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Specialty: Cardiology
Condition: Thrombosis

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Total 3531 results found since Jan 2013.

Characteristics and Prognosis of Stroke in Living Donor Renal Transplant Recipients
CONCLUSIONS: The underlying etiologies of stroke differed in RT and HD patients. The one-year risk of MACE for stroke patients who had received an RT was lower than that for patients undergoing HD and comparable with that of patients with no RRT.PMID:34776472 | DOI:10.5551/jat.63189
Source: Journal of Atherosclerosis and Thrombosis - November 15, 2021 Category: Cardiology Authors: Takafumi Mizuno Takao Hoshino Kentaro Ishizuka Sono Toi Ayako Nishimura Shuntaro Takahashi Sho Wako Kazuo Kitagawa Source Type: research

Hypertriglyceridemia: A Neglected Risk Factor for Ischemic Stroke?
J Stroke. 2022 Jan;24(1):21-40. doi: 10.5853/jos.2021.02831. Epub 2022 Jan 31.ABSTRACTHypertriglyceridemia is caused by defects in triglyceride metabolism and generally manifests as abnormally high plasma triglyceride levels. Although the role of hypertriglyceridemia may not draw as much attention as that of plasma cholesterol in stroke, plasma triglycerides, especially nonfasting triglycerides, are thought to be correlated with the risk of ischemic stroke. Hypertriglyceridemia may increase the risk of ischemic stroke by promoting atherosclerosis and thrombosis and increasing blood viscosity. Moreover, hypertriglyceridemia...
Source: Atherosclerosis - February 8, 2022 Category: Cardiology Authors: Hai-Jie Liang Qing-Yi Zhang Yi-Tong Hu Guo-Qing Liu Rong Qi Source Type: research

Age and composition of the thrombus retrieved by mechanical thrombectomy from patients with acute ischemic stroke are associated with revascularization and clinical outcomes
CONCLUSION: Thrombus composition correlated with revascularization and clinical outcomes. The composition of an acute ischemic thrombus may reflect the pathophysiology of stroke and influence treatment efficacy.PMID:36126564 | DOI:10.1016/j.thromres.2022.09.004
Source: Atherosclerosis - September 20, 2022 Category: Cardiology Authors: Hisao Shimizu Kinta Hatakeyama Kozue Saito Ryogo Shobatake Nobuyuki Takahashi Jun Deguchi Hidemori Tokunaga Keiji Shimada Ichiro Nakagawa Kaoru Myochin Kazuya Sakai Masayuki Kubo Atsushi Yamashita Chiho Obayashi Kazuma Sugie Masanori Matsumoto Source Type: research

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke
DISCUSSION: The ABO locus, genetically predicted blood group A, and higher genetic propensity for venous thrombosis are more strongly associated with EOS than with LOS, supporting a stronger role of prothrombotic factors in EOS.PMID:36240095 | DOI:10.1212/WNL.0000000000201006
Source: Atherosclerosis - October 14, 2022 Category: Cardiology Authors: Thomas Jaworek Huichun Xu Brady J Gaynor John W Cole Kristiina Rannikmae Tara M Stanne Liisa Tomppo Vida Abedi Philippe Amouyel Nicole D Armstrong John Attia Steven Bell Oscar R Benavente Giorgio B Boncoraglio Adam Butterworth Cervical Artery Dissections Source Type: research

Insulin resistance in ischemic stroke: Mechanisms and therapeutic approaches
Front Endocrinol (Lausanne). 2022 Dec 15;13:1092431. doi: 10.3389/fendo.2022.1092431. eCollection 2022.ABSTRACTThe pathological condition of insulin resistance prevents the neuroprotective effects of insulin. Numerous studies have demonstrated that insulin resistance, as an independent risk factor for ischemic stroke, accelerates the formation of thrombosis and promotes the development of atherosclerosis, both of which are major mechanisms of ischemic stroke. Additionally, insulin resistance negatively affects the prognosis of patients with ischemic stroke regardless of whether the patient has diabetes, but the mechanisms ...
Source: Atherosclerosis - January 2, 2023 Category: Cardiology Authors: Peng-Fei Ding Hua-Sheng Zhang Jie Wang Yong-Yue Gao Jian-Nan Mao Chun-Hua Hang Wei Li Source Type: research

Stroke and Noninfective Native Valvular Disease
AbstractPurpose of ReviewEmbolic stroke of undetermined source is a challenging clinical entity. While less common than atrial fibrillation and endocarditis, many noninfective heart valve lesions have been associated with stroke and may be considered as culprits for cerebral infarcts when other more common causes are excluded. This review discusses the epidemiology, pathophysiology, and management of noninfective valvular diseases that are commonly associated with stroke.Recent FindingsCalcific debris from degenerating aortic and mitral valves may embolize to the cerebral vasculature causing small- or large-vessel ischemia...
Source: Current Cardiology Reports - March 27, 2023 Category: Cardiology Source Type: research

Stroke in Atrial Fibrillation and Other Atrial Dysrhythmias
AbstractPurpose of ReviewAtrial fibrillation (AF) is a major risk factor for systemic embolism and ischaemic stroke. Furthermore, AF-related strokes are associated with higher mortality, greater disability, longer hospital stays and lower rates of hospital discharge than strokes caused by other reasons. The aim of this review to summarise the existing evidence on the association of AF with ischemic stroke and provide insights on the pathophysiological mechanisms and the clinical management of patients with AF in order to reduce the burden of ischemic stroke.Recent FindingsBeyond Virchow ’s triad, several pathophysiologic...
Source: Current Cardiology Reports - March 28, 2023 Category: Cardiology Source Type: research

Machine Learning and the Conundrum of Stroke Risk Prediction
Stroke is a leading cause of death and permanent disability worldwide.1 Ischaemic stroke is the most common stroke variety, comprising more than 80% of strokes in the US.2 One mechanism of ischaemic stroke is atherosclerosis in the extracranial and intracranial arteries, with plaque rupture leading to thrombosis. The second major category is embolic stroke, in which thrombi form in the heart or the arterial/venous ...
Source: Radcliffe Cardiology - April 12, 2023 Category: Cardiology Authors: c242508f1d9059bc0f2aa9bdd5421ba2 Source Type: research

Urinary Immunoglobulin G Is a Novel Biomarker for Atherosclerotic Burden in Mild Acute Ischemic Stroke Patients
CONCLUSION: In MAIS, urinary IgG was associated with both the presence of atherosclerosis and an unfavorable outcome at 90 days after stroke onset.PMID:37704430 | DOI:10.5551/jat.64230
Source: Journal of Atherosclerosis and Thrombosis - September 13, 2023 Category: Cardiology Authors: Teppei Komatsu Motohiro Okumura Hiroyuki Kida Masakazu Ozawa Masahiro Mimori Tatsushi Kokubu Junichiro Takahashi Sumire Kurihara Takahiro Maku Haruhiko Motegi Maki Takahashi Tomotaka Shiraishi Ryoji Nakada Shiho Akiyama Tomomichi Kitagawa Takeo Sato Hirok Source Type: research