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Drug: Methotrexate

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Total 6619 results found since Jan 2013.

1260 Medical Treatment Success of Recurrent Ectopic Pregnancy vs. Primary Ectopic Pregnancy: A Case Control Study
ConclusionOur study suggests that while women with REP may not represent a unique sub-group of women with EP, medical treatment success with a single-dose regimen of MTX is lower than expected and hence different regimens should be considered.
Source: Journal of Minimally Invasive Gynecology - October 15, 2019 Category: OBGYN Source Type: research

Pancytopenia After Low-Dose Methotrexate Therapy in Two Hemodialysis Patients with Rheumatoid Arthritis
We present two hemodialysis patients with RA who presented with a complication of severe pancytopenia after treatment with MTX. After receiving various supportive and blood purification treatments, both patients recovered. We reviewed twenty-four pancytopenia patients on dialysis associated with methotrexate. Among these patients, high morbidity and mortality were observed, indicating that MTX should be used cautiously in the absence of alternatives in such a population. Compared with the patients who recovered, the deceased patients showed a lower level of leukocytes. Which dialysis method might be the best choice is uncl...
Source: The American Journal of the Medical Sciences - September 25, 2021 Category: General Medicine Authors: Tao Pu Yu Ni Pan-Hong Li Dan Yu Qiong Yu Li-Mei Yu Source Type: research

Sarcoidosis - a multisystem disease
Swiss Med Wkly. 2022 Jan 14;152:w30049. doi: 10.4414/smw.2022.w30049. eCollection 2022 Jan 3.ABSTRACTSarcoidosis is a systemic inflammatory disease, characterised by granuloma formation upon an unknown trigger in genetically predisposed individuals. The inflammation is characterised by an activation of both the innate immune system, with macrophages differentiating into epitheloid cells and dendritic cells, and the adaptive immune system, particularly T helper (Th) 1 and Th17 cells. Since all organs can be affected to varying extents, clinical presentation is often diverse. Most commonly, the lungs, lymph nodes, skin and e...
Source: Swiss Medical Weekly - January 24, 2022 Category: General Medicine Authors: Daniel P Franzen Martin Brutsche Jakob Nilsson Christian B öni C écile Daccord Oliver Distler Dieter Elsener Manuela Funke-Chambour Christiane Gruner Helen Hayward-K önnecke Katrin E Hostettler Thomas K ündig Camillo Ribi J örg D Seebach Harald Seege Source Type: research

Primary Central Nervous System Lymphoma in a Patient with Down Syndrome
We report our experience with a patient with Down syndrome in whom PCNSL was diagnosed. The patient, a 48-year-old man with a diagnosis of Down syndrome, had no history of malignant tumors. The patient visited the hospital with complaints of left hemiparesis and gait disturbance. A thorough examination revealed the brain tumors, and tumor biopsy confirmed the diagnosis of PCNSL. The final pathological diagnosis was diffuse large B-cell lymphoma of the central nervous system. Chemotherapy with rituximab, methotrexate, procarbazine, and vincristine was administered, and whole-brain irradiation was planned in conjunction with...
Source: Journal of Nippon Medical School - June 1, 2022 Category: Universities & Medical Training Authors: Ami Shibata Fumio Yamaguchi Kazuma Sasaki Shoji Yokobori Akio Morita Source Type: research