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Total 379 results found since Jan 2013.

Biomarkers for Severe Asthma: Lessons From Longitudinal Cohort Studies
Allergy Asthma Immunol Res. 2021 May;13(3):375-389. doi: 10.4168/aair.2021.13.3.375.ABSTRACTSevere asthma (SA) is a heterogeneous disease characterized by uncontrolled symptoms, frequent exacerbations, and lung function decline. The discovery of phenotypes and endotypes of SA significantly improves our understanding of its pathophysiology and allows the advent of biologics blocking multiple molecular targets. The advances have mainly been made in type 2-high asthma associated with elevated type 2 inflammatory biomarkers such as immunoglobulin E (IgE), interleukins (IL)-4, IL-5, and IL-13. Previous clinical trials have demo...
Source: Allergy, Asthma and Immunology Research - March 18, 2021 Category: Allergy & Immunology Authors: Youngsoo Lee Quang Luu Quoc Hae Sim Park Source Type: research

Anaphylaxis and digital medicine
Purpose of review Digital medicine (mHealth) aims to help patients and healthcare providers (HCPs) improve and facilitate the provision of patient care. It encompasses equipment/connected medical devices, mHealth services and mHealth apps (apps). An updated review on digital health in anaphylaxis is proposed. Recent findings In anaphylaxis, mHealth is used in electronic health records and registries. It will greatly benefit from the new International Classification of Diseases-11 rules and artificial intelligence. Telehealth has been revolutionised by the coronavirus disease 2019 pandemic, and lessons learnt ...
Source: Current Opinion in Allergy and Clinical Immunology - September 2, 2021 Category: Allergy & Immunology Tags: ANAPHYLAXIS AND INSECT ALLERGY: Edited by Gianenrico Senna and Mariana Castells Source Type: research

Allergen-specific T cells and clinical features of food allergy: Lessons from CoFAR immunotherapy cohorts
Berin et al show that high levels of food-specific Type 2 CD4+ cells making IL-4 or IL-13 not only decrease with food allergen immunotherapy, but high levels of these cells at baseline predict a poor response to immunotherapy.
Source: Journal of Allergy and Clinical Immunology - October 12, 2021 Category: Allergy & Immunology Authors: M. Cecilia Berin, Charuta Agashe, A. Wesley Burks, David Chiang, Wendy F. Davidson, Peter Dawson, Alexander Grishin, Alice K. Henning, Stacie M. Jones, Edwin H. Kim, Donald Y.M. Leung, Madhan Masilamani, Amy M. Scurlock, Scott H. Sicherer, Robert A. Wood, Source Type: research

Lessons From Localized Chronic Rhinosinusitis With Nasal Polyps
Allergy Asthma Immunol Res. 2021 Nov;13(6):827-829. doi: 10.4168/aair.2021.13.6.827.NO ABSTRACTPMID:34734501 | DOI:10.4168/aair.2021.13.6.827
Source: Allergy, Asthma and Immunology Research - November 4, 2021 Category: Allergy & Immunology Authors: Sung-Woo Cho Dong-Young Kim Source Type: research