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Sequential rapid oral desensitization to rifampin and moxifloxacin for the treatment of active mycobacterium tuberculosis
Publication date: Available online 9 November 2016 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Scott T. Benken, Sharmilee M. Nyenhuis, Sean Dunne
Source: The Journal of Allergy and Clinical Immunology: In Practice - November 9, 2016 Category: Allergy & Immunology Source Type: research

Rifamycin induced leukocytoclastic vasculitis. A rare side-effect of anti-tuberculous chemotherapy
We describe a case of leucocytoclastic vasculitis (LCV) caused by rifamycins.A 53 year old female presented with cough, night sweats and upper lobe nodules. Bronchial-alveolar lavage confirmed fully sensitive mycobacterium tuberculosis (TB).She commenced treatment with rifampicin, isoniazid, ethambutol and pyrizinazmide. At 4 weeks she developed an extensive purpuric rash, malaise and joint aches. There was no evidence of other infections or connective tissue disorders on extensive screening. Her inflammatory markers were elevated. A punch biopsy of her shin demonstrated leukocytoclastic vasculitis of the superficial dermi...
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Ewence, A., Dodd, J., Tewari, A., Akhras, V., Aul, R. Tags: 10.2 Tuberculosis Source Type: research

A case of rib tuberculosis and chest wall abscess with multi-drug hypersensitivity reactions.
In this report, we present an 85-year-old male patient desensitized due to the development of allergy against multi-drugs with rib tuberculosis and chest wall abscess to whom, culture, drug susceptibility and genotypical tests were applied. In November 2012, the patient applied to a medical center with complaints of swelling and pain under the right rib, underwent rib resection and eventually diagnosed as rib TB by histopathological examination. However, the anti-TB treatment was discontinued due to the hypersensitivity reactions in the skin and in addition to the hepatic and renal dysfunction side effects. The patient had...
Source: Mikrobiyoloji Bulteni - December 2, 2015 Category: Microbiology Tags: Mikrobiyol Bul Source Type: research