• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Mineralizing angiopathy with basal ganglia stroke after minor head trauma; a clinical profile and follow up study of a large series of paediatric patients from North India
CONCLUSION: Minor head trauma leading to basal ganglia stroke in children was the most common cause of paediatric stroke in our patients. In follow-up most patients had recovered fully, though a significant minority did not recover completely.PMID:34077857 | DOI:10.1016/j.ejpn.2021.05.011
Source: European Journal of Paediatric Neurology - June 2, 2021 Category: Neurology Authors: Roshni Bahri Radhe Shyam Sharma Vivek Jain Source Type: research

Moyamoya disease: a spectrum of clinical and radiological findings in a series of eight paediatric patients
AbstractMoyamoya disease (MMD) is a progressive steno-occlusive vasculopathy at the  circle of Willis, characteristically involving the supra-clinoid segment of internal carotid arteries and their proximal branches with prominent collateral artery formation. Here we present, a series of imaging findings and varied clinical presentation of eight cases (n = 8) of MMD in the pediatric population (aged 0–18 years) after a retrospective review and detailed clinical evaluation. Detailed clinical history and examination were performed of eight pediatric patients of MMD with varied presentations. Magnetic resonance imaging...
Source: Acta Neurologica Belgica - February 4, 2021 Category: Neurology Source Type: research

A Chinese Family With Adult-Onset Leigh-Like Syndrome Caused by the Heteroplasmic m.10191T > C Mutation in the Mitochondrial MTND3 Gene
Conclusion The m.10191T>C mutation in the mtDNA of the complex I (CI) subunit of MTND3 results in the substitution of a highly conserved amino acid (p.Ser45Pro) within the ND3 protein, leading to CI dysfunction through impaired enzyme catalysis rather than impaired stability or assembly, causing a broad clinical spectrum of disorders (26). Patients with the m.10191T>C mutation are rare. In the present study, we report on a family of patients with the extremely rare adult-onset Leigh-like syndrome with the m.10191T>C mutation. Including the two patients from our reported family, the m.10191T...
Source: Frontiers in Neurology - April 17, 2019 Category: Neurology Source Type: research

Spinning Out of Control: The Black Box of Basilar and Hemiplegic Migraine (P7.176)
CONCLUSIONS:In this retrospective study, triptans were used effectively with no subsequent vascular events for the abortive treatment of migraines with basilar and hemiplegic features. This data also suggests that beta blockers, tricyclic anti-depressants, anti-convulsants, and Botox injections have some efficacy in the treatment of migraines with basilar type and hemiplegic features.Disclosure: Dr. Krel has nothing to disclose. Dr. Mathew has nothing to disclose. Dr. Spinner has received personal compensation for activities with Merz Pharma and Allergan Inc. as speaker bureau member. Dr. Joshi has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Krel, R., Mathew, P., Spinner, W., Joshi, S. Tags: Headache: Treatment Source Type: research