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Characterization of α-Glucosidases From Lutzomyia longipalpis Reveals Independent Hydrolysis Systems for Plant or Blood Sugars
In this report, the authors consider that transglycosylation might be an adaptation for the obtention of monosaccharides from sucrose without the increase in osmolarity, as a simple hydrolytic reaction of a 0.7 M sucrose solution (phloem concentration) might result in osmotic shock for the midgut epithelial cells. In this respect, L. longipalpis enzymes might have the same biochemical adaptation. It would be very interesting to observe if this is a common trait of α-glucosidase from insects feeding on nectar or phloem sap, and verify if this is a case of evolutionary divergence or convergence. Two main mechanisms o...
Source: Frontiers in Physiology - April 9, 2019 Category: Physiology Source Type: research

Current vector control challenges in the fight against malaria in Brazil
Abstract In Brazil, malaria is an important public health problem first reported in 1560. Historically, fluctuations in malaria cases in Brazil are attributed to waves of economic development; construction of railroads, highways, and hydroelectric dams; and population displacement and land occupation policies. Vector control measures have been widely used with an important role in reducing malaria cases. In this review article, we reviewed the vector control measures established in the Brazilian territory and aspects associated with such measures for malaria. Although some vector control measures are routinely used in Braz...
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 8, 2019 Category: Tropical Medicine Source Type: research

Molecular Detection of Leishmania DNA in Wild-Caught Phlebotomine Sand Flies (Diptera: Psychodidae) From a Cave in the State of Minas Gerais, Brazil
Leishmania spp. are distributed throughout the world, and different species are associated with varying degrees of disease severity. In Brazil, Leishmania transmission involves several species of phlebotomine sand flies that are closely associated with different parasites and reservoirs, and thereby giving rise to different transmission cycles. Infection occurs during the bloodmeals of sand flies obtained from a variety of wild and domestic animals, and sometimes from humans. The present study focused on detection of Leishmania DNA in phlebotomine sand flies from a cave in the state of Minas Gerais. Detection of Leishmania...
Source: Journal of Medical Entomology - January 11, 2017 Category: Biology Authors: Carvalho, G. M. L., Brazil, R. P., Rego, F. D., Ramos, M. C. N. F., Zenobio, A. P. L. A., Andrade Filho, J. D. Tags: Vector/Pathogen/Host Interaction, Transmission Source Type: research