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Specialty: Drugs & Pharmacology
Condition: Hypertension
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Total 409 results found since Jan 2013.
Contemporary Drug Treatment of Hypertension: Focus on Recent Guidelines
AbstractThe 2017 American College of Cardiology/American Heart Association hypertension guidelines diagnose hypertension if systolic blood pressure (SBP) is ≥ 130 mmHg or diastolic blood pressure (DBP) is ≥ 80 mmHg. Increased BP is SBP 120–129 mmHg with DBP < 80 mmHg. Lifestyle measures should be used to treat individuals with increased BP. Lifestyle measures plus BP-lowering drugs should be used for secondary prevention of recurrent cardiovascular events in individuals with clinical cardiovascular disease (coronary heart disease, congestive heart fa ilure, or stroke) and an average SBP ≥ 1...
Source: Drugs - March 13, 2018 Category: Drugs & Pharmacology Source Type: research
Role of heme oxygenases in cardiovascular syndromes and co-morbidities.
CONCLUSIONS: Each of the six major categories of CVD exhibit features of pathogenesis that hold potential as future therapeutic targets, for modulated heme oxygenase activity.
PMID: 30051777 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - July 26, 2018 Category: Drugs & Pharmacology Authors: Haines DD, Tosaki A Tags: Curr Pharm Des Source Type: research
Pharmacological characterization of MT-1207, a novel multitarget antihypertensive agent
Acta Pharmacol Sin. 2021 Mar 29. doi: 10.1038/s41401-021-00636-1. Online ahead of print.ABSTRACTHypertension is a serious public health problem worldwide. MT-1207, chemically named 3-(4-(4-(1H-benzotriazole-1-yl)butyl)piperazine-1-yl) benzisothiazole hydrochloride, is a new chemical entity that has entered into clinical trial as antihypertensive agent in China. In this paper we report the pharmacological profile of MT-1207 regarding its acute, subacute, and long-term effects on hypertensive animal models, and its actions on isolated organs in vitro as well as its molecular targets. Blood pressure (BP) was measured in consc...
Source: Acta Pharmacologica Sinica - March 30, 2021 Category: Drugs & Pharmacology Authors: Tian-Ying Xu Peng Wang Jia-Sheng Tian Sheng-Li Qing Shu-Na Wang Ya-Hui Huang Jin-Yi Xu Ding-Feng Su Jian-Guo Liu Chao-Yu Miao Source Type: research
Subclinical hyperthyroidism: the cardiovascular point of view
CONCLUSIONS: Current findings mainly described possible associations with rhythm alterations, heart failure, and stroke but the effective beneficial effects of the treatment of subclinical hyperthyroidism are still lacking.PMID:33928612 | DOI:10.26355/eurrev_202104_25735
Source: European Review for Medical and Pharmacological Sciences - April 30, 2021 Category: Drugs & Pharmacology Authors: G Vidili A Delitala R Manetti Source Type: research
