathogenesis of HIV and SARS-CoV-2
Curr Opin Pharmacol. 2023 Sep 19;73:102404. doi: 10.1016/j.coph.2023.102404. Online ahead of print.ABSTRACTInfectious agents such as human immune deficiency virus-1 (HIV) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) use host proteins to infect, replicate, and induce inflammation within the host. A critical component of these diseases is the axis between pannexin-1 channels, extracellular ATP, and purinergic receptors. Here, we describe the potential therapeutic role of Pannexin-1/purinergic approaches to prevent or reduce the devastating consequences of these pathogens.PMID:37734241 | DOI:10.1016/j.coph.2023.102404
Source: Current Opinion in Pharmacology - September 21, 2023 Category: Drugs & Pharmacology Authors: Cristian A Hernandez Eliseo A Eugenin Source Type: research

Salivary antiviral and antibacterial properties in the encounter of SARS-CoV-2
Curr Pharm Des. 2023 Sep 4. doi: 10.2174/1381612829666230904150823. Online ahead of print.ABSTRACTDue to the high mortality rate of COVID-19 and its high variability and mutability, it is essential to know the body's defense mechanisms against this virus. Saliva has numerous functions, such as digestion, protection, and antimicrobial effects. Salivary diagnostic tests for many oral and systemic diseases will be available soon because saliva is a pool of biological markers. The most important antiviral and antibacterial compounds identified in saliva include lysozyme, lactoferrin (LF), mucins, cathelicidin, salivary secreto...
Source: Current Pharmaceutical Design - September 6, 2023 Category: Drugs & Pharmacology Authors: Nooshin Mohtasham Rahimeh Bargi Alieh Farshbaf Maryam Vahabzadeh Shahri Kiana Kamyab Hesari Farnaz Mohajertehran Source Type: research

Telogen effluvium and COVID-19: a cross-sectional study
CONCLUSIONS: In our study, the incidence of TE was highly related to COVID-19 infections among both sexes. However, the incidence was greater among the female population. The awareness level toward post-COVID-19 TE was poor among most of the participants in our study.PMID:37667959 | DOI:10.26355/eurrev_202308_33437
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: A Aldahish R Vasudevan H Salem A Alqahtani S AlQasim A Alqhatani M Al Shahrani L Al Mohsen M Hajla D Calina J Sharifi-Rad Source Type: research

Study on early markers of death in patients with COVID-19
CONCLUSIONS: Underlying heart disease, lymphocyte count, glomerular filtration rate, lactate, oxygenation index, SOFA score, and MuLBSTA score were associated with the risk of death in severe and critical COVID-19 patients.PMID:37667958 | DOI:10.26355/eurrev_202308_33436
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: B-Y Yuan X-F Guo X-W Gong Y-B Yang Y-D Gao Y-D Yuan Source Type: research

Telogen effluvium and COVID-19: a cross-sectional study
CONCLUSIONS: In our study, the incidence of TE was highly related to COVID-19 infections among both sexes. However, the incidence was greater among the female population. The awareness level toward post-COVID-19 TE was poor among most of the participants in our study.PMID:37667959 | DOI:10.26355/eurrev_202308_33437
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: A Aldahish R Vasudevan H Salem A Alqahtani S AlQasim A Alqhatani M Al Shahrani L Al Mohsen M Hajla D Calina J Sharifi-Rad Source Type: research

Study on early markers of death in patients with COVID-19
CONCLUSIONS: Underlying heart disease, lymphocyte count, glomerular filtration rate, lactate, oxygenation index, SOFA score, and MuLBSTA score were associated with the risk of death in severe and critical COVID-19 patients.PMID:37667958 | DOI:10.26355/eurrev_202308_33436
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: B-Y Yuan X-F Guo X-W Gong Y-B Yang Y-D Gao Y-D Yuan Source Type: research

Effect of a Family Pharmacist System on Medication Adherence of Patients with Dyslipidemia during a COVID-19 Epidemic
In this study, using anonymously processed receipt data from 700 insurance pharmacies in our group, we evaluated medication adherence in patients taking statin drugs before, during the first and second years of coronavirus disease 2019 (COVID-19) epidemic in terms of medication persistence and medication possession, and compared the results between the family pharmacist group (FP group) and non-family pharmacist group (NoFP group). The odds ratios of good medication adherence (medication persistence and medication possession) rates for the FP group relative to the NoFP group were 1.446 [95% confidence interval (CI): 1.210-...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - September 4, 2023 Category: Drugs & Pharmacology Authors: Mamoru Maeda Yoshitaka Hasegawa Ryota Tsukioka Miya Oishi Source Type: research