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Characteristics of cerebral ischemic stroke based on moyamoya disease and atherosclerosis-associated intracranial arterial stenosis
ConclusionsDiffering from LAS stroke, MMD stroke mainly presents with WSI and does not feature with platelet hyper-aggregation and fragmentation of ulcer plaque. Whereby, focusing on perfusion improvement rather than antiplatelets and statins may be the predominant step in MMD-stroke correction.
Source: Neurological Sciences - June 9, 2021 Category: Neurology Source Type: research

Mediators of the Age Effect among Patients Treated with Carotid Artery Stenting: The Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) (P02.017)
CONCLUSIONS: These data suggest that a longer carotid artery lesion length is a significant contributor to the increased risk of CAS in the elderly. However, attenuation of the age effect was modest, less than a 10% change in the hazard ratios. Other potential mediators such as tortuosity and atherosclerosis of the aortic arch and great vessels were not assessed. Non-anatomic factors that are more common with advancing age such as cerebral white matter disease and subclinical dementia were also not assessed and may play a role in how elderly patients respond to ischemic insults.Disclosure: Dr. Voeks has nothing to disclose...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Voeks, J., Farb, R., Heck, D., Roubin, G., Moore, W., Logan, W., Longbottom, M., Howard, G., Brott, T. Tags: P02 Cerebrovascular Disease II Source Type: research

Chronic disease and lifestyle factors associated with change in sleep duration among older adults in the Singapore Chinese Health Study
This study aimed to identify factors associated with change in sleep duration in a large sample of older adults (≥ 60 years) residing in Singapore (n = 10 335). These adults were monitored as part of the Singapore Chinese Health Study, which collected information regarding daily sleep duration at baseline (assessed in 1993–1998) and at a follow‐up wave conducted over a mean of 12.7 years later (assessed in 2006–2010). Among adults sleeping 6–8 h at baseline (n = 8265), most participants (55.6%) remained 6–8 h sleepers at follow‐up, while 8.4% became short (< 6 h) and 36.0% became long (> 8�...
Source: Journal of Sleep Research - September 28, 2015 Category: Neurology Authors: Stephen F. Smagula, Woon‐Puay Koh, Renwei Wang, Jian‐Min Yuan Tags: Regular Research Paper Source Type: research