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Nutrition and neurodevelopment: the search for candidate nutrients in the Seychelles Child Development Nutrition Study
Neurotoxicology. 2020 Dec;81:300-306. doi: 10.1016/j.neuro.2020.09.021. Epub 2020 Oct 14.ABSTRACTThis review examines the role of nutrients in child development and outlines the key nutrients identified as potentially important to neurodevelopment among high fish consumers in the Seychelles Child Development Nutrition Study (SCDNS). It describes the clinical assessment of these nutrients in the blood and breast milk samples collected from the cohort of 300 pregnant women who were recruited, at their first antenatal visit, on the SCDNS. These key nutrients include the long chain polyunsaturated fatty acids (LCPUFA), docosoh...
Source: Neurotoxicology - March 20, 2021 Category: Neurology Authors: J J Strain Maxine P Bonham Emeir M Duffy Julie M W Wallace Paula J Robson Thomas W Clarkson Conrad Shamlaye Source Type: research
Ovarian stimulation for oocyte donation: a systematic review and meta-analysis
AbstractBACKGROUNDSince its introduction in the 1980s, oocyte donation (OD) has been largely integrated into ART. Lately, both demand and the indications for OD have increased greatly. Oocyte donors are healthy and potentially fertile women undergoing voluntarily ovarian stimulation (OS). Selection of the optimal type of stimulation is of paramount importance in order to achieve the most favourable outcomes for the oocyte recipients, but most importantly for the safety of the oocyte donors.OBJECTIVE AND RATIONALEThis is the first systematic review (SR) with the objective to summarize the current evidence on OS in oocyte do...
Source: Human Reproduction Update - March 20, 2021 Category: OBGYN Source Type: research
A Biomarker for Amniotic Fluid Embolism: The Search Continues
BJOG. 2021 Jul 6. doi: 10.1111/1471-0528.16833. Online ahead of print.ABSTRACTResearch into the pregnancy associated cytokine storm-like condition historically known as amniotic fluid embolism (AFE) has been hampered by a lack of unique diagnostic criteria. In its classic form, the clinical presentation of this condition is unmistakable. In less classic presentations, each of the clinical hallmarks of AFE (depressed ventricular function, lung injury and coagulopathy) may, in isolation, be seen in other obstetric conditions. Indeed, much of the confusion arising from previously published case series purporting to describe w...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - July 6, 2021 Category: OBGYN Authors: Steven Leigh Clark Source Type: research
The search for aliens within us: a review of evidence and theory regarding the foetal microbiome
Crit Rev Microbiol. 2021 Nov 17:1-13. doi: 10.1080/1040841X.2021.1999903. Online ahead of print.ABSTRACTThe microbiome is believed to be established during the birthing process through exposure to the maternal microbiome and immediate external environment. The absence of a microbiome prior to birth is based on the sterile womb hypothesis, which was formulated at the beginning of the 20th century and is supported primarily by the culture-based approach in microbiological studies.Findings of bacterial presence in products of fertilization such as the placenta, amniotic fluid, foetal membranes, and umbilical cord blood in stu...
Source: Critical Reviews in Microbiology - November 17, 2021 Category: Microbiology Authors: Richard Cari ño Lena Takayasu Wataru Suda Hiroaki Masuoka Kazuhiro Hirayama Shoko Konishi Masahiro Umezaki Source Type: research
