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Heterozygous CARD9 mutation favors the development of allergic bronchopulmonary aspergillosis
CONCLUSION: Our study provides the genetic evidence showing that the heterozygous mutation of CARD9S12N, followed by allele expression imbalance of CARD9S12N, facilitates the development of ABPA.PMID:37461235 | DOI:10.1097/CM9.0000000000002786
Source: Chinese Medical Journal - July 18, 2023 Category: General Medicine Authors: Xia Xu Haiwen Lu Jianxiong Li Jielin Duan Zhongwei Wang Jiawei Yang Shuyi Gu Rongguang Luo Shuo Liang Wei Tang Fengying Zhang Jingqing Hang Juan Ge Xin Lin Jieming Qu Xinming Jia Jinfu Xu Source Type: research

Seasonal variation of airborne fungal diversity and community structure in urban outdoor environments in Tianjin, China
Airborne fungi are ubiquitous in human living environments and may be a source of respiratory problems, allergies, and other health issues. A 12 months study was performed to investigate the diversity, concentration and community structure of culturable airborne fungi in different outdoor environments of Tianjin City, using an HAS-100B air sampler. A total of 1,015 fungal strains belonging to 175 species and 82 genera of Ascomycota 92.5%, Basidiomycota 7%, and Mucoromycota 0.3% were isolated and identified using morphological and molecular analysis. The most abundant fungal genera were Alternaria 35%, Cladosporium 18%, Pen...
Source: Frontiers in Microbiology - January 9, 2023 Category: Microbiology Source Type: research

IJERPH, Vol. 14, Pages 979: Investigation on Indoor Air Pollution and Childhood Allergies in Households in Six Chinese Cities by Subjective Survey and Field Measurements
This study focuses on the effect of indoor pollution on Chinese schoolchildren and the relationship between specific household and health problems suffered. The epidemiological questionnaire survey and the field measurement of the indoor thermal environment and primary air pollutants including CO2, fine particulate matter (PM2.5), chemical pollutants and fungi were performed in six Chinese cities. A total of 912 questionnaires were eligible for statistical analyses and sixty houses with schoolchildren aged 9–12 were selected for field investigation. Compared with Chinese national standards, inappropriate indoor relative ...
Source: International Journal of Environmental Research and Public Health - August 29, 2017 Category: Environmental Health Authors: Jinhua Hu Nianping Li Yang Lv Jing Liu Jingchao Xie Huibo Zhang Tags: Article Source Type: research