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Libera nos a malo
Percutaneous transluminal angioplasty for treatment of chronic cerebrospinal venous insufficiency in patients with MS: a solution or a harmful illusion? Percutaneous transluminal angioplasty (PTA) of stenosed jugular and/or azygos veins,1 also known as the ‘liberation treatment’,2 has been proposed as a solution to improve the clinical outcome of MS patients with chronic cerebrospinal venous insufficiency (CCSVI).3 In their paper van Zuuren and colleagues present the summary of a Cochrane systematic review outlining the randomised controlled trials (RCTs) on this topic and conclude that there is currently no ev...
Source: Journal of Neurology, Neurosurgery and Psychiatry - March 5, 2014 Category: Neurosurgery Authors: Baracchini, C. Tags: Immunology (including allergy), Multiple sclerosis, Stroke, Radiology, Radiology (diagnostics) Editorial commentaries Source Type: research

Is the 'liberation procedure' for multiple sclerosis really liberating?
Multiple sclerosis (MS) is an inflammatory disease, which is immune-mediated, and responds to immune-modulating therapies. However, it is uncertain what antigen, or antigens, trigger the immune system to attack the central nervous system's (CNS's) myelin. Could it be iron? The predominantly venotopic location of MS lesions in the CNS has recently been postulated to be a consequence of congenital stenosis of the internal jugular or azygous veins, causing venous congestion and hypertension, and local transmural extravasation of erythrocytes into the white matter. The erythrocytes subsequently degrade, but the residual iron r...
Source: Journal of Neurology, Neurosurgery and Psychiatry - March 5, 2014 Category: Neurosurgery Authors: Hankey, G. J., Sandercock, P., Cantisani, T. A., Celani, M. G. Tags: Immunology (including allergy), Multiple sclerosis, Stroke, Hypertension Editorial commentaries Source Type: research

Percutaneous transluminal angioplasty for treatment of chronic cerebrospinal venous insufficiency in people with multiple sclerosis: a summary of a Cochrane systematic review
Conclusions There is currently no high level evidence to support or refute the efficacy or safety of percutaneous transluminal angioplasty for treatment of CCSVI in people with MS. Clinical practice should be guided by evidence supported by well-designed randomised controlled trials: closure of some of the gaps in the evidence may be feasible at completion of the six ongoing clinical trials.
Source: Journal of Neurology, Neurosurgery and Psychiatry - March 5, 2014 Category: Neurosurgery Authors: van Zuuren, E. J., Fedorowicz, Z., Pucci, E., Jagannath, V., Robak, E. W. Tags: Immunology (including allergy), Multiple sclerosis, Stroke Source Type: research

“Liberation treatment” for chronic cerebrospinal venous insufficiency in multiple sclerosis: the truth will set you free
ConclusionCCSVI appears to be a poorly reproducible and clinically irrelevant sonographic construct. “Liberation treatment” has no proven efficacy, may exacerbate underlying disease activity and has been complicated with SAEs. “Liberation treatment” should stop being offered to MS patients even in the settings of RCTs. CCSVI appears to be a poorly reproducible and clinically irrelevant sonographic construct. “Liberation treatment” has no proven efficacy, may exacerbate underlying disease activity and has been complicated with SAEs. “Liberation treatment” should stop being offered to MS patients even in the settings of RCTs.
Source: Brain and Behavior - September 1, 2014 Category: Neurology Authors: Georgios Tsivgoulis, Simon Faissner, Konstantinos Voumvourakis, Aristeidis H. Katsanos, Nikos Triantafyllou, Nikolaos Grigoriadis, Ralf Gold, Christos Krogias Tags: Review Source Type: research

12 Innovations That Will Change Health Care and Medicine in the 2020s
Pocket-size ultrasound devices that cost 50 times less than the machines in hospitals (and connect to your phone). Virtual reality that speeds healing in rehab. Artificial intelligence that’s better than medical experts at spotting lung tumors. These are just some of the innovations now transforming medicine at a remarkable pace. No one can predict the future, but it can at least be glimpsed in the dozen inventions and concepts below. Like the people behind them, they stand at the vanguard of health care. Neither exhaustive nor exclusive, the list is, rather, representative of the recasting of public health and medic...
Source: TIME: Health - October 25, 2019 Category: Consumer Health News Authors: TIME Staff Tags: Uncategorized HealthSummit19 technology Source Type: news