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Total 379 results found since Jan 2013.

Lessons From Localized Chronic Rhinosinusitis With Nasal Polyps
Allergy Asthma Immunol Res. 2021 Nov;13(6):827-829. doi: 10.4168/aair.2021.13.6.827.NO ABSTRACTPMID:34734501 | PMC:PMC8569025 | DOI:10.4168/aair.2021.13.6.827
Source: Allergy, Asthma and Immunology Research - November 4, 2021 Category: Allergy & Immunology Authors: Sung-Woo Cho Dong-Young Kim Source Type: research

Translating lessons learned on the role of HLA in immunological responses in LEAP to peanut OIT Trials: IMPACT and POISED
We recently identified an interaction between HLA and oral exposure in LEAP: HLA-DQA1*01:02 had a protective role with induction of epitope specific IgG4 associated with peanut consumption, while it was a risk allele for peanut allergy associated with peanut avoidance. The latter is consistent with prior population-based genetics studies. We expanded these gene-environment analyses to two peanut Oral immunotherapy (OIT) trials in peanut allergic individuals: the IMPACT and POISED studies.
Source: Journal of Allergy and Clinical Immunology - February 1, 2022 Category: Allergy & Immunology Authors: Kanika Kanchan, Gautam Shankar, Michelle Huffaker, Henry Bahnson, R Sharon Chinthrajah, Srinath Sanda, Monali Manohar, George Du Toit, Ingo Ruczinski, Gideon Lack, Kari Nadeau, Stacie Jones, Gerald Nepom, Rasika Mathias Source Type: research

Lessons from the IMPAACT of coronavirus disease 2019 public health restrictions on food allergy-associated anxiety
Generalized anxiety disorder is among the most common mental health disorder and for which an instrument, the Generalized Anxiety Disorder 7-item scale (GAD-7), has been available to assess this condition for nearly 2 decades.1 During the coronavirus disease 2019 (COVID-19) pandemic, symptoms associated with generalized anxiety disorder have broadly increased, albeit with a disproportionately higher risk among mothers, parents aged 18 to 44 years, those with household incomes less than $100,000 Canadian, or those with certain preexisting mental health conditions, including anxiety.
Source: Annals of Allergy, Asthma and Immunology - July 23, 2022 Category: Allergy & Immunology Authors: Michael A. Golding, Jennifer L.P. Protudjer Tags: Editorial Source Type: research

Creating a kinder world for children with food allergies: Lessons from the coronavirus disease 2019 pandemic
Ann Allergy Asthma Immunol. 2022 Oct;129(4):397-398. doi: 10.1016/j.anai.2022.03.037.NO ABSTRACTPMID:36155695 | DOI:10.1016/j.anai.2022.03.037
Source: Annals of Allergy, Asthma and Immunology - September 26, 2022 Category: Allergy & Immunology Authors: Lisa M Bartnikas Wanda Phipatanakul Source Type: research

Tixagevimab-Cilgavimab Rollout on Common Variable Immunodeficient Patients: Early Lessons from an Academic Allergy and Immunology Clinic
Tixagevimab-cilgavimab is a combination of two monoclonal antibodies against SARS-CoV-2. In December 2021, the FDA issued emergency use authorization for intramuscular injection of tixagevimab-cilgavimab for prophylaxis against SARS-CoV-2 in immunocompromised patients. Shortly thereafter, our clinic distributed tixagevimab-cilgavimab to patients with Common Variable Immunodeficiency (CVID). To our knowledge, no prior study has looked at effects of this monoclonal antibody combination on CVID patients.
Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Daniela Dluzynski, Taha Al-Shaikhly, Maria Paula Henao Source Type: research

The need for change: Lessons learned from Food and Drug Administration-approved peanut oral immunotherapy
Ann Allergy Asthma Immunol. 2023 May;130(5):542-543. doi: 10.1016/j.anai.2023.01.031.NO ABSTRACTPMID:37137601 | DOI:10.1016/j.anai.2023.01.031
Source: Annals of Allergy, Asthma and Immunology - May 3, 2023 Category: Allergy & Immunology Authors: S Shahzad Mustafa Douglas P Mack Source Type: research

80 years of skin testing evaluation in annals
When reading the article entitled “Evaluation of skin testing in allergy: a discussion of causative factors in misleading reactions,” one cannot help but acknowledge that Lieutenant Commander Steele's review written 80 years ago is a lesson in humility.1 Well before the discovery of immunoglobulin E or the mast cell, Dr Steele a cknowledges skin testing's utility no differently than we would today. He writes that it is only a valuable adjunct to the clinical findings while rejecting the skeptic's view that it is “a semi-cabalistic rite bordering on charlatanism” or the overzealous advocate's overinterpretation of minor variations.
Source: Annals of Allergy, Asthma and Immunology - September 1, 2023 Category: Allergy & Immunology Authors: John J. Oppenheimer, Harold Nelson Tags: Editorial Source Type: research