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Associations between Children's asthma and allergic symptoms and phthalates in dust in metropolitan Tianjin, China
This study shows that some phthalates are associated with allergic and asthma symptoms in children.PMID:35508265 | DOI:10.1016/j.chemosphere.2022.134786
Source: Chemosphere - May 4, 2022 Category: Chemistry Authors: Changqi Zhu Yuexia Sun Yuxuan Zhao Jing Hou Qingnan Zhang Pan Wang Source Type: research

Perfluoroalkyl substances are linked to incident chronic spontaneous urticaria: A nested case-control study
In conclusion, serum PFASs are associated with an increased risk of incident CSU, and PFBA and PFHpA might be the effective compounds.PMID:34583294 | DOI:10.1016/j.chemosphere.2021.132358
Source: Chemosphere - September 28, 2021 Category: Chemistry Authors: Minxue Shen Yi Xiao Yuzhou Huang Danrong Jing Juan Su Dan Luo Yanying Duan Shuiyuan Xiao Jie Li Xiang Chen Source Type: research

Molecules, Vol. 25, Pages 2129: Valorisation of By-Products from Soybean (Glycine max (L.) Merr.) Processing
Cravotto In recent years, increased awareness of the health benefits associated with consuming soy-based foods, knowledge of milk-related allergies and a move towards more sustainable food production have led to an increase in the number of available soy-based products. The biggest producers in the world, the USA, South America and China, are from the Pacific region. This enormous production is accompanied by the accumulation of related by-products, in particular, a substance that is known as okara. Okara is a paste that is rich in fibre (50%), protein (25%), fat (10%), vitamins and trace elements. Its proper use wou...
Source: Molecules - April 30, 2020 Category: Chemistry Authors: Colletti Attrovio Boffa Mantegna Cravotto Tags: Review Source Type: research

Molecules, Vol. 24, Pages 2131: Hispidulin Inhibits Mast Cell-Mediated Allergic Inflammation through Down-Regulation of Histamine Release and Inflammatory Cytokines
im Kwon Hispidulin (4′,5,7-trihydroxy-6-methoxyflavone) is a natural compound derived from traditional Chinese medicinal herbs, and it is known to have an anti-inflammatory effect. Here, we investigated the effect of hispidulin on the immunoglobulin E (IgE)-mediated allergic responses in rat basophilic leukemia (RBL)-2H3 mast cells. When RBL-2H3 cells were sensitized with anti-dinitrophenyl (anti-DNP) IgE and subsequently stimulated with DNP-human serum albumin (HSA), histamine and β-hexosaminidase were released from the cells by degranulation of activated mast cells. However, pretreatment...
Source: Molecules - June 4, 2019 Category: Chemistry Authors: Kim Min Kim Kim Kwon Tags: Article Source Type: research

Molecules, Vol. 24, Pages 102: Ethnomedicinal, Phytochemical and Pharmacological Investigations of Perilla frutescens (L.) Britt.
d Perilla frutescens (L.) Britt. (PF) is an annual herbal medicinal, aromatic, functional food, and ornamental plant that belongs to the mint family, Lamiaceae. The origin of perilla traces back to East Asian countries (China, Japan, Korea, Taiwan, Vietnam, and India), where it has been used as a valuable source of culinary and traditional medicinal uses. The leaves, seeds, and stems of P. frutescens are used for various therapeutic applications in folk medicine. In the absence of a comprehensive review regarding all aspects of perilla, this review aims to present an overview pertaining to the botanical drug, ethnobota...
Source: Molecules - December 28, 2018 Category: Chemistry Authors: Hiwa M. Ahmed Tags: Review Source Type: research

Molecules, Vol. 23, Pages 3114: Discovery of a Natural Syk Inhibitor from Chinese Medicine through a Docking-Based Virtual Screening and Biological Assay Study
This study demonstrated that tanshinone I is a Syk inhibitor with mast cell degranulation inhibitory activity. Tanshinone I may be a potential lead compound for developing effective and safe Syk-inhibiting drugs.
Source: Molecules - November 28, 2018 Category: Chemistry Authors: Xing Wang Junfang Guo Zhongqi Ning Xia Wu Tags: Article Source Type: research

Phytochemical variation among the traditional Chinese medicine Mu Dan Pi from Paeonia suffruticosa (tree peony)
In this study, the metabolome variation within Mu Dan Pi collected from 372 tree peony cultivars was systematically investigated. In total, 42 metabolites were identified, comprising of 14 monoterpene glucosides, 11 tannins, 8 paeonols, 6 flavonoids, and 3 phenols. All cultivars revealed similar metabolite profiles, however, they were further classified into seven groups on the basis of their varying metabolite contents by hierarchical cluster analysis. Traditional cultivars for Mu Dan Pi were found to have very low metabolite contents, falling into clusters I and II. Cultivars with the highest amounts of metabolites were ...
Source: Phytochemistry - December 23, 2017 Category: Chemistry Source Type: research