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Comparison of outcomes of direct-acting oral anticoagulants vs. vitamin K antagonists in patients with bioprosthetic heart valves or valve repair: a systematic review and meta-analysis
CONCLUSIONS: Findings suggest that the use DOACs in patients with AF with bioprosthetic valve replacement or repair is comparatively better than vitamin K antagonists in reducing the risk of bleeding and thrombo-embolic events. Future studies with a randomized design and larger sample sizes are needed to further substantiate these findings.PMID:34355372 | DOI:10.26355/eurrev_202108_26457
Source: European Review for Medical and Pharmacological Sciences - August 6, 2021 Category: Drugs & Pharmacology Authors: L-L Tang S-W Liang H-L Shi J-J Ye Source Type: research

Postoperative atrial fibrillation in paraesophageal hernia repair: can it be prevented?
We report the case of an 85-year-old female with a history of untreated hypertension (HTN) and no prior history of AF, who presented 5 days after an elective repair of a paraesophageal hernia with recurrence of a large type III paraesophageal hiatal hernia, AF, and subsequent acute thromboembolic ischemic stroke. Patient ’s AF resolved shortly after treatment with calcium channel blocker. The risk of stroke is high in patients who develop AF and a period of 48 h after onset of AF is usually considered safe as the risk of stroke is low in this time period. However, this may not be the case during the perioperativ e peri...
Source: Perioperative Medicine - July 20, 2021 Category: Surgery Source Type: research

Evaluation of Prescribing Practices and Outcomes Using Direct-Acting Oral Anticoagulants After Cardiac Surgery
Clin Ther. 2021 May 30:S0149-2918(21)00203-4. doi: 10.1016/j.clinthera.2021.04.009. Online ahead of print.ABSTRACTPURPOSE: Cardiac surgery patients frequently require anticoagulation. Warfarin remains the preferred agent, and a few trials have reported negative outcomes with the use of direct-acting oral anticoagulants (DOACs) in these patients. Therefore, limited literature exists that supports the dosing, safety, and efficacy of DOACs within the cardiac surgery population.METHODS: This single-center, retrospective analysis was conducted at a tertiary academic medical center. All data were extrapolated from electronic med...
Source: Clinical Therapeutics - June 3, 2021 Category: Drugs & Pharmacology Authors: Dareen M Kanaan Bryan M Cook Julie Kelly Rhynn Malloy Source Type: research

Initial Clinical Experience with Mitral Valve Translocation for Secondary Mitral Regurgitation.
CONCLUSIONS: Mitral valve translocation creates a large surface of coaptation and effectively corrects FMR. Further study is needed to demonstrate the long-term durability and clinical utility of this operation. PMID: 33440174 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - January 10, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Gammie JS, Quinn RW, Strauss ER, Wang L, D'Ambra MN, Hung J, Bernstein DA, Tran D, Rice MK, Holmes SD, Pasrija C Tags: Ann Thorac Surg Source Type: research

Early and mid-term outcomes of minimally invasive mitral valve repair via right mini-thoracotomy: 5-year experience with 129 consecutive patients
ConclusionsEarly and mid-term results of MIMVr were satisfactory, with low rates of perioperative morbidity and recurrent MR, as well as reoperation and death. Furthermore, the protocols for patient selection and surgical approach were considered to be appropriate.
Source: General Thoracic and Cardiovascular Surgery - January 5, 2021 Category: Cardiovascular & Thoracic Surgery Source Type: research

Left atrial appendage perforation with Watchman device implantation: Strategies for surgical repair
We describe a case of left atrial appendage perforation during Watchman device implantation requiring emergency repair of the left atrium using sternotomy and cardiopulmonary bypass. Technical consideration s for surgical decision making are discussed; in hemodynamically unstable patients as well as those at high risk for embolization.
Source: Journal of Cardiac Surgery - December 1, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Saqib Masroor, Qiong Qiu, Mohamad Alghothani, Rajesh Gupta, George V. Moukarbel Tags: CASE REPORT Source Type: research

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