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Source: Pharmaceutical Biology
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Total 28 results found since Jan 2013.
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1
CONCLUSION: Our findings indicate that EGCG promotes intestinal epithelial cell proliferation and barrier function after I/R injury in vitro and in vivo via activation of Nurr1.PMID:37621064 | PMC:PMC10461505 | DOI:10.1080/13880209.2023.2245445
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Jiacheng Gao Yuhang Wang Zirui Jia Jiaming Xue Tingting Zhou Guo Zu Source Type: research
Hydroxysafflor yellow A inhibits endothelial cell ferroptosis in diabetic atherosclerosis mice by regulating miR-429/SLC7A11
CONCLUSIONS: HSYA is expected to become an important health drug to prevent the occurrence and development of T2DM/AS.PMID:37410531 | DOI:10.1080/13880209.2023.2225543
Source: Pharmaceutical Biology - July 6, 2023 Category: Drugs & Pharmacology Authors: Jianjie Rong Chuanyong Li Qiang Zhang Guangfeng Zheng Weijian Fan Zhichang Pan Shuming Shi Source Type: research
Metformin ameliorates ferroptosis in cardiac ischemia and reperfusion by reducing NOX4 expression via promoting AMPK α
CONCLUSIONS: Met shows effectiveness in relieving ferroptosis in cardiac I/R. In the future, Met may be an effective drug for relieving ferroptosis in cardiac I/R patients clinically.PMID:37288723 | DOI:10.1080/13880209.2023.2212700
Source: Pharmaceutical Biology - June 8, 2023 Category: Drugs & Pharmacology Authors: Zhenhua Wu Yunpeng Bai Yujuan Qi Chao Chang Yan Jiao Yaobang Bai Zhigang Guo Source Type: research
Schisandrin B promotes senescence of activated hepatic stellate cell via NCOA4-mediated ferritinophagy
CONCLUSIONS: Sch B could ameliorate hepatic fibrosis through the promotion of activated HSCs senescence, which might be attributed to its induction of NCOA4-mediated ferritinophagy and subsequent iron overload.PMID:37010139 | DOI:10.1080/13880209.2023.2189908
Source: Pharmaceutical Biology - April 3, 2023 Category: Drugs & Pharmacology Authors: Mingyue Ma Na Wei Jieren Yang Tingting Ding Anping Song Lerong Chen Shuguo Zheng Huanhuan Jin Source Type: research
Baicalein attenuates bleomycin-induced lung fibroblast senescence and lung fibrosis through restoration of Sirt3 expression
CONCLUSIONS: Baicalein preserved the BLM-induced downregulation of lung Sirt3 expression, and thus the suppression of TGF-β1/Smad signalling pathway and lung fibrosis, which might provide an experimental basis for treatment of IPF.PMID:36815239 | DOI:10.1080/13880209.2022.2160767
Source: Pharmaceutical Biology - February 23, 2023 Category: Drugs & Pharmacology Authors: Yuan Ji-Hong Ma Yu Yuan Ling-Hong Gong Jing-Jing Xu Ling-Li Wang Lv Jin Yong-Mei Source Type: research
Kazinol B protects H9c2 cardiomyocytes from hypoxia/reoxygenation-induced cardiac injury by modulating the AKT/AMPK/Nrf2 signalling pathway
CONCLUSIONS: KB prevented H/R-induced cardiomyocyte injury via modulating the AKT and AMPK-mediated Nrf2 induction. KB might be a promising drug candidate for managing ischemic cardiac disorders.PMID:36740871 | DOI:10.1080/13880209.2023.2173247
Source: Pharmaceutical Biology - February 6, 2023 Category: Drugs & Pharmacology Authors: Qian Zhang Yuan-Ye Dang Xiu Luo Ji-Jun Fu Zhi-Cong Zou Xue-Jing Jia Guo-Dong Zheng Chu-Wen Li Source Type: research
