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Gynecologic Surgery in the Obese Patient
Obesity is a chronic multifactorial disease that presents serious health risks due to excessive fat accumulation in adipose tissue . Determinants such as genetics, psychosocial factors, the environment, poor diet, and physical inactivity all have a role in its development. Obesity was defined in 1998 by the National Institutes of Health clinical guidelines as body mass index (BMI) ≥30 . Obese individuals are at higher risk for many comorbid conditions and for overall mortality than are non-obese individuals. Some of these conditions include type 2 diabetes mellitus, hypertension, coronary artery disease, stroke, obstruc...
Source: The Journal of Minimally Invasive Gynecology - January 23, 2014 Category: OBGYN Authors: Karen Cooper, Tommaso Falcone Tags: Editorial Source Type: research

Drospirenone-containing oral contraceptive pills and the risk of venous and arterial thrombosis: a systematic review.
CONCLUSIONS: Our systematic review suggests that drospirenone-containing OCP use is associated with a higher risk for VTE than both no OCP use and levonorgestrel-containing OCP use. PMID: 23530659 [PubMed - in process]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - May 25, 2013 Category: OBGYN Authors: Wu C, Grandi S, Filion K, Abenhaim H, Joseph L, Eisenberg M Tags: BJOG Source Type: research

Drospirenone‐containing oral contraceptive pills and the risk of venous and arterial thrombosis: a systematic review
BackgroundPrevious studies have provided conflicting results regarding the effect of drospirenone‐containing oral contraceptive pills (OCPs) on the risk of venous and arterial thrombosis. ObjectivesTo conduct a systematic review to assess the risk of venous thromboembolism (VTE), myocardial infarction (MI), and stroke in individuals taking drospirenone‐containing OCPs. Search strategyWe systematically searched CINAHL, the Cochrane Library, Dissertation & Abstracts, EMBASE, HealthStar, Medline, and the Science Citation Index from inception to November 2012. Selection criteriaWe included all case reports, observation...
Source: BJOG: An International Journal of Obstetrics and Gynaecology - March 26, 2013 Category: OBGYN Authors: CQ Wu, SM Grandi, KB Filion, HA Abenhaim, L Joseph, MJ Eisenberg Tags: Systematic Review Source Type: research

Reply
We appreciate the interest that Drs Aznar and Cerdá have expressed in our Clinical Opinion piece. We did not intend to minimize the importance of factor V Leiden as a risk factor for venous thromboembolism (VTE) in women taking combined oral contraceptives (COCs). However, we primarily addressed the risks of myocardial infarction (MI) and ischemic stroke (IS), which are arterial thrombotic events, with COCs. Accordingly, we cited some well-established risk factors for MI and IS, and we suggested that tools such as the Framingham risk calculator may be helpful adjuncts to American College of Obstetricians and Gynecologists...
Source: American Journal of Obstetrics and Gynecology - March 1, 2013 Category: OBGYN Authors: Christopher R. McCartney, Jennifer P. Beller Tags: Letters to the Editors Source Type: research

Lessons Learned From the Women's Health Initiative Trials of Menopausal Hormone Therapy.
Abstract We re-evaluate the Women's Health Initiative findings and their implications for clinical practice. Menopausal hormone therapy (HT) was effective for relief of vasomotor symptoms, and the risk of coronary heart disease (CHD) tended to be reduced in women close to menopause compared with the increased risk in women more distant from menopause. In recently menopausal women, short-term absolute risks of stroke and venous thromboembolism were small. Estrogen plus progestin therapy, but not estrogen therapy, increased the risk of breast cancer with a suggestion of greater risk when initiated close to the menop...
Source: Obstetrics and Gynecology - January 1, 2013 Category: OBGYN Authors: Rossouw JE, Manson JE, Kaunitz AM, Anderson GL Tags: Obstet Gynecol Source Type: research

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