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Drug: Dexamethasone

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Total 8422 results found since Jan 2013.

Should we be concerned when COVID-19-positive patients take opioids to control their pain? Insights from a pharmacological point of view
CONCLUSIONS: Clinicians should keep in mind the frequent DDIs with drugs extensively metabolized by the CYP450 system and prefer opioids undergoing a limited hepatic metabolism. Identification and management of DDIs and dissemination of the related knowledge should be a major goal in the delivery of chronic care to ensure optimized patient outcomes and facilitate updating recommendations for COVID-19 therapy in frail populations, namely comorbid, poly-medicated patients or individuals suffering from substance use disorder.PMID:34337735 | DOI:10.26355/eurrev_202107_26399
Source: European Review for Medical and Pharmacological Sciences - August 2, 2021 Category: Drugs & Pharmacology Authors: S Natoli R Carpenedo E Chin è F Vannicola F Leonardis M Dauri Source Type: research

The efficacy and safety of triplet regimens based on pomalidomide and dexamethasone for treatment of relapsed/refractory multiple myeloma: a systematic review and meta-analysis
CONCLUSIONS: Three-drug regimens based on pomalidomide and dexamethasone could yield excellent overall response rate to relapsed/refractory multiple myeloma, but there are still various adverse events; therefore, consequent studies should address these adverse events.PMID:36394758 | DOI:10.26355/eurrev_202211_30162
Source: European Review for Medical and Pharmacological Sciences - November 17, 2022 Category: Drugs & Pharmacology Authors: K-Y Liao Y Liu H Xiong X-M Chen X-W Zhang C-L Huang Source Type: research

Severe osteoporosis in a young man with bilateral Cushing ’s syndrome: a case report
ConclusionThe early identification of Cushing ’s syndrome, with measures based on the assessment of risks and benefits, remains the best way to prevent its progression and reduce the morbidity of the condition. Despite the unavailability of genetic analysis for a precise etiological definition, it is possible to take efficient measures to avo id future damage.
Source: Journal of Medical Case Reports - June 17, 2023 Category: General Medicine Source Type: research

The high incidence of steroid-induced hyperglycaemia in hospital
Conclusions: We conclude that steroid-induced hyperglycaemia is common in hospital. Patients should be monitored for hyperglycaemia upon commencement of high-dose steroid therapy and treatment commenced as indicated.
Source: Diabetes Research and Clinical Practice - January 7, 2013 Category: Endocrinology Authors: Ashley C. Fong, N Wah. Cheung Tags: Critial care and education Source Type: research

Effect of intravenous pulse dexamethasone versus daily oral prednisolone on bone mineral density in dermatology patients: Is it a site-specific response ?
Conclusion: Dermatologists need to be aware of the detrimental effects of high-dose intravenous pulsed glucocorticoids on bone mineral density and assessment of this parameter should be done before the initiation of therapy and also at regular intervals thereafter. During follow up, either the lumbar spine or the head of radius can be used to assess the osteopenic effect of intravenous pulse steroids, whereas the lumbar spine is a better site for this evaluation in patients on oral steroids.
Source: Indian Journal of Dermatology, Venereology and Leprology - February 16, 2018 Category: Dermatology Authors: Sanjeev Handa Gurjeet Singh Amanjot Kaur Arora Niranjan Khandelwal Vivek Gupta Source Type: research