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Specialty: Internal Medicine
Condition: Disability
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Total 183 results found since Jan 2013.
Stroke: causes and clinical features
Stroke is a clinically defined syndrome of acute, focal neurological deficit attributed to vascular injury (infarction, haemorrhage) of the central nervous system. It is the second leading cause of death and disability worldwide. Stroke is not a single disease but is caused by a wide range of risk factors, disease processes and mechanisms. Hypertension is the most important modifiable risk factor, although its contribution differs for different subtypes. Most (85%) strokes are ischaemic, predominantly caused by small vessel arteriolosclerosis, cardioembolism and large artery athero-thromboembolism.
Source: Medicine - July 25, 2023 Category: Internal Medicine Authors: Stephen JX. Murphy, David J. Werring Tags: Acute neurology Source Type: research
Stroke: management and prevention
Acute stroke treatment requires clear protocols to rapidly triage patients – using appropriate investigations – for mechanical thrombectomy and intravenous thrombolysis. Computed tomography (CT) excludes haemorrhage, CT angiography locates the occluded vessel, and CT perfusion and perfusion magnetic resonance imaging identify viable tissue. An organized approach to str oke care in a specialist environment reduces disability and saves lives. Adoption of a ‘care bundle’ approach, including the active management of pyrexia and hyperglycaemia, and early screening for swallowing difficulties, is beneficial.
Source: Medicine - July 25, 2023 Category: Internal Medicine Authors: Gina Hadley, Ivie I. Gbinigie, Joyce S. Balami, Alastair M. Buchan Tags: Acute neurology Source Type: research
Assessment of bidirectional relationships between brain imaging-derived phenotypes and stroke: a Mendelian randomization study
Stroke is a major cause of mortality and long-term disability worldwide. Whether the associations between brain imaging-derived phenotypes (IDPs) and stroke are causal is uncertain.
Source: BMC Medicine - July 25, 2023 Category: Internal Medicine Authors: Ke Yu, Xiao-Feng Chen, Jing Guo, Sen Wang, Xiao-Ting Huang, Yan Guo, Shan-Shan Dong and Tie-Lin Yang Tags: Research article Source Type: research
Immediate Statin After Acute Stroke Reduces Disability Immediate Statin After Acute Stroke Reduces Disability
Intensive statin therapy immediately after mild ischemic stroke or high-risk TIA reduces the risk for a poor functional outcome vs delaying 72 hours, the INSPIRES trial shows.Medscape Medical News
Source: Medscape Internal Medicine Headlines - June 9, 2023 Category: Internal Medicine Tags: Neurology & Neurosurgery News Source Type: news
Inflammatory markers in patients with hypertension
Br J Hosp Med (Lond). 2023 May 2;84(5):1-8. doi: 10.12968/hmed.2022.0531. Epub 2023 May 22.ABSTRACTHypertension is a chronic disease with high levels of morbidity and disability. Elevated blood pressure can lead to many complications and is the main risk factor for stroke, heart failure and nephropathy. Factors associated with hypertension and inflammatory response differ from those associated with vascular inflammation. The immune system plays a vital role in the pathophysiology of hypertension. Inflammation is particularly relevant in the progression of cardiovascular diseases, which has led to extensive research on infl...
Source: British Journal of Hospital Medicine - May 26, 2023 Category: Internal Medicine Authors: Chen Yihui Gong Yanfeng Source Type: research
