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Source: Stroke
Condition: Hypertension
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Total 234 results found since Jan 2013.
Effects of Blood Pressure in the Early Phase of Ischemic Stroke and Stroke Subtype on Poststroke Cognitive Impairment Clinical Sciences
This study was to investigate the impact of BP levels in the early phase of ischemic stroke and stroke subtype on PSCI.Methods—Seven hundred and ninety-six patients with acute ischemic stroke were included. Cognitive function was assessed after stroke onset using the Montreal Cognitive Assessment. Patients were divided into quintiles according to systolic BP and diastolic BP levels in the early phase. Subtype analyses were according to Trial of ORG 10172 in Acute Stroke Treatment classification (infarct cause) and Oxfordshire Community Stroke Project classification (infarct location).Results—After adjusting for multipl...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Mingli He, Jin’e Wang, Na Liu, Xiao Xiao, Shan Geng, Pin Meng, Niu Ji, Yong’an Sun, Bingchao Xu, Yingda Xu, Xinyu Zhou, Guanghui Zhang, Xiaobing He, Zenglin Cai, Zaipo Li, Bei Wang, Bei Xu, Rutai Hui, Yibo Wang Tags: High Blood Pressure, Cognitive Impairment, Ischemic Stroke Original Contributions Source Type: research
Blood Pressure in Acute Stroke Topical Review
Source: Stroke - June 25, 2018 Category: Neurology Authors: Philip M. Bath, Jason P. Appleton, Kailash Krishnan, Nikola Sprigg Tags: High Blood Pressure, Intracranial Hemorrhage, Ischemic Stroke Topical Reviews Source Type: research
Clinical Utility of Electronic Alberta Stroke Program Early Computed Tomography Score Software in the ENCHANTED Trial Database Clinical Sciences
Background and Purpose—Clinical utility of electronic Alberta Stroke Program Early CT Score (e-ASPECTS), an automated system for quantifying signs of infarction, was evaluated in a large database of thrombolyzed patients with acute ischemic stroke.Methods—All baseline noncontrast computed tomographic scans of patients with anterior circulation acute ischemic stroke who participated in the alteplase dose arm of the randomized controlled trial ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study) were reviewed; poor quality and large (>6 mm) slice thickness were excluded. Included scans had e-ASPECTS...
Source: Stroke - May 25, 2018 Category: Neurology Authors: Simon Nagel, Xia Wang, Cheryl Carcel, Thompson Robinson, Richard I. Lindley, John Chalmers, Craig S. Anderson Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Distribution of Lacunar Infarcts in Asians With Intracerebral Hemorrhage Brief Report
Conclusions—Our findings expand on recent work showing that lobar lacunes are more frequent in CAA-ICH than hypertensive ICH. Their independent association with lobar cerebral microbleeds and brain amyloid deposition suggests a relationship with CAA even in an Asian cohort with overall higher hypertensive load.
Source: Stroke - May 25, 2018 Category: Neurology Authors: Hsin-Hsi Tsai, Marco Pasi, Li-Kai Tsai, Ya-Fang Chen, Bo-Ching Lee, Sung-Chun Tang, Panagiotis Fotiadis, Chen-Yu Huang, Ruoh-Fang Yen, M. Edip Gurol, Jiann-Shing Jeng Tags: Intracranial Hemorrhage Brief Reports Source Type: research
Effect of Antihypertensive Medication on Cerebral Small Vessel Disease Brief Report
Conclusions—AHM has a protective effect on the progression of white matter hyperintensities, but no effect on brain atrophy. There are no trials on the effect of AHM on lacunes, microbleeds, enlarged perivascular spaces, or acute small subcortical infarcts.
Source: Stroke - May 25, 2018 Category: Neurology Authors: Tessa van Middelaar, Tanja E. Argillander, Floris H.B.M. Schreuder, Jaap Deinum, Edo Richard, Catharina J.M. Klijn Tags: Primary Prevention, Hypertension, Magnetic Resonance Imaging (MRI), Meta Analysis, Cerebrovascular Disease/Stroke Brief Reports Source Type: research
Infections and Risk of Peripartum Stroke During Delivery Admissions Clinical Sciences
Conclusions—Infections present on admission increased stroke risk during delivery admissions in women with and without hypertensive disorders of pregnancy. The results were driven by genitourinary infections and sepsis. Infections may be an underrecognized precipitant of peripartum stroke.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Eliza C. Miller, Marisa Gallo, Erin R. Kulick, Alexander M. Friedman, Mitchell S.V. Elkind, Amelia K. Boehme Tags: Pregnancy, Risk Factors, Women, Cerebrovascular Disease/Stroke Original Contributions Source Type: research
Impact of Smoking on Clinical Outcome and Recanalization After Intravenous Thrombolysis for Stroke Clinical Sciences
Conclusions—Our study suggests that good outcome in smokers is mainly related to differences in baseline characteristics and not to biological effects of smoking. The higher recanalization rates in smokers, however, call for further studies.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Rebekka Kurmann, Stefan T. Engelter, Patrik Michel, Andreas R. Luft, Susanne Wegener, Meret Branscheidt, Elissavet Eskioglou, Gaia Sirimarco, Philippe A. Lyrer, Henrik Gensicke, Thomas Horvath, Urs Fischer, Marcel Arnold, Hakan Sarikaya Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Smoking and Risk of Ischemic Stroke in Young Men Brief Report
We examined the dose–response relationship between the quantity of cigarettes smoked and the odds of developing an ischemic stroke in men under age 50 years.Methods—The Stroke Prevention in Young Men Study is a population-based case–control study of risk factors for ischemic stroke in men ages 15 to 49 years. The χ2 test was used to test categorical comparisons. Logistic regression models were used to calculate the odds ratio for ischemic stroke occurrence comparing current and former smokers to never smokers. In the first model, we adjusted solely for age. In the second model, we adjusted for potential confounding ...
Source: Stroke - April 23, 2018 Category: Neurology Authors: Janina Markidan, John W. Cole, Carolyn A. Cronin, Jose G. Merino, Michael S. Phipps, Marcella A. Wozniak, Steven J. Kittner Tags: Epidemiology, Primary Prevention, Risk Factors, Secondary Prevention, Ischemic Stroke Brief Reports Source Type: research
Arterial Stiffness Is Associated With Basal Ganglia Enlarged Perivascular Spaces and Cerebral Small Vessel Disease Load Brief Report
Conclusions—We found that, in a cohort of hypertensive individuals, the arterial stiffness is associated with the total load of the cSVD, especially with lacunes and basal ganglia EPVS.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Iolanda Riba–Llena, Joan Jimenez–Balado, Xavier Castane, Anna Girona, Antonio Lopez–Rueda, Xavier Mundet, Carmen I. Jarca, Jose Alvarez–Sabin, Joan Montaner, Pilar Delgado Tags: Hypertension Brief Reports Source Type: research
Residential Proximity to Major Roadways and Risk of Incident Ischemic Stroke in NOMAS (The Northern Manhattan Study) Clinical Sciences
Conclusions—In this urban multiethnic cohort, we found evidence supporting that within-city variation in residential proximity to major roadway is associated with higher risk of ischemic stroke. An individual’s smoking history modified this association, with the association remaining only among participants not currently smokers.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Erin R. Kulick, Gregory A. Wellenius, Amelia K. Boehme, Ralph L. Sacco, Mitchell S. Elkind Tags: Aging, Cardiovascular Disease, Risk Factors, Ischemic Stroke Original Contributions Source Type: research
Risk Factors for and Clinical Consequences of Multiple Intracranial Aneurysms Clinical Sciences
Conclusions—Female sex, higher age, arterial hypertension, smoking, and familial IA are major risk factors for MIA. In addition, MIA patients are at risk for enhanced IA formation. Further studies are needed to evaluate rupture risk and the role of ethnicity, especially in the context of increased MIA identification with improved neurovascular imaging.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Ramazan Jabbarli, Thiemo Florin Dinger, Marvin Darkwah Oppong, Daniela Pierscianek, Philipp Dammann, Karsten H. Wrede, Klaus Kaier, Martin Kohrmann, Michael Forsting, Christoph Kleinschnitz, Ulrich Sure Tags: Risk Factors, Cerebral Aneurysm, Cerebrovascular Disease/Stroke, Aneurysm Original Contributions Source Type: research
Desirable Low-Density Lipoprotein Cholesterol Levels for Preventing Stroke Recurrence Clinical Sciences
Conclusions—The composite risk of stroke and transient ischemic attack reduced in the postrandomized LDL cholesterol level of 80 to 100 mg/dL after adjusting for statin usage.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00221104.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Naohisa Hosomi, Kazuo Kitagawa, Yoji Nagai, Yoko Nakagawa, Shiro Aoki, Tomohisa Nezu, Tatsuo Kagimura, Hirofumi Maruyama, Hideki Origasa, Kazuo Minematsu, Shinichiro Uchiyama, Masayasu Matsumoto Tags: Lipids and Cholesterol, Secondary Prevention, Treatment Original Contributions Source Type: research
Increased Risk of Pregnancy Complications After Stroke Clinical Sciences
Background and Purpose—The study goal was to investigate the prevalence of pregnancy complications and pregnancy loss in women before, during, and after young ischemic stroke/transient ischemic attack.Methods—In the FUTURE study (Follow-Up of Transient Ischemic Attack and Stroke Patients and Unelucidated Risk Factor Evaluation), a prospective young stroke study, we assessed the occurrence of pregnancy, miscarriages, and pregnancy complications in 223 women aged 18 to 50 years with a first-ever ischemic stroke/transient ischemic attack. Pregnancy complications (gestational hypertension, diabetes mellitus, preeclampsia, ...
Source: Stroke - March 26, 2018 Category: Neurology Authors: Mayte E. van Alebeek, Myrthe de Vrijer, Renate M. Arntz, Noortje A.M.M. Maaijwee, Nathalie E. Synhaeve, Hennie Schoonderwaldt, Maureen J. van der Vlugt, Ewoud J. van Dijk, Roel de Heus, Loes C.A. Rutten-Jacobs, Frank-Erik de Leeuw Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Plasma A{beta} (Amyloid-{beta}) Levels and Severity and Progression of Small Vessel Disease Clinical Sciences
Background and Purpose—Cerebral small vessel disease (SVD) is a frequent pathology in aging and contributor to the development of dementia. Plasma Aβ (amyloid β) levels may be useful as early biomarker, but the role of plasma Aβ in SVD remains to be elucidated. We investigated the association of plasma Aβ levels with severity and progression of SVD markers.Methods—We studied 487 participants from the RUN DMC study (Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Imaging Cohort) of whom 258 participants underwent 3 MRI assessments during 9 years. We determined baseline plasma Aβ38, Aβ40, and AÎ...
Source: Stroke - March 26, 2018 Category: Neurology Authors: Esther M.C. van Leijsen, H. Bea Kuiperij, Iris Kersten, Mayra I. Bergkamp, Ingeborg W.M. van Uden, Hugo Vanderstichele, Erik Stoops, Jurgen A.H.R. Claassen, Ewoud J. van Dijk, Frank-Erik de Leeuw, Marcel M. Verbeek Tags: Biomarkers, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research
Age-Specific Associations of Renal Impairment With Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease in Transient Ischemic Attack and Stroke Clinical Sciences
Background and Purpose—It has been hypothesized that cerebral small vessel disease (SVD) and chronic renal impairment may be part of a multisystem small-vessel disorder, but their association may simply be as a result of shared risk factors (eg, hypertension) rather than to a systemic susceptibility to premature SVD. However, most previous studies were hospital based, most had inadequate adjustment for hypertension, many were confined to patients with lacunar stroke, and none stratified by age.Methods—In a population-based study of transient ischemic attack and ischemic stroke (OXVASC [Oxford Vascular Study]), we evalu...
Source: Stroke - March 26, 2018 Category: Neurology Authors: Bian Liu, Kui Kai Lau, Linxin Li, Caroline Lovelock, Ming Liu, Wilhelm Kuker, Peter M. Rothwell Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research
