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Atrial Cardiopathy: Redefining Stroke Risk Beyond Atrial Fibrillation
Atrial fibrillation (AF) and ischemic stroke are dual epidemics in society, both associated with poor clinical outcomes, patient disability, and significant healthcare expenditure. The conditions are interrelated and share complex causal pathways. Risk stratification algorithms such as the CHADS2 and CHA2DS2-VASc score offer predictive value in stroke and systemic embolism risk in the AF population, however, have limitations. Recent evidence suggests that an intrinsically prothrombotic atrial substrate may precede and promote AF and lead to thromboembolic events independent of the arrhythmia, allowing for a window of inter...
Source: The American Journal of Cardiology - June 28, 2023 Category: Cardiology Authors: Jessica Chu Zhang, Aditya Bhat Source Type: research

Atrial fibrillation: Profile and burden of an evolving epidemic in the 21st century
Abstract: Background: Atrial fibrillation (AF) represents an increasing public health challenge with profound social and economic implications.Methods: A comprehensive synthesis and review of the AF literature was performed. Overall, key findings from 182 studies were used to describe the indicative scope and impact of AF from an individual to population perspective.Results: There are many pathways to AF including advancing age, cardiovascular disease and increased levels of obesity/metabolic disorders. The reported population prevalence of AF ranges from 2.3%–3.4% and historical trends reflect increased AF incidence. Es...
Source: International Journal of Cardiology - February 4, 2013 Category: Cardiology Authors: Jocasta Ball, Melinda J. Carrington, John J.V. McMurray, Simon Stewart Tags: Reviews Source Type: research

Update on atrial fibrillation
Atrial fibrillation (AF) is the most common arrhythmia and accounts for one-third of hospitalizations for rhythm disorders in the United States [1]. Atrial fibrillation is of public health importance and profoundly increases morbidity, mortality, and health-related expenditures. Morbidities include outcomes such as heart failure, stroke and the deleterious effects on quality of life (QOL), functional status, and cognition. In the United States and Western Europe, the aging population and the accompanying rise in the prevalence of AF have magnified its toll on morbidity and healthcare costs.
Source: Trends in Cardiovascular Medicine - June 21, 2016 Category: Cardiology Authors: Amanulla Khaji, Peter R. Kowey Source Type: research

Evolving concepts in atrial fibrillation epidemiology: Advancing knowledge about cardiovascular health in sub-Saharan Africa
Atrial fibrillation (AF) is the most common cardiac arrhythmia presenting in the daily clinical practice [1]. In the last 50  years, AF prevalence and incidence have been shown to constantly increase, progressively becoming a worldwide healthcare issue, with relevant public health expenditure, both in terms of clinical management and consequences related to the main clinical adverse events related to AF (i.e. stroke, ma jor bleeding, cardiovascular events) [1,2].
Source: International Journal of Cardiology - July 4, 2018 Category: Cardiology Authors: Marco Proietti Tags: Editorial Source Type: research

Comparison of Frequency of Atrial Fibrillation in Blacks versus Whites and the Utilization of Race in a Novel Risk Score
Atrial fibrillation (AF) is the most prevalent sustained arrhythmia in the world, with over 30 million people affected as of 2010.1 The number of patients projected to develop AF will double over the next decade.2 AF is independently associated with an increased risk of stroke,3 heart failure (HF),4 and mortality.5 It is not surprising, thus, that AF assumes a sizeable share of health care expenditure and its magnitude is reaching epidemic proportions.6 Blacks despite having a higher prevalence of traditional risk factors for AF, such as HF, hypertension, and diabetes mellitus, have been shown to have a lower incidence of AF.
Source: The American Journal of Cardiology - August 27, 2020 Category: Cardiology Authors: Gurukripa N. Kowlgi, Sampath Gunda, Santosh K. Padala, Jayanthi N. Koneru, Abhishek J. Deshmukh, Kenneth A. Ellenbogen Source Type: research

Po-02-165 cost implications of adherence to guideline-recommended anticoagulation among patients with atrial fibrillation at high risk of stroke
Caring for patients with AF is expensive. Estimated costs account for up to 3% of total annual heath care expenditure in many developed nations. Due to an aging population, the clinical and economic burden is expected to increase over the next decade. There are limited contemporary economic data to facilitate the development of cost-efficient strategies for improving the quality of AF care.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Brennan Ballantyne, Amity Quinn, Flora Au, Stephen B. Wilton, Derek Chew Source Type: research