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Spinal Cord Infarction as the Initial Presentation of Systemic Lupus Erythematosus (P2.077)
CONCLUSIONS:Aggressive therapy with high dose corticosteroids and intravenous cyclophosphamide followed by oral therapy may be a successful therapeutic approach to spinal cord infarcts secondary to systemic lupus erythematosus. Study Supported by: N/ADisclosure: Dr. Michael has nothing to disclose. Dr. Hayat has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Michael, A., Hayat, G. Tags: Neurological Consequences of Autoimmune Disease Source Type: research

Teaching NeuroImages: Longitudinally extensive transverse myelitis in MELAS
A 16-year-old girl presented with acute-onset flaccid quadriparesis with urinary incontinence. Medical history unveiled generalized epilepsy since age 7 years and status epilepticus 3 years before. Multisystem compromise was absent. Family history was unremarkable. Two days after admission, generalized refractory status epilepticus occurred. Neuroimaging studies disclosed laminar cortical necrosis and longitudinally extensive transverse myelitis (LETM) in cervical and thoracic spinal cord levels (figure). Muscle biopsy disclosed subsarcolemmal mitochondrial proliferation and ragged-red fibers (figure). Genetic testing conf...
Source: Neurology - January 25, 2016 Category: Neurology Authors: Souza, P. V. S. d., Pinto, W. B. V. d. R., Oliveira, A. S. B. Tags: MRI, Metabolic disease (inherited), Spinal cord tumor, All Epilepsy/Seizures, Mitochondrial disorders RESIDENT AND FELLOW SECTION Source Type: research

Incontinence and gait disturbance after intraventricular extension of intracerebral hemorrhage
Conclusion: ICH subjects with IVH extension are at an increased risk for developing incontinence and dysmobility after controlling for factors associated with severity and disability. This finding suggests a potential target to prevent or treat long-term disability after ICH with IVH.
Source: Neurology - March 7, 2016 Category: Neurology Authors: Woo, D., Kruger, A. J., Sekar, P., Haverbusch, M., Osborne, J., Moomaw, C. J., Martini, S., Hosseini, S. M., Ferioli, S., Worrall, B. B., Elkind, M. S. V., Sung, G., James, M. L., Testai, F. D., Langefeld, C. D., Broderick, J. P., Koch, S., Flaherty, M. L Tags: Intracerebral hemorrhage ARTICLE Source Type: research

Nursing Home Residents with Seizure Disorders/Epilepsy: Prevalence, Characteristics, and Treatment Patterns (P1.080)
Conclusions: NHRs with seizure disorder/epilepsy have substantial physical and cognitive impairment. Nearly half were prescribed combination AED therapy, and >20[percnt] took 蠅3 different AEDs, suggesting refractory epilepsy. Additional research is needed to assess treatment outcomes and further define optimal care in this population.Disclosure: Dr. Zarowitz has nothing to disclose. Dr. Allen has nothing to disclose. Dr. OShea has nothing to disclose. Dr. Wang has nothing to disclose. Dr. Semenchuk has nothing to disclose. Dr. Barghout has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zarowitz, B., Allen, C., OShea, T., Wang, Z., Semenchuk, M., Barghout, V. Tags: Epilepsy/Clinical Neurophysiology: Geriatric Epilepsy, Epidemiology, and Health Services Source Type: research

Glioproliferative Lesion of the Spinal Cord Derived from Intrathecal Administration of Stem Cells (P4.234)
CONCLUSIONS: Unregulated intrathecal SCT can cause devastating complications. This patient’s highly proliferative neoplasm developing from pluripotent stem cells supports the ideological shift to employ more differentiated cells in future SCT research.Disclosure: Dr. Saad has nothing to disclose. Dr. Miller has nothing to disclose. Dr. Cagney has nothing to disclose. Dr. Chavakula has nothing to disclose. Dr. Guleria has nothing to disclose. Dr. Aizer has nothing to disclose. Dr. Ligon has nothing to disclose. Dr. Chi has nothing to disclose. Dr. Berkowitz has received royalty payments from Clinical Pathophysiology M...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Saad, M., Miller, M., Cagney, D., Chavakula, V., Guleria, I., Aizer, A., Ligon, K., Chi, J., Berkowitz, A. Tags: Neuro-oncology: Neurologic Complications of Cancer Source Type: research

Noninvasive spinal neuromodulation to map and augment lower urinary tract function in rhesus macaques.
Abstract Dysfunction of the lower urinary tract (LUT) is prevalent in neurological disorders, including multiple sclerosis, stroke, spinal cord injury and neurodegenerative conditions. Common symptoms include urgency, incontinence, and urinary retention. Recent advances in neuromodulation have resulted in improved treatments for overactive bladder symptoms of urgency, frequency, and nocturia. However, there are presently no treatments available for the induction of voiding to overcome urinary retention. We demonstrate that transcutaneous spinal cord stimulation (TSCS), a non-invasive intervention, applied over the...
Source: Experimental Neurology - August 6, 2019 Category: Neurology Authors: Havton LA, Christe KL, Edgerton VR, Gad PN Tags: Exp Neurol Source Type: research

Impairments and comorbidities in adults with cerebral palsy and spina bifida: a meta-analysis
ConclusionsMore research is needed to study health issues in adults with MD. Adults with CP or SB deal with a variety of health issues. More attention for the mental health of these adults is needed. There also is a need for accessible and adequate screening, preventive measures and clinical follow-up.
Source: Frontiers in Neurology - July 18, 2023 Category: Neurology Source Type: research

Pay attention: you can fall! The Mini-BESTest scale and the turning duration of the TUG test provide valid balance measures in neurological patients: a prospective study with falls as the balance criterion
ConclusionThe TUG turning duration and the Mini-BESTest predict the chance of being a faller. Their criterion validity as balance measures in neurological patients is substantial.
Source: Frontiers in Neurology - September 8, 2023 Category: Neurology Source Type: research

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