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Specialty: Respiratory Medicine
Condition: Hypertension

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Total 342 results found since Jan 2013.

Response to treatment assessment in patients with PAH by MRI based computational modelling
Conclusion: The non-invasive proposed metrics have the potential to assess the response to PAH therapy, reducing the RHC interventions at follow-up.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Lungu, A., Hose, R., Capener, D., Kiely, D., Wild, J., Swift, A. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

Change in right atrial minimal volume is a prognostic marker in pulmonary arterial hypertension (PAH)
Conclusion Change in minimal right atrial volume predicts mortality and maybe of value in the serial evaluation of patients on PAH therapy.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Tubman, E., Sproson, T., Capener, D., Condliffe, R., Elliot, C., Charalampopolous, A., Kiely, D., Wild, J., Swift, A. Tags: 1.3 Imaging Source Type: research

Age is independently associated with pulmonary arterial compliance in health and in patients with pulmonary vascular disease
Discussion: Advancing age is independently associated with pulmonary arterial compliance in health and disease. In contrast to younger patients, pulmonary arterial compliance does not increase in response to PAH therapy in older patients.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Swift, A., Lungu, A., Capener, D., Hammerton, C., Rothman, A., Lawrie, A., Elliot, C., Condliffe, R., Kiely, D., Wild, J. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

Pulmonary arteriovenous malformations- Evidence of under recognition in respiratory medicine?
Conclusions: Publication patterns suggest continued under recognition of pulmonary PAVMs in mainstream respiratory medicine, favouring specific inclusion of this relatively common pulmonary vascular condition within Respiratory Medicine curricula.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Shovlin, C., Gossage, J. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

Risk of cardiovascular comorbidities in patients with idiopathic pulmonary fibrosis: Analysis of Medicare data
Conclusions: Newly diagnosed IPF pts are typically sicker than non-IPF pts and have significantly higher rates of CV conditions. The higher rate of CV conditions needs to be taken into consideration for the management and treatment of pts with IPF.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Broder, M., Change, E., Papoyan, E., Popescu, I., Reddy, S., Raimundo, K., Chou, W., Stauffer, J. Tags: 6.1 Epidemiology Source Type: research

Contrasting cardiovascular responses to exercise in mitochondrial myopathy and pulmonary arterial hypertension
Conclusion: A greater response of heart rate to oxygen consumption (HR/VO2≥120 beats/L) and the presence of an abnormal plateau of O2pulse during exercise are more frequently found in patients with PAH than MM.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Degani-Costa, L. H., Rodrigues, M. T., Ramos, R. P., Ferreira, E. V. M., Fonseca, A. X. C., Gimenes, A., Bravo, D., Ota-Arakaki, J. S., Neder, J. A., Nery, L. E. Tags: 4.1 Clinical Physiology, Exercise and Functional Imaging Source Type: research

Clinical Impact of Gensini score in chronic obstructive pulmonary disease (COPD)
Conclusion: Our data suggest that high Gensini score in COPD was independently associated with cardiac co-morbidities such as triple vessel CAD and myocardial infarction.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Park, J. H., Lee, K. S., Chung, W. Y., Sheen, S., Lee, J. Y., Lim, H.-S., Shin, J.-H., Tahk, S.-J. Tags: 5.2 Monitoring Airway Disease Source Type: research

Prevalence of obstructive sleep apnea syndrome (OSAS) in men varies markedly according to definition criteria
Conclusion: Inclusion of co-morbidities in the ICSD-3 criteria does not notably increase OSAS prevalence over that determined by OSA symptoms alone. Better identification of who is at long-term risk from OSA-related complications is needed to define significant OSA.1 Heinzer R, et al. Lancet Resp Med. 2016; 4: e5-e6.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Adams, R., Appleton, S., Vakulin, A., McEvoy, D., Antic, N., Catcheside, P., Taylor, A., Wittert, G. Tags: 4.2 Sleep and Control of Breathing Source Type: research

17{beta}-Estradiol mediates superior adaptation of right ventricular function to acute strenuous exercise in female rats with severe pulmonary hypertension
17β-Estradiol (E2) exerts protective effects on right ventricular (RV) function in pulmonary arterial hypertension (PAH). Since acute exercise-induced increases in afterload may lead to RV dysfunction in PAH, we sought to determine whether E2 allows for superior RV adaptation after an acute exercise challenge. We studied echocardiographic, hemodynamic, structural, and biochemical markers of RV function in male and female rats with sugen/hypoxia (SuHx)-induced pulmonary hypertension, as well as in ovariectomized (OVX) SuHx females, with or without concomitant E2 repletion (75 μg·kg–1·day–1)...
Source: AJP: Lung Cellular and Molecular Physiology - July 31, 2016 Category: Respiratory Medicine Authors: Lahm, T., Frump, A. L., Albrecht, M. E., Fisher, A. J., Cook, T. G., Jones, T. J., Yakubov, B., Whitson, J., Fuchs, R. K., Liu, A., Chesler, N. C., Brown, M. B. Tags: CALL FOR PAPERS Source Type: research

Prognostic value of right ventricular ejection/filling parameters in IPAH using cardiac magnetic resonance: A prospective pilot study
Conclusion CMR‐derived RV TPER and TPER/TCC can reflect RV early systolic function, and may be promising predictors for long‐term prognosis in IPAH patients.
Source: Respirology - July 22, 2016 Category: Respiratory Medicine Authors: Wen Li, Tao Yang, Yan Zhang, Qing Gu, Zhi ‐Hong Liu, Xin‐Hai Ni, Qin Luo, Chang‐Ming Xiong, Jian‐Guo He Tags: Original Article Source Type: research

Comparisons of sleep apnoea rate and outcomes among patients with resistant and non‐resistant hypertension
ConclusionWe observed a modest increase in likelihood for SA among RH compared to non‐RH patients. Risks for IHE and CHF were higher for SA in RH compared to SA in non‐RH patients; however, there were no differences in risk for stroke and mortality.
Source: Respirology - July 17, 2016 Category: Respiratory Medicine Authors: Simran K. Bhandari, Jiaxiao Shi, Miklos Z. Molnar, Scott A. Rasgon, Stephen F. Derose, Csaba P. Kovesdy, David A. Calhoun, Kamyar Kalantar‐zadeh, Steven J. Jacobsen, John J. Sim Tags: Original Article Source Type: research

Comparisons of sleep apnoea rate and outcomes among patients with resistant and non ‐resistant hypertension
ConclusionWe observed a modest increase in likelihood for SA among RH compared to non‐RH patients. Risks for IHE and CHF were higher for SA in RH compared to SA in non‐RH patients; however, there were no differences in risk for stroke and mortality.
Source: Respirology - July 17, 2016 Category: Respiratory Medicine Authors: Simran K. Bhandari, Jiaxiao Shi, Miklos Z. Molnar, Scott A. Rasgon, Stephen F. Derose, Csaba P. Kovesdy, David A. Calhoun, Kamyar Kalantar ‐zadeh, Steven J. Jacobsen, John J. Sim Tags: Original Article Source Type: research

Obstructive sleep apnea is independently associated with subclinical coronary atherosclerosis among middle-aged women
Conclusion Moderate to severe OSA is independently associated with the presence of CAC in middle-aged women. These results reinforce the concept that women are also susceptible to the cardiovascular consequences of OSA.
Source: Sleep and Breathing - July 5, 2016 Category: Respiratory Medicine Source Type: research

Perioperative screening for obstructive sleep apnoea and treatment outcomes: where are the data?
Obstructive sleep apnoea (OSA) is common illness found worldwide, with a reported prevalence ranging from 9% to 24% among the general population [1]. In the USA, approximately 92% of women and 82% of men with moderate-to-severe OSA remain undiagnosed [2]. OSA carries several short- and long-term health consequences. These may range from perioperative complications to the risk of having uncontrolled hypertension, stroke, coronary artery disease and dysrhythmias, to name a few [3–8].
Source: European Respiratory Journal - June 29, 2016 Category: Respiratory Medicine Authors: Surani, S. R., Varon, J. Tags: Sleep medicine Editorials Source Type: research

The effect of sex and age on the comorbidity burden of OSA: an observational analysis from a large nationwide US health claims database
Obstructive sleep apnoea (OSA) is a highly prevalent condition but studies exploring the burden of OSA-associated comorbidities have been limited by small sample sizes with underrepresentation of women. We queried the Truven Health MarketScan Research Databases 2003–2012, which is a collection of health insurance claims for working adults and retirees with employer-sponsored health insurance. Adults with a diagnostic code for OSA with at least 12 months of follow-up from the index date of OSA diagnosis were compared to a matched random sample. Comorbidities were assessed using International Classification of Dis...
Source: European Respiratory Journal - March 31, 2016 Category: Respiratory Medicine Authors: Mokhlesi, B., Ham, S. A., Gozal, D. Tags: Sleep medicine Original Articles: Sleep Source Type: research