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Specialty: Cardiology
Condition: Patent Foramen Ovale

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Total 614 results found since Jan 2013.

Patent Foramen Ovale Closure Versus Medical Therapy for Cryptogenic Stroke: An Updated Systematic Review and Meta-Analysis
ConclusionPFO closure is associated with a significant reduction in the risk of stroke compared to medical management. However, it causes an increased risk of atrial fibrillation.
Source: Indian Heart Journal - October 22, 2019 Category: Cardiology Source Type: research

Role of PFO Closure in Ischemic Stroke Prevention
AbstractPurpose of reviewTo highlight recent advancements in the management of acute ischemic stroke patients with patent foramen ovale (PFO).Recent findingsOne significant recent development was publication of long-term follow-up data from the RESPECT trial demonstrating evidence in favor of PFO closure over medical management. This data subsequently led to FDA approval for AMPLATZER ™ septal occluder in the treatment of patients aged 18 to 60 years with both PFO and no other determined etiology for ischemic stroke, otherwise referred to as embolic stroke of undetermined source. Several subsequent closure trial results...
Source: Current Treatment Options in Cardiovascular Medicine - November 13, 2019 Category: Cardiology Source Type: research

Examining the evidence for PFO closure and novel oral anticoagulants for treatment of cryptogenic stroke.
Authors: Khan R Abstract Introduction: There has been considerable study assessing the treatment of cryptogenic stroke (CS) recently. This review examines the role of patent foramen ovale (PFO) closure in CS, while also discussing the evidence for alternative medical therapies in disease treatment.Areas Covered: PFO closure for treatment of CS has been assessed in 6 randomized controlled trials (RCTs). This review summarizes the background, results and limitations of these trials. Methodological and treatment-related differences in RCTs provide potential explanations for the discordance in outcomes observed between...
Source: Expert Review of Cardiovascular Therapy - February 23, 2020 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Importance of Persistent Right-to-Left Shunt After Patent Foramen Ovale Closure in Cryptogenic Stroke Patients
Tex Heart Inst J. 2020 Aug 1;47(4):244-249. doi: 10.14503/THIJ-17-6582.ABSTRACTPercutaneous closure of patent foramen ovale (PFO) is widely performed to prevent recurrent stroke or transient ischemic attack in patients with cryptogenic stroke. However, the influence of different degrees of right-to-left shunting (RLS) has rarely been reported. We retrospectively evaluated the cases of 268 patients with cryptogenic stroke who underwent PFO closure at our hospital from April 2012 through April 2015. In accordance with RLS severity, we divided the patients into 2 groups: persistent RLS during normal breathing and the Valsalva...
Source: Texas Heart Institute Journal - January 20, 2021 Category: Cardiology Authors: Lu He Gesheng Cheng Yajuan Du Yushun Zhang Source Type: research