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Condition: Alcoholism
Drug: Docetaxel

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Total 16 results found since Jan 2013.

Aldehyde dehydrogenase 2 rs671 genetic polymorphisms are associated with chemotherapy-induced nausea and vomiting
CONCLUSION: ALDH2 gene mutation at rs671 is a risk factor contributing to the occurrence of CINV, and understanding of the underlying mechanism may help to more effectively control the occurrence of CINV.PMID:37439175 | PMC:PMC10339303 | DOI:10.12122/j.issn.1673-4254.2023.06.18
Source: Journal of Southern Medical University - July 13, 2023 Category: Universities & Medical Training Authors: Q Yang X Liu Y Jiang J Ma Source Type: research

Fight Aging! Newsletter, May 2nd 2022
In this study, we tested the therapeutic potential of VHHASC and a newly generated VHH against murine ASC (VHHmASC) to target ASC specks in vitro and in vivo. We show that pre-incubation of extracellular ASC specks with VHHASC abrogated their inflammatory functions in vitro. Recombinant VHHASC rapidly disassembled pre-formed ASC specks and thus inhibited their ability to seed the nucleation of soluble ASC. Notably, VHHASC required prior cytosolic access to prevent inflammasome activation within cells, but it was effective against extracellular ASC specks released following caspase-1-dependent loss of membrane integrity, an...
Source: Fight Aging! - May 1, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Morning Chronotype Decreases the Risk of Chemotherapy-Induced Peripheral Neuropathy in Women With Breast Cancer
CONCLUSION: Our results suggest that the morning chronotype is a protective factor against the development of CIPN in patients with breast cancer who were treated with docetaxel.TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01887925.PMID:35132840 | DOI:10.3346/jkms.2022.37.e34
Source: J Korean Med Sci - February 8, 2022 Category: General Medicine Authors: Kyung-Lak Son Dooyoung Jung Kwang-Min Lee Chan-Woo Yeom Gyu Han Oh Tae-Yong Kim Seock-Ah Im Kyung-Hun Lee David Spiegel Bong-Jin Hahm Source Type: research