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Ischemic Stroke Outcomes in Oman: Experience of a University Hospital Based Stroke Registry (P6.278)
Conclusions:Ischemic stroke in Oman reflects the high morbidity/mortality seen in most communities in the region. Characteristics of incident stroke such as stroke recurrence, type, severity and cardiovascular comorbidity are likely the major determinants of stroke outcome. A relatively lower prevalence of extracranial artery disease and possible greater prevalence of multiple stroke mechanisms may also influence on outcomes and merit further study.Disclosure: Dr. Gujjar has nothing to disclose. Dr. Ramachandiran has nothing to disclose. Dr. Al-Asmi has nothing to disclose. Dr. Ganguly has nothing to disclose. Dr. Shoaib h...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Gujjar, A., Ramachandiran, N., Al-Asmi, A., Ganguly, S., Shoaib, R., Al-Asmi, A. Tags: Cerebrovascular Disease Health Services Research Source Type: research

In light of recently published clinical trials and their implication for clinical practice, does a large catchment area acute hospital require 24  hour CT neck and head angiography and/or neuro-interventional services in the setting of acute ischaemic stroke?
ConclusionUHL should provide routine CT angiography to all patients presenting with acute ischaemic stroke in line with current guidelines. The need for provision of neuro-interventional services on-site proved more difficult to assess and requires further analysis.
Source: Irish Journal of Medical Science - August 15, 2017 Category: General Medicine Source Type: research

Sonothrombolysis for acute ischemic stroke - Break on through to the other side
Conclusions: Sonothrombolysis appears to be a safe way to augment the effect of tPA without increasing the door to needle time with the added advantage of observing flow through the occluded artery in real time.
Source: Neurology India - January 11, 2017 Category: Neurology Authors: Sanjith Aaron Sunithi Mani AT Prabhakar P Suresh Babu Sanjeev Kumar Rohith Ninan Benjamin Ajith Sivadasan Karthik Muthusamy Anil Kumar B Patil Vivek Mathew Mathew Alexander Source Type: research

ASPECT Score and Its Application to Vasospasm in Aneurysmal Subarachnoid Haemorrhage: a Case –Control Study
AbstractDelayed cerebral ischaemia (DCI) is a significant complication of aneurysmal subarachnoid haemorrhage (aSAH) and is strongly associated with poorer outcome. The Alberta Stroke Program Early Computer Tomography (ASPECT) score is an established scoring tool, used in acute ischaemic stroke, to quantify early ischaemic changes on CT head scans. We aim to identify if ASPECT scoring correlates with functional outcome in DCI following aSAH. Retrospective case –control study. Inclusion criteria: admission to the Department of Neurosurgery at Leeds Teaching Hospitals NHS Trust (a tertiary neurosurgical centre in the Unite...
Source: Translational Stroke Research - August 9, 2022 Category: Neurology Source Type: research

Influence of gender on the risk of death and adverse events in patients with acute myocardial infarction undergoing pharmacoinvasive strategy
Abstract Pharmacoinvasive treatment is an acceptable alternative for patients with ST-segment elevation myocardial infarction (STEMI) in developing countries. The present study evaluated the influence of gender on the risks of death and major adverse cardiovascular events (MACE) in this population. Seven municipal emergency rooms and the Emergency Mobile Healthcare Service in São Paulo treated STEMI patients with tenecteplase. The patients were subsequently transferred to a tertiary teaching hospital for early (<24 h) coronary angiography. A total of 469 patients were evaluated [329 men (70.1 %)]. Compared ...
Source: Journal of Thrombosis and Thrombolysis - October 2, 2014 Category: Hematology Source Type: research

Prevalence and Risk Factors of Stress Cardiomyopathy After Convulsive Status Epilepticus in ICU Patients
Objective: Although stress cardiomyopathy has been described in association with epilepsy, its frequency in patients with convulsive status epilepticus remains unknown. Accordingly, we sought to determine the prevalence and risk factors of stress cardiomyopathy in patients admitted to the ICU for convulsive status epilepticus. Design: Prospective, descriptive, single-center study. Setting: Medical-surgical ICU of a teaching hospital. Patients: Thirty-two consecutive ventilated patients (21 men; age, 50 ± 18 yr; Simplified Acute Physiology Score II, 53 ± 15; Sequential Organ Failure Assessment, 6 ± 2) hospitalized in the...
Source: Critical Care Medicine - September 18, 2015 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Proprietary Software Enhancement of Digital Subtraction Angiography for Perfusion Mapping of Posterior Circulation (P6.022)
Conclusion: AngioViz DSA enhancement technique may reliably identify patients with intra-procedural neurovascular perfusion deficits for posterior circulation when none exists. Further larger retrospective analysis and prospective validation studies for reproducibility and reliability of this software application are needed.Disclosure: Dr. Avignon has nothing to disclose. Dr. Mehta has nothing to disclose. Dr. Korya has nothing to disclose. Dr. Arango has nothing to disclose. Dr. Brar has nothing to disclose. Dr. Moussavi has nothing to disclose. Dr. Kirmani has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Avignon, G., Mehta, S., Korya, D., Arango, A., Brar, J., Moussavi, M., Kirmani, J. Tags: Ischemic Stroke Diagnosis Source Type: research

Current treatment of central retinal artery occlusion: a national survey
ConclusionsThis survey shows that there is significant variability in treatment practices for acute CRAO in the US. Because of the high cerebrovascular and cardiovascular risk reported in this population of patients, it is notable that the approach to risk factor screening is also highly variable and many programs do not routinely refer patients to an emergency department for urgent evaluation. Finally, there appears to be equipoise among treatment teams regarding the efficacy of systemic fibrinolysis, as 53% of programs report a willingness to treat at least some patients with this modality.
Source: Journal of Neurology - December 13, 2017 Category: Neurology Source Type: research