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Total 232 results found since Jan 2013.

Identification of embolic stroke in patients with large vessel occlusion: The Chinese embolic stroke score, CHESS
CONCLUSION: CHESS could reliably and independently identify embolic stroke as the cause of large vessel occlusion.PMID:34559949 | DOI:10.1111/cns.13729
Source: CNS Neuroscience and Therapeutics - September 24, 2021 Category: Neuroscience Authors: Lan Hong Longting Lin Gang Li Jianhong Yang Yu Geng Min Lou Mark Parsons Xin Cheng Qiang Dong Source Type: research

Human urinary kallidinogenase in acute ischemic stroke: A single-arm, multicenter, phase IV study (RESK study)
CONCLUSION: HUK had an acceptable safety and tolerability profile in AIS patients. Besides, HUK demonstrated the neurological and functional improvements in AIS, further confirming its clinical efficacy in a real-world large population.PMID:34510762 | DOI:10.1111/cns.13724
Source: CNS Neuroscience and Therapeutics - September 12, 2021 Category: Neuroscience Authors: Jun Ni Ming Yao Li-Hua Wang Ming Yu Run-Hui Li Li-Hong Zhao Jia-Chun Wang Yin-Zhou Wang Xin Wang Hai-Qing Song Ben-Yan Luo Jia-Wei Wang Yi-Ning Huang Li-Ying Cui RESK Investigators Source Type: research

Incidental findings of typical iNPH imaging signs in asymptomatic subjects with subclinical cognitive decline
ConclusionsApparent asymptomatic subjects with “iNPH” imaging characteristics presented with subclinical cognitive decline and showed worse executive function, memory, and TMT-B results than “normal” subjects. WMH seem to play a role in the etiology before ventriculomegaly. Clinical screening of individuals with incidental iNPH-character istic imaging and conspicuous results sof these neurocognitive tests needs further validation.
Source: Fluids and Barriers of the CNS - August 14, 2021 Category: Neuroscience Source Type: research

Iron chelation suppresses secondary bleeding after intracerebral hemorrhage in angiotensin II-infused mice
CONCLUSION: Iron overload plays a key role in secondary bleeding after ICH in Ang II-induced hypertensive mice. Iron chelation during the process of Ang II-induced hypertension suppresses secondary bleeding after ICH.PMID:34346561 | DOI:10.1111/cns.13706
Source: CNS Neuroscience and Therapeutics - August 4, 2021 Category: Neuroscience Authors: Jie Wang Xiao-Qin Tang Min Xia Cheng-Cheng Li Chao Guo Hong-Fei Ge Yi Yin Bo Wang Wei-Xiang Chen Hua Feng Source Type: research

Inflammation-Related circRNA Polymorphism and Ischemic Stroke Prognosis
AbstractCircRNAs belong to a novel class of noncoding RNAs that are generated by exons of genes by alternative mRNA splicing and involved in pathophysiological processes of ischemic stroke by regulating neuro-inflammation. A total of 982 patients were enrolled in our study for stroke recovery analysis. The aim of our study was to first explore the association between the inflammation-related circRNA polymorphism and functional outcome 3  months after ischemic stroke by using multivariate logistic regression model. Next, we further investigated the role of circRNA polymorphism in predicting stroke recurrence by using Cox p...
Source: Journal of Molecular Neuroscience - July 17, 2021 Category: Neuroscience Source Type: research